Navigation Links
Bronchitol Cystic Fibrosis Dose Trial Results Positive
Date:8/11/2008

more, baseline FEV1 of between 40%

and 80% of the predicted normal value or a

decline in FEV1 of 20% or more in the last 12

months for those >80% predicted

Study population Median age: 16 yrs, mean FEV1: 63% predicted

Trial Location Canada and Argentina

Commercial partners None

Primary end points:

Change in FEV1 8.6% increase (139 mls) on 400 mg Bronchitol.

-1.6% on 40 mg (p=0.0006). 4.6% on 240 mg,

3.7% on 120 mg

Change in FVC 7.9% increase in FVC on 400 mg vs -0.6% on 40 mg

(p=0.0004). 3.9% on 240 mg, 1.5% on 120 mg

Secondary end points:

Other lung function 11.9% increase in MMEF on 400 mg (vs -0.3% on 40

measures; mg, change did not reach significance)

CF Questionnaire Improved 6.3 points on 400 mg vs -0.2 on 40 mg

Safety/adverse events No serious adverse events on 400 mg Bronchitol

Forward-Looking Statements

The statements contained in this media release that are not purely historical are forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934, as amended. Forward-looking statements in this media release include statements regarding our expectations, beliefs, hopes, goals, intentions, initiatives or strategies, including statements regarding the potential for Aridol and/or Bronchitol. All forward-looking statements included in this media release are based upon information available to us as of the date hereof, and we assume no obligation to update any such forward-looking statement as a result of new information, future events or otherwise. We cannot guarantee that any product candidate will receive FDA or other regulatory approval or th
'/>"/>

SOURCE Pharmaxis Ltd
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Pharmaxis Long-Term Safety Study of Bronchitol Completes
2. Pharmaxis Establishes Named Patient Program for Bronchitol
3. Pharmaxis Concludes Special Protocol Assessment with FDA for Bronchitol Phase 3 Trial
4. Promising Cystic Fibrosis Compound on Track for Development
5. Symbollon Pharmaceuticals, Inc. Evaluates the Clinical Effects of IoGen(TM) on Fibrocystic Breast Disease
6. Pediatric Pulmonary Expert Comments on Study of Lung Transplants for Cystic Fibrosis
7. Cystic Fibrosis Foundation Reports Upward Trend for Key Health Outcomes
8. Cystic Fibrosis Foundation Announces Positive Early Results for Phase 2 Clinical Trial of VX-770 - an Oral Compound to Treat CF
9. Lung Transplants in Cystic Fibrosis Patients With Life-Threatening Bacteria Sparks Debate at ISHLT Meeting
10. PTC Therapeutics Announces Data Supporting Cough Frequency as a New Outcome Measure in Evaluating Treatments for Cystic Fibrosis
11. PTC Therapeutics Announces Data from Additional Clinical Studies of PTC124 in Cystic Fibrosis Confirming Activity
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/19/2014)... You,re visiting the dentist for what you ... or she says you need a root canal. Though ... have several questions and feel apprehensive about your upcoming ... nothing to worry about. The Pennsylvania Dental Association (PDA) ... anxiety the public may have surrounding this common procedure ...
(Date:12/19/2014)... , Dec. 19, 2014 In ... research and marketing communication tools are essential for ... competitive – consequently consumers, desires, preferences, and unmet ... environment, market research groups across all industries are ... communication tools. However, the adoption of new market ...
(Date:12/19/2014)... --Research and Markets ( http://www.researchandmarkets.com/research/942kh3/micro_market ) ... Market Monitor: North American Dermatology Diagnostic Devices Market" ... http://photos.prnewswire.com/prnh/20130307/600769 Cosmetic surgeries ... resulted in fueling the overall demand of the ... these dermatology devices is to assist in identifying ...
Breaking Medicine Technology:Root Canals Have Become More Routine 2Study Uncovers New Tools and Techniques for Understanding Consumer Decision Making 2Micro Market Monitor: North American Dermatology Diagnostic Devices Market 2Micro Market Monitor: North American Dermatology Diagnostic Devices Market 3
...  GeoVax Labs, Inc. (OTCQB/OTCBB: GOVX), a biotechnology company that ... financial results for the three months ended March 31, ... are delighted with recent developments that have strengthened and ... Board David Dodd. "Our Phase 1/2 therapeutic vaccine trial ...
... 15, 2012  San Diego based neurosurgeon, Dr. Justin M. Brown, ... School of Medicine, has implemented a procedure that helps patients ... and brain injuries, strokes, and other forms of paralysis. ... function after nerve trauma of the upper and lower extremities ...
Cached Medicine Technology:GeoVax Labs Reports 2012 First Quarter Financial Results 2GeoVax Labs Reports 2012 First Quarter Financial Results 3GeoVax Labs Reports 2012 First Quarter Financial Results 4GeoVax Labs Reports 2012 First Quarter Financial Results 5GeoVax Labs Reports 2012 First Quarter Financial Results 6San Diego Based Neurosurgeon Offers Groundbreaking Treatment to Restore Function for People Suffering from Mobility Inhibiting Paralysis 2
(Date:12/22/2014)... As part of a company-wide commitment ... San Diego and surrounding areas, Golden Care ... team with ongoing online training courses. , Online ... by Caregiverlist®. Caregiverlist® is “the premiere service ... reliable eldercare options, highest quality ratings and outstanding ...
(Date:12/22/2014)... 2014 Coral Gables is preparing to welcome ... Troopers, with its new clinic location set to open in ... hassle out of dealing with this common childhood parasite by ... two salon clinic locations in South Florida, or in the ... decision to expand developed naturally out of the demand for ...
(Date:12/22/2014)... SC (PRWEB) December 22, 2014 On ... was joined by Pastor Gordon Cashwell for an episode ... Deierlein asks Gordon, “Why is it so important to ... of Jesus?” Cashwell replies, “We all should respect who ... country was founded on Christian beliefs. That means that ...
(Date:12/22/2014)... Dec. 19, 2014 (HealthDay News) -- U.S. and state ... caramel apples that has killed at least four people ... should not eat any commercially produced, prepackaged caramel apples ... Disease Control and Prevention said in a news release. ... people had been infected with the outbreak strains of ...
(Date:12/22/2014)... NY (PRWEB) December 22, 2014 ... stronger than ever, having invested more than $5 ... service members, veterans and their families. , This ... nearly a dozen nonprofits, helping with: veteran entrepreneurship; ... scholarships; and life-coaches for severely injured veterans. , ...
Breaking Medicine News(10 mins):Health News:Golden Care Partners with Nationally Recognized Caregiver Training Service 2Health News:Professional In-Home All-Natural Lice Removal Service Expands to Coral Gables and surrounding areas. 2Health News:My Positive Perspective Celebrates Christmas With an Event to Celebrate the Birthday of Jesus 2Health News:CDC Warns of Listeria Danger From Caramel Apples 2Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 2Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 3Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 4Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 5Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 6Health News:Bob Woodruff Foundation Poised to Reach More Vets Thanks to Banner Year 7
... OME ), the nation,s leading producer of Omega-3 fish ... of $12.1 million,($0.72 a share) for the fiscal year ... million ($0.19 a share) for the year ended December ... year ended December 31, 2007, the Company had revenues ...
... Omega 3 and Turmeric ... Supplement, ... introduce the latest addition to their family of joint,relief products, which can ... anti-inflammatory formula containing Omega 3 and,Turmeric for double strength joint relief., ...
... largely driven by new cases among gay, bisexual men, CDC ... seventh year in a row, rates of syphilis infection have ... gay and bisexual men, according to a new federal report. ... primary and secondary syphilis -- the earliest and most infectious ...
... The following,is being issued by the Foundation for ... consumer advocate will speak out against proposed legislation ... bars the sharing of private,medical information without a ... by deeming what amounts to marketing material to ...
... Pediatrics has been awarded a five-year, $2.1 million grant ... Development, part of the National Institutes of Health (NIH), ... members embark on research careers. , The grant renews ... resulted in the training of 26 UI clinician-scientists in ...
... an improvement in health-related quality of life, ... March 12 Naturopathic care is more,cost-effective than ... low-back pain, according to a study in the ... Medicine, a peer-reviewed,medical journal published by InnoVision Health ...
Cached Medicine News:Health News:Omega Protein Reports 2007 Results 2Health News:Omega Protein Reports 2007 Results 3Health News:Omega Protein Reports 2007 Results 4Health News:Omega Protein Reports 2007 Results 5Health News:The Makers of Conquer HA(TM) Launch All-Natural Double Strength Anti- Inflammatory Formula 2Health News:U.S. Syphilis Rate Grows for 7th Year in Row 2Health News:U.S. Syphilis Rate Grows for 7th Year in Row 3Health News:Consumer Advocate Speaks Out Against Bill Allowing Invasions of Medical Privacy; Author Received $21k from Bill Benefactors 2Health News:Consumer Advocate Speaks Out Against Bill Allowing Invasions of Medical Privacy; Author Received $21k from Bill Benefactors 3Health News:Consumer Advocate Speaks Out Against Bill Allowing Invasions of Medical Privacy; Author Received $21k from Bill Benefactors 4Health News:Consumer Advocate Speaks Out Against Bill Allowing Invasions of Medical Privacy; Author Received $21k from Bill Benefactors 5Health News:$2.1 million NIH grant advances U-Iowa child health research 2Health News:$2.1 million NIH grant advances U-Iowa child health research 3Health News:Study Finds Naturopathic Care for Chronic Low-Back Pain to be Efficacious, Cost-Effective 2
... these recommendations with the exceptional design and ... resulted in numerous improvements, such as:, ... holder for hassle-free storage , The system ... a flick of the lever, making transportation ...
The S4 Spinal System has quickly gained a reputation for being the next generation in pedicle screw systems because of its exceptionally small size and high biomechanical strength....
... Diagnostics is a clinical reference ... treatment and monitoring of hemostatic ... a collaboration of four laboratory ... defined vision to deliver customizable ...
All-natural porcine collagen can be used in open or laparoscopic placement....
Medicine Products: