Navigation Links
Brain Waves Show Sound Processing Abnormalities in Autistic Children
Date:11/30/2008

CHICAGO, Dec. 1 /PRNewswire-USNewswire/ -- Abnormalities in auditory and language processing may be evaluated in children with autism spectrum disorder by using magnetoencephalography (MEG), according to a study presented today at the annual meeting of the Radiological Society of North America (RSNA).

"Using MEG, we can record the tiny magnetic fields associated with electrical brain activity," said Timothy Roberts, Ph.D., vice chair of research in the Department of Radiology at Children's Hospital of Philadelphia. "Recorded brain waves change with every sensation, thought and activity. It's like watching a movie of the brain in real time."

Typically used for epilepsy evaluation, MEG can also be used to identify timing abnormalities in the brains of patients with autism.

"We found that signatures of autism are revealed in the timing of brain activity," Dr. Roberts said. "We see a fraction of a second delay in autistic patients."

Autism is a complex developmental disability that affects approximately one in every 150 American children, mostly boys, according to the Autism Society of America. Autism inhibits the brain functions that govern the development of social and communication skills.

For a MEG exam, a helmet that houses magnetic detectors and looks similar to an old-fashioned hair dryer is lowered over the patient's head while the patient remains in a seated position. The helmet analyzes electrical currents from the brain.

For the study, 64 patients, age six to 15, with a diagnosis of autism spectrum disorder were evaluated with MEG. Audio stimulation was introduced to the children in the form of beeps, tones in pairs, vowels or sentences. Sounds were presented at different frequencies and tone pairs in rapid succession, including unusual streams of incongruous tones and vowels. The results were analyzed and compared with the results from a control group of age-matched non-autistic children.

The findings showed that in the children with autism there was a fraction of a second delay in the brain's response while processing the rapid succession sounds and the unusual streams, giving researchers an insight into the dysfunction of the auditory processing system in autistic children.

"This delay in processing certain types and streams of sound may underpin the subsequent language processing and communication impairment seen in autistic children," Dr. Roberts said.

Dr. Roberts predicts that the signatures of autism found in brain activity will become biomarkers to improve classification of the disorder and aid in treatment and therapy planning.

"We hope that in the future these signatures will also be revealed in the infant brain to help diagnose autism and allow earlier intervention," he said.

Co-authors are J. Christopher Edgar, Ph.D., Deborah M. Zarnow, M.D., and

Susan E. Levy, M.D.

Disclosure: This study was funded by the National Institutes of Health and by the Nancy Lurie Marks Family Foundation.

AT A GLANCE

  • Abnormalities in language processing in children with autism can be identified using magnetoencephalography (MEG).
  • The brain's auditory processing system is delayed a fraction of a second in children with autism.
  • Autism affects one in every 150 American children, mostly boys.

Note: Copies of RSNA 2008 news releases and electronic images will be available online at RSNA.org/press08 beginning Monday, Dec. 1.

RSNA is an association of more than 42,000 radiologists, radiation oncologists, medical physicists and related scientists committed to excellence in patient care through education and research. The Society is based in Oak Brook, Ill. (RSNA.org)

Editor's note: The data in these releases may differ from those in the printed abstract and those actually presented at the meeting, as researchers continue to update their data right up until the meeting. To ensure you are using the most up-to-date information, please call the RSNA Newsroom at 1-312-949-3233.

For patient-friendly information on imaging technologies and procedures, visit RadiologyInfo.org.

    Media Contacts: RSNA Newsroom 1-312-949-3233
    Before 11/29/08 or after 12/4/08: RSNA Media Relations 1-630-590-7762
    Maureen Morley Linda Brooks
    1-630-590-7754 1-630-590-7738
    mmorley@rsna.org lbrooks@rsna.org


'/>"/>
SOURCE Radiological Society of North America (RSNA)
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. New Evidence That Brain-Plasticity Based Training has Broad Impact: Improved Cognition in Boomers, Improved Motor Control in Older Adults
2. Senate Told Brain Technology Can Impact Public Policy
3. Long-Term Phase I and Phase I/II Trial Data Continue to Show Striking Improvement in Survival of Brain Cancer Patients Who Receive DCVax(R)-Brain
4. Study Suggests a Possible Way to Offset Chemobrain Memory Loss
5. Cytopia Commences Second Phase II Study in Brain Cancer
6. Neurosciences Institute Discovers Drug Extends Stroke Treatment Time to 24 Hours, Repairs Brain Tissue
7. Lixte Biotechnology Holdings Announces That Novel Compounds Being Developed as Potential Treatments for Brain Tumors Have Positive Activity in a Mouse Model of Human Pancreatic Cancer
8. Findings on Bladder-Brain Link May Point to Better Treatments for Problems in Sleep, Attention
9. Scientists Reveal Roadmap to Brain Health That Can Be Passed Down to Future Generations: Exercise, Omega-3, Folic Acid, Vitamin B6, and Vitamin B12
10. CeNeRx BioPharma Finalizes Plans to Initiate Phase II Trials for Its Novel Antidepressant Agent Tyrima(TM) Using Innovative Brain Imaging Study
11. New Research Provides Evidence that Tea May Improve Attention and Focus, Keep Brain Cells Healthy, & Influence Genetics in Cancer
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ANDOVER, Mass. and SAN CLEMENTE, Calif. ... California -based mobile pulmonary function testing company, is now ... portable PFT devices developed by ndd Medical Technologies , Inc. ... PFT testing done in hospital-based labs.  Thanks to ndd,s EasyOne PRO ... CA , can get any needed testing done in the ...
(Date:6/24/2016)...  Arkis BioSciences, a leading innovator in the ... cerebrospinal fluid treatments, today announced it has secured ... led by Innova Memphis, followed by Angel Capital ... Arkis, new financing will accelerate the commercialization of ... of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... 23, 2016  In a startling report released today, National ... by lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... of how states are tackling the worst drug crisis in recorded ... – Kentucky , New Mexico ... . Of the 28 failing states, three – Michigan ...
Breaking Medicine Technology:
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery ... of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , ... for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... First ... United States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell ... facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive ...
(Date:6/25/2016)... , ... June 25, 2016 , ... On Friday, June ... a Bronze Wellness at Work award to iHire in recognition of their exemplary accomplishments ... of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI Marriott ...
(Date:6/24/2016)... , ... June 24, 2016 , ... Those who have ... these feelings, many turn to unhealthy avenues, such as drug or alcohol abuse, as ... Michigan, has released tools for healthy coping following a traumatic event. , Trauma sufferers ...
(Date:6/24/2016)... ... June 24, 2016 , ... ... Sessions in Dallas that it will receive two significant new grants to support ... as PHA marked its 25th anniversary by recognizing patients, medical professionals and scientists ...
Breaking Medicine News(10 mins):