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CASTLE Study Showed Similar Efficacy Between Once-Daily REYATAZ(R) (atazanavir sulfate)/ritonavir and Twice-Daily lopinavir/ritonavir at 48 Weeks in Previously Untreated HIV-Infected Adult Patients
Date:2/6/2008

pride), Camptosar(R) (irinotecan), Crixivan(R) (indinavir), Mevacor(R) (lovastatin), Zocor(R) (simvastatin), rifampin, or St. John's wort (Hypericum perforatum).

People taking REYATAZ should speak with their healthcare provider before taking the following medicines: Viagra(R) (sildenafil), Levitra(R) (vardenafil), Cialis(R) (tadalafil), Vfend(R) (voriconazole), AcipHex(R) (rabeprazole), Nexium(R) (esomeprazole), Prevacid(R) (lansoprazole), Prilosec(R) (omeprazole), Protonix(R) (pantoprazole), Axid(R) (nizatidine), Pepcid AC(R) (famotidine), Tagamet(R) (cimetidine), or Zantac(R) (ranitidine), Advair(R) (fluticasone propionate and salmeterol inhalation powder), Flonase(R) (fluticasone propionate), or Flovent(R) (fluticasone propionate). The above lists of medicines are not complete. The use of all prescriptions and non-prescription medicines, vitamins, herbal supplements, or other health preparations should be discussed with a healthcare provider.

The following side effects or conditions should be reported to a healthcare provider right away:

* A change in the way the heart beats may occur and could be a symptom of

a heart problem.

* Diabetes and high blood sugar may occur in patients taking protease

inhibitor medicines like REYATAZ.

* Yellowing of the skin and/or eyes may occur due to increases in

bilirubin levels in the blood (bilirubin is made by the liver).

* Rash (redness and itching) sometimes occurs in patients taking REYATAZ,

most often in the first few weeks after the medicine is started, and

usually goes away within two weeks with no change in treatment.

* In patients with liver disease, including hepatitis B or C, the liver

disease may get worse when taking anti-HIV medicines like REYATAZ.

* Kidney stones have been reported in patients taking REYATAZ(R)

(atazanavir sulfate). Signs or symptoms of kidney stones include pain


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SOURCE Bristol-Myers Squibb Company
Copyright©2008 PR Newswire.
All rights reserved

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