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CEL-SCI Corporation Releases Letter to Shareholders
Date:2/17/2010

s they enter Phase III.  A major drug for a large unmet medical need, unencumbered by a partnership in the biggest markets!

We feel that we have created a great situation and opportunity for our shareholders with the development of Multikine as a first-line treatment for cancer.  We have a great team and, for the first time, the funds to execute our plans.

We have also advanced with the very rapid development of our investigational treatment for H1N1 hospitalized patients.  This treatment is based on our LEAPS technology which allows us to direct an immune response outcome.  During the height of the H1N1 wave in the fall of 2009 we worked as fast as possible to move into clinical trials for this new investigational treatment of hospitalized H1N1 patients, as these patients are at serious risk of dying.  We started a study at the Johns Hopkins University School of Medicine in November 2009.  This study needs to enroll 20 H1N1 hospitalized patients and 20 healthy individuals as the control group.  We are waiting for Johns Hopkins to complete the study.  Patient enrollment is completely dependent on patient availability of H1N1 hospitalized patients at Johns Hopkins.

Currently H1N1 does not appear to be a big problem in the US.  However, it continues to infect and kill patients in other places around the world.  Some people think that H1N1 is gone, like Avian Flu and SARS appear to be gone.  H1N1 is different though.  H1N1 has already infected different populations all over the world.  It is the first flu virus that can infect humans throughout all four seasons.  As a flu virus it undergoes rapid mutations.  As such, similar to the normal seasonal flu, we are likely to see H1N1 reappear in a mutated form.  Our greatest fear is that it migh
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