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Breast Cancer Diagnostic and Drug Technologies: Global Markets
Date:8/28/2012

N NANOSTRING TECHNOLOGIES 165

AETERNA ZENTARIS TAPS VENTANA FOR COMPANION DIAGNOSTIC 165

MDXHEALTH CLOSES AGREEMENT WITH PFIZER TO IDENTIFY A PREDICTIVE

BIOMARKER FOR PARP INHIBITOR THERAPIES 166

FDA GRANTS ROCHE'S PERTUZUMAB PRIORITY REVIEW 166

ALLIANCES 167

BREAST CANCER DRUG AND DIAGNOSTIC PATENT LANDSCAPE 167

BREAST CANCER DRUGS AND PATENT EXPIRY 167

BREAST CANCER PREDICTIVE DIAGNOSTIC PATENTS 167

RECENT PATENT-RELATED ACTIVITY 168

"WHO OWNS PATIENTS' GENES?" AND PATENT ISSUES 168

MYRIAD GENE PATENT RULING 168

NEW BREAST CANCER PATENT AWARDED TO PHIGENIX 169

GALENA BIOPHARMA STRENGTHENS NEUVAX INTELLECTUAL PROPERTY

POSITION 169

CONCLUSIONS 170

CHAPTER 11 REFERENCES 172

 

LIST OF TABLES

SUMMARY TABLE GLOBAL MARKET FOR PREDICTIVE BREAST CANCER DIAGNOSTIC AND

DRUG TECHNOLOGIES, THROUGH 2016 ($ MILLIONS) 6

TABLE 1 POSSIBLE SIGNS OF BREAST CANCER 10

TABLE 2 DIAGNOSTIC MAMMOGRAM FOR BREAST CANCER 11

TABLE 3 BREAST CANCER GRADES 15

TABLE 4 BIOPSY OR SURGERY SAMPLE TESTING 16

TABLE 5 TESTS USED TO EVALUATE DIFFERENT GENE SETS 17

TABLE 6 IMAGING TESTS THAT DETERMINE IF BREAST CANCER HAS SPREAD 18

TABLE 7 HER2 TESTING AND VARIATIONS 19

TABLE 8 GUIDELINES FOR EARLY DETECTION OF BREAST CANCER IN AVERAGE RISK,

ASYMPTOMATIC WOMEN 25

TABLE 9 BREAST CANCER SCREENING RECOMMENDATIONS BY THE USPSTF 26

TABLE 10 BREAST CANCER PROGNOSTIC FACTORS 30

TABLE 11 BREAST CANCER PREDICTIVE FACTORS 30

TABLE 12 RECURRENCE RATES AT FIVE YEARS IN PATIENTS WITH LYMPH NODES THAT ARE

POSITIVE FOR CANCER (%) 31

TABLE 13 FIVE-YEAR SURVIVAL RATES CORRELATED WITH TUMOR STAGE (%) 31

TABLE 14 PREDICTIVE DIAGNOSTIC FEATURES 32

TABLE 15 CURRENT BIOMARKER TECHNOLOGIES 34

TABLE 16 BIOMARKER USES 35

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