Navigation Links
Broad Patent Protection Granted for iBio Immunomodulator
Date:5/8/2012

ongoing tests will provide additional data about the further extent to which prolonged immunity is conferred by the iBioModulator technology. On the strength of results obtained to date, iBio has broadened its commercial program to include additional vaccine applications for preclinical evaluation.

Among the positive tests completed to demonstrate the ability of the iBioModulator platform to improve the performance of vaccines are the following:

  • An iBioModulator-Pfs 25 antigen malaria vaccine candidate in advanced pre-IND testing elicited transmission blocking activity at lower doses and for a longer period of time following immunization compared to a vaccine candidate containing the antigen alone.
     
  • Therapeutic HPV (human papilloma virus) vaccine candidates constructed with iBioModulator provided superior protection from HPV-16 E7-induced tumors and extended survival in a mouse model when compared with vaccination with native E7 protein alone. Effective therapeutic vaccination to treat HPV-induced cancer has been a long-desired but difficult to achieve objective of healthcare professionals. The iBioModulator platform offers a new and promising approach to addressing this important goal.
     
  • iBioModulator has been used as a fusion to express peptide or protein domain antigens in a number of other successful vaccine candidates, including those for plague and anthrax.
  • The iBioModulator also has been used by scientists at iBio, Inc.'s research and development partner, the Fraunhofer USA Center for Molecular Biotechnology, to improve the solubility and stability not only of recombinant vaccine antigens, but other proteins as well.  Ongoing studies will include evaluation of the benefits of using the iBioModulator in the development and production of therapeutic product candidates.

    iBio plans to offer the benefits of the iBioModulator platform to collaborators and licensees of product candidates init
    '/>"/>

    SOURCE iBio, Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4

    Related medicine technology :

    1. Olympus Broadens Portfolio With a Suite of New Single-Use Aspiration Needles
    2. Ethicon Endo-Surgery Receives 510(k) Clearance for New ENSEAL® G2 Curved and Straight Tissue Sealers Line -- Broadest Range of Advanced Bipolar Tissue Sealers Available for Open and Minimally Invasive Surgery
    3. U.S. Soldiers and Veterans at Home and Abroad Touched by Lifesaving Products From Philips Healthcare
    4. New Data From REALISTIC Study Showed Cimzia® (certolizumab pegol) Provided Rapid and Sustained Efficacy, Over 28 Weeks, in a Broad Population of Patients With Moderate to Severe Rheumatoid Arthritis (RA) Including Those Who Discontinued Prior Anti-T
    5. IRIDEX Launches New MicroPulse™ Module Targeting the Broad Ophthalmology Laser Photocoagulation Market
    6. ACT Secures First Patent for Generating Hemangioblast Cells to Treat a Broad Spectrum of Vascular and Hematopoietic Disorders
    7. Boehringer Ingelheim Broadens Its Breast Cancer Clinical Trial Program for the Investigational Compound Afatinib
    8. HYCOR Broadens Diagnostic Offerings, Announces Agreements to License Biomarkers for Celiac Disease and Rheumatoid Arthritis
    9. InspireMD Broadens Global Distribution Network; Signs Distributor for the Russian Federation
    10. Spectros Corporation Introduces Continuum®, a Broadband Infrared Sensor for Brain and Gut Oximetry
    11. Ethicon Endo-Surgery to Showcase Broadest Spectrum of Innovative Bariatric Surgical Options, Physician Best Practices and Mobile/Web-Based After-Care Patient Programs at ASMBS
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:1/15/2014)... YORK , January 15, 2014 ... Ltd., the exclusive worldwide distributor of highly sophisticated agro-breeding ... on January 7, 2014, the Company,s board of directors ... Weiner as its new member of the board. ...
    (Date:1/15/2014)... 15, 2014  In an unprecedented effort to curb the spread of ... other transport vehicles, an advanced and portable UV germicidal lamp manufactured ... first time. In order to prevent EMS paramedics ... West Palm Beach Fire Rescue is the ...
    (Date:1/15/2014)... Jan. 15, 2014 MultiCell Technologies, Inc. (OTC Bulletin ... provisional patent application concerning composition of matter, biological targets, ... tumor cell death.  This patent application ... stranded RNA molecules (VSRNAs) which interfere with the basic ...
    Breaking Medicine Technology:BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 2BreedIT (OTC: BRDT) Appoints Chemistry and Pharmaceutical Industry Expert Dr. Ben-Zion Weiner to Its Board of Directors 3Superbugs No Longer Ride In Rescue Vehicles 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3
    ... April 28, 2011 The U.S. Food and ... combination with prednisone (a steroid) to treat patients ... received prior docetaxel (chemotherapy). (Logo: ... male sex hormone testosterone stimulates prostate tumors to ...
    ... -- When running a company, school or hotel, we ... which presents us with everything completely and obviously. It ... need exact test data to diagnose properly. Shenzhen Wuzhou ... of equipment for sale including digital and infrared ...
    Cached Medicine Technology:FDA Approves Zytiga for Late-Stage Prostate Cancer 2FDA Approves Zytiga for Late-Stage Prostate Cancer 3Testing With Data to Get a More Convenient Diagnosis 2
    (Date:7/10/2014)... tumor cells captured with a microchip-based device developed at ... Medicine and the MGH Cancer Center can be cultured ... testing. In the July 11 issue of ... cultured cells accurately reflect a tumor,s genetic mutation over ... "We now can culture cells from the blood that ...
    (Date:7/10/2014)... looking to bump up their grade point averages during ... in a library or study hall, but in a ... students who were members of the recreational sports and ... sophomore years had higher GPAs than those who weren,t. ... memberships stayed in school longer. An increase of 3.5 ...
    (Date:7/10/2014)... (July 10, 2014) A research review identifying the ... important first step in the process of developing evidence-based ... a new report published by Neurosurgery ... Neurological Surgeons . The journal is published by ... Wolters Kluwer Health . , Based on ...
    (Date:7/10/2014)... as tempting as full-fat equivalents could be heading ... how proteins can replace fats without affecting foodstuffs, ... Engineering and Physical Sciences Research Council (EPSRC), a ... Edinburgh has produced modified proteins that easily break ... behaviour of fats during food manufacture. The proteins ...
    (Date:7/9/2014)... researchers reveal that sudden, acute episodes of low back ... temperature, humidity, air pressure, wind direction and precipitation. Findings ... journal of the American College of Rheumatology (ACR), indicate ... with higher wind speed or wind gusts, but was ... Health Organization (WHO) nearly everyone experiences low back pain ...
    Breaking Medicine News(10 mins):Health News:Cultured CTCs reveal genetic profile, potential drug susceptibility of breast cancer cells 2Health News:Cultured CTCs reveal genetic profile, potential drug susceptibility of breast cancer cells 3Health News:Want a higher GPA in college? Join a gym 2Health News:What's a concussion? Review identifies four evidence-based indicators 2Health News:What's a concussion? Review identifies four evidence-based indicators 3Health News:Great tasting low-fat cheeses and cakes could soon be on the menu 2Health News:Low back pain? Don't blame the weather 2
    ... LIVERMORE, Calif. , Feb. 1 The ... recently featured headline stories about a clinical study that is ... surprised by the attention this study is getting from the ... Officer of Halt Medical, Inc., a medical technology company headquartered ...
    ... could lead to false positives -- adding stress to ... unnecessary follow-up treatment and dietary restrictions. But the ... risk of mental retardation, disability or death outweigh the ... research published today in the February issue of the ...
    ... ... Santen Inc., as its 2010 president. , ... San Francisco (Vocus) -- Ophthalmic Women Leaders (OWL) has appointed ... , , ,Prior to her appointment as president, Gleeson previously served as chair of ...
    ... , ... solution to overcome the obstacle of health insurance. , ... (PRWEB) February 1, 2010 -- EasyToInsureME announces a new solution to ... are very afraid. This past week states like Virginia and Pennsylvania are already making laws ...
    ... A ... ... A report on pedestrian accident statistics released by Elmhurst Hospital Center shows that the number of ... report is being analyzed by New York personal injury attorneys to help their clients., ...
    ... , Feb. 10 Event With Celebrity Panel To Discuss ... The increased scrutiny of the fashion industry and its use of ultrathin ... say that the fashion industry is at least partially responsible for "girls, ... the Girl Scouts of the USA . , The nationwide survey, ...
    Cached Medicine News:Health News:Benefits outweigh risks associated with newborn screening for disorder 2Health News:Ophthalmic Women Leaders (OWL) Names Pamela Gleeson, CFO Of Santen Inc., as 2010 President 2Health News:Recent Shoppers Face Health Insurance Obstacles 2Health News:Recent Shoppers Face Health Insurance Obstacles 3Health News:No Surprise to David Perecman And Other Personal Injury Attorneys, Vehicles Lead All Causes of Injury at New York Hospital 2Health News:No Surprise to David Perecman And Other Personal Injury Attorneys, Vehicles Lead All Causes of Injury at New York Hospital 3Health News:Nationwide Study Finds That Teenage Girls Have Mixed Feelings About the Fashion Industry 2Health News:Nationwide Study Finds That Teenage Girls Have Mixed Feelings About the Fashion Industry 3Health News:Nationwide Study Finds That Teenage Girls Have Mixed Feelings About the Fashion Industry 4
    ... the qualitative differential detection ... antigen and an antigen that ... species of malaria:plasmodium falciparum (P.f), ... (P.o) and Plasmodium malariae (P.m) ...
    For the qualitative detection of antibodies to Treponema pallidum in human serum, plasma and whole blood specimens...
    For the qualitative detection of antibodies to HIV-1 and HIV-2 in human serum, plasma and whole blood specimens...
    ... Philips EP navigator is a new ... confirm the position of any catheter ... detailed 3D cardiac anatomy in the ... help you carry out complex EP ...
    Medicine Products: