Navigation Links
British Midlands University Announces Use of Gene Technology to Fight Lethal Hospital Acquired Infection
Date:1/28/2009

University of Nottingham Scientists Leading Major Study into Lethal 'Super' Strains of C.difficile

CHICAGO, Jan. 28 /PRNewswire/ -- The British Midlands Development Corporation today announced that scientists at The University of Nottingham are leading a major European study to unravel the genetic code of one of the most lethal strains of hospital acquired infections.

The $4.5 million, three-year study will use gene knock-out technology developed in Nottingham to study the function of genes in a 'super' strain of the bacteria Clostridium difficile, to discover why it causes more severe disease, kills more people, is harder to eradicate and more resistant to antibiotics.

It is hoped that the study will lead to better tests to diagnose 'super' strains of C.difficile, more effective treatments and, possibly, even a vaccine to protect against the disease.

Currently, scientists know that the bacteria cause disease by sticking to epithelial cells of the gut lining and releasing two toxins that damage cells leading to the tell-tale symptom of severe diarrhea. However, there is very little known about the ways in which the bacteria operate and why the strain should be more severe than its less virulent cousins.

Leading the study, Professor Nigel Minton in The University of Nottingham's School of Molecular Medical Sciences, said: "These hypervirulent organisms seem to be taking over as the dominant strain in outbreaks and, worryingly, there are only two antibiotics which are still effective against them. There is a very real danger that total resistance may arise, and if that happens then this will become an extremely serious problem.

"The idea behind the study is that we investigate the genomes of the hypervirulent strains and identify their differences to the so-called standard strains. In this way, we should get a clearer picture of the whole range of factor
'/>"/>

SOURCE British Midlands Development Corporation
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. The University of Nottingham in the British Midlands Announces Breakthrough in Parkinsons Disease Research
2. Beactica Announces Fragment-Based Drug Discovery Research Collaboration With GE Healthcare and Uppsala University
3. WaferGen and University of Texas Southwestern Medical Center Establish Biomarker Research Collaboration for SmartChip(TM) Real-Time PCR System
4. University of Kansas Medical Center to Deploy Velos eResearch System-Wide
5. InteRNA Technologies and VU University Medical Center to Develop microRNA-Based Diagnostics and Therapeutics for Cancer
6. Gene Found Activated in 70% of Prostate Cancer Cases, George Washington University Medical Center Scientists Report
7. American College of Cardiology and Center of Excellence for Simulation Research of Western Michigan University (CESR) Partner for in situ Simulation to Improve Team Communication and Door-to-Balloon (D2B) Time
8. Johns Hopkins University Researchers to Clinically Assess Rosetta Genomics miRview(TM) Squamous Assay
9. Queens University Chooses Xceeds Ziplex(R) System for Translational Research
10. deCODE and Radboud University Discover Common Variants in the Human Genome Conferring Risk of Bladder Cancer
11. Boston University and The Center for Human Genetics, Inc. Announce Change in Testing Services
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/27/2014)... CITY , Aug. 27, 2014 Varian Medical ... expand its current Salt Lake City ... underway outside of Utah to ultimately ... the next 20 years. " Utah ... and technical talent, many of whom can be credited with ...
(Date:8/27/2014)... 27, 2014   Los Angeles orthodontics expert, ... to patients who want to make their treatment even ... the OrthoSpaceship, all patients have a powerful tool to ... can be used by most patients with all types ... by using the AcceleDent® Aura system for a few ...
(Date:8/27/2014)... August 27, 2014 According ... Products (Dental Radiology, CAD/CAM, Dental Chairs, Dental Lasers), Current Trends, ... MarketsandMarkets, the global Dental Equipment Market is expected to ... in 2014, growing at a CAGR of 5.7% ... market data tables and 61 figures spread through ...
Breaking Medicine Technology:Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 2Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 3Varian Medical Systems Groundbreaking on Facility Expansion Triggers Influx of New Jobs to Salt Lake 4Los Angeles Orthodontist, Dr. Isaac Hakim, is Now Offering AcceleDent Aura 2Dental Equipment Market Worth $7,138.9 Million by 2019 2Dental Equipment Market Worth $7,138.9 Million by 2019 3
... 22, 2011 Mylan Inc. (Nasdaq: MYL ... of the Mylan Institutional business, has entered a license ... treatment products company, for the exclusive U.S. distribution rights ... Netherlands, has a portfolio that includes products used by ...
... 2011 Auxilium Pharmaceuticals, Inc. (Nasdaq: ... today that they have entered into a long-term ... of XIAFLEX® (collagenase clostridium histolyticum), a novel, first-in-class ... Peyronie,s disease.  Under the terms of the agreement, ...
Cached Medicine Technology:Mylan Announces Exclusive Distribution Partnership with Humeca to Expand Burn and Wound Care Portfolio 2Auxilium Pharmaceuticals, Inc. and Asahi Kasei Pharma Corporation Enter Agreement to Develop, Commercialize and Supply XIAFLEX® In Japan 2Auxilium Pharmaceuticals, Inc. and Asahi Kasei Pharma Corporation Enter Agreement to Develop, Commercialize and Supply XIAFLEX® In Japan 3Auxilium Pharmaceuticals, Inc. and Asahi Kasei Pharma Corporation Enter Agreement to Develop, Commercialize and Supply XIAFLEX® In Japan 4Auxilium Pharmaceuticals, Inc. and Asahi Kasei Pharma Corporation Enter Agreement to Develop, Commercialize and Supply XIAFLEX® In Japan 5Auxilium Pharmaceuticals, Inc. and Asahi Kasei Pharma Corporation Enter Agreement to Develop, Commercialize and Supply XIAFLEX® In Japan 6Auxilium Pharmaceuticals, Inc. and Asahi Kasei Pharma Corporation Enter Agreement to Develop, Commercialize and Supply XIAFLEX® In Japan 7
(Date:8/28/2014)... Baltimore, MD (PRWEB) August 28, 2014 ... has received Diamond level Allergan Privilege Program status ... widely used treatments as Botox, Juvederm, and Voluma. Maryland ... exemplary and prolific use of these treatments. The dermatologists ... in injectable treatments, and are one of the leading ...
(Date:8/28/2014)... 2014 Altec Products, Inc., a ... announced today that they have been awarded the ... of the International Association of Microsoft Channel Partners ... founded in 1994, providing Microsoft Partners with a ... community at large while facilitating mutual growth and ...
(Date:8/28/2014)... Dr. Bryan McIntosh of Bellevue, WA has ... to the tummy tuck cosmetic procedure, leading women through ... and how to recover well afterwards. , The ... also discusses how to have accurate expectations of the ... is as successful as possible. , To learn more ...
(Date:8/28/2014)... August 28, 2014 Dr. Stewart ... young patients throughout the summer that recently headed off ... Education Statistics, over 22 million students will attend ... may spend their time attending classes, studying for exams, ... their risk of eye problems. , Dr. Stewart ...
(Date:8/28/2014)... 2014 Postcard-worthy views, star-laden skies, romantic ... by the beach in your own private bungalow make ... at the Islands of Loreto. , The newest member ... experience in paradise with its romantic Honeymoon package, when ... , “Villa del Palmar at the Islands of Loreto ...
Breaking Medicine News(10 mins):Health News:Maryland Laser Skin and Vein Receives Diamond Status From Allergan 2Health News:Altec and Bond Consulting Services Receive Award from the International Association of Microsoft Channel Partners SoCal Chapter 2Health News:Altec and Bond Consulting Services Receive Award from the International Association of Microsoft Channel Partners SoCal Chapter 3Health News:The Ultimate Guide to the Tummy Tuck Surgery eBook is Released by Dr. Bryan McIntosh 2Health News:Renowned Eye Surgeon Dr. Shofner Shares Five Important Vision Tips For College Students 2Health News:Renowned Eye Surgeon Dr. Shofner Shares Five Important Vision Tips For College Students 3Health News:Honeymoon in Paradise at Villa del Palmar at the Islands of Loreto 2Health News:Honeymoon in Paradise at Villa del Palmar at the Islands of Loreto 3Health News:Honeymoon in Paradise at Villa del Palmar at the Islands of Loreto 4
... Dr. Holmquist Healthcare, LLC Revolutionizes the Future of Bruise ... is pleased to announce the launch of Bruise Relief(TM), ... appearance of bruising, at CVS stores and other fine ... or serum formulation and is designed to super-hydrate the ...
... Attitude could affect care patients might get, experts warn ... percent of those training to be dietitians have positive ... the rest are moderately biased against their prospective patients, ... that future dieticians are not immune to weight bias, ...
... March 5 Yesterday,s Supreme Court ruling against preemption ... research for new therapies, and clearly elevates trial lawyers ... drug safety. The high court has decided that federal ... drug safety, and consequently, a flood of frivolous liability ...
... new study headed by Dr. Tom Feasby, Dean of ... behind other countries in the number of diagnostic imaging ... long wait times. The study,s authors say it is ... , "This study shows there are important deficiencies ...
... more than 3,000 women in the U.S. and southern ... a vaginal microbicide gel for preventing HIV infection in ... Retroviruses and Opportunistic Infections (CROI), one 0.5 % dose ... to cells in the genital tract, was 30% effective. ...
... WORTH, Texas, March 5 LifeSynch, a health ... been selected by Norfolk Southern Corp. ( http://www.nscorp.com ... nutrition, weight management, fitness and health coaching services ... its program called WellNS, Norfolk Southern provides an ...
Cached Medicine News:Health News:Say Goodbye to Unsightly Bruises and Skin Discolorations with Bruise Relief(TM) 2Health News:Bias Against Obesity Is Found Among Future Dietitians 2Health News:Bias Against Obesity Is Found Among Future Dietitians 3Health News:High Court Ruling Against Preemption Hurts Patients, Helps Trial Lawyers 2Health News:Lack of strategies to manage MRI wait lists a key reason for excessive wait times 2Health News:Clinical trial finds microbicide promising as HIV prevention method for women 2Health News:LifeSynch Chosen to Provide Wellness Services to Norfolk Southern 2
The perfect quick consult for the busy cardiologist, The Ultimate Echo Guide puts the most clinically essential information in an easy access format....
... a quick-lookup reference for ECG interpretation ... presents the basics (anatomy and physiology ... system of the heart, basic ECG ... algorithms, emergency medications, and comprehensive information ...
Dx/Rx: Heart Failure has tables and figures that summarize important clinical data and current professional society recommendations and up-to-date information for diagnosis and treatment of Heart Fai...
Topics include: ECG reading, ACLS (all the latest protocols and pearls), CHF, acute MI, cardiac testing, palpitations, pericarditis, arrhythmias, murmurs, athletes, valvular disease, endocarditis, sy...
Medicine Products: