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Breast Cancer Diagnostic and Drug Technologies: Global Markets
Date:8/28/2012

CHOICE OF A DIAGNOSTICS PARTNER 48

HERCEPTEST AND TRASTUZUMAB (HERCEPTIN) 48

NEXT STEPS 49

CHAPTER 5 BREAST CANCER 51

SYNOPSIS 51

TABLE 26 SURVEILLANCE, EPIDEMIOLOGY AND END RESULTS SUMMARY STAGE SYSTEM

FOR BREAST CANCER 52

CLASSIFICATION OF BREAST CANCER 52

TABLE 27 MAIN TYPES OF BREAST CANCER 52

LUMINAL A AND LUMINAL B TYPES 53

HER2 TYPE 53

BASAL TYPE 53

TRIPLE-NEGATIVE BREAST CANCER TREATMENTS IN THE PIPELINE 54

CAUSES, INCIDENCE AND RISK FACTORS 54

SYMPTOMS 55

TABLE 28 BREAST CANCER EVALUATION TESTS 55

BREAST CANCER CAUSES 56

PATHOPHYSIOLOGY 56

TREATMENT 56

TABLE 29 TREATMENT PLAN 56

TABLE 30 HORMONE THERAPY 57

CANCER TREATMENT: LOCAL OR SYSTEMIC 57

TABLE 31 CANCER STAGES 57

PROGNOSIS AFTER TREATMENT 58

TABLE 32 RISK FACTORS OF RECURRENCE AFTER SUCCESSFUL TREATMENT FOR BREAST

CANCER 58

BREAST CANCER TREATMENT GUIDELINES 58

PREVENTION 59

TABLE 33 BREAST CANCER PREVENTION MEASURES 59

TABLE 34 AMERICAN CANCER SOCIETY'S DIETARY GUIDELINES FOR CANCER PREVENTION 59

CHAPTER 6 BREAST CANCER PREVALENCE AND INCIDENCE RATES 61

CANCER INCIDENCE ACROSS THE GLOBE 61

BREAST CANCER GLOBALLY 61

GLOBAL BREAST CANCER STATISTICS 62

TABLE 35 BREAST CANCER INCIDENCE AND MORTALITY GLOBALLY, 2008 (THOUSANDS) 63

FIGURE 1 GLOBAL BREAST CANCER INCIDENCE AND MORTALITY, 2008 (THOUSANDS) 63

GEOGRAPHIC VARIATION IN BREAST CANCER RATES 64

TABLE 36 ESTIMATED GLOBAL INCIDENCE OF BREAST CANCER, 2010–2016 65

FIGURE 2 ESTIMATED GLOBAL INCIDENCE OF BREAST CANCER, 2010–2016 65

TABLE 37 NEW BREAST CANCER CASES BY GEOGRAPHIC REGION, 2009 (THOUSANDS/%) 66

HIGHEST INCIDENCE RATES GLOBALLY 67

TABLE 38 EFFECTIVE EDUCATION AND SCREENING ADVANTAGES IN THE U.K. AND THE

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