Navigation Links
Brain Stem Cells Can Be Awakened, Say Schepens Scientists
Date:6/6/2008

Study Findings Promise to help in treatment of brain diseases

BOSTON, June 6 /PRNewswire/ -- Scientists at Schepens Eye Research Institute have identified specific molecules in the brain that are responsible for awakening and putting to sleep brain stem cells, which, when activated, can transform into neurons (nerve cells) and repair damaged brain tissue. Their findings are published online this week in the Proceedings of the National Academy of Science (PNAS).

An earlier paper (published in the May issue of Stem Cells) by the same scientists laid the foundation for the PNAS study findings by demonstrating that neural stem cells exist in every part of the brain, but are mostly kept silent by chemical signals from support cells known as astrocytes.

"The findings from both papers should have a far-reaching impact," says principal investigator, Dr. Dong Feng Chen, who is an associate scientist at Schepens Eye Research Institute and an assistant professor of ophthalmology at Harvard Medical School. Chen believes that tapping the brain's dormant, but intrinsic, ability to regenerate itself is the best hope for people suffering from brain-ravaging diseases such as Parkinson's or Alzheimer's disease or traumatic brain or spinal cord injuries.

Until these studies, which were conducted in the adult brains of mice, scientists assumed that only two parts of the brain contained neural stem cells and could turn them on to regenerate brain tissue -- the subgranular zone (SGZ) of the hippocampus and the subventricular zone (SVZ). The hippocampus is responsible for learning and memory, while the SVZ is a brain structure situated throughout the walls of lateral ventricles (part of the ventricular system in the brain) and are responsible for generating neurons responsible for smell. So scientists believed that when neurons died in other areas of the brain, they were lost forever along with their functions.

In the first study, Chen's team l
'/>"/>

SOURCE Schepens Eye Research Institute
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Data To Be Presented at ASCO Supports Potential of Peregrines Cotara(R) for the Treatment of Brain Cancer
2. St. Jude Finds Young Age May Give Survival Advantage to Children With Certain Brain Tumors
3. BrainCells Inc. Initiates Phase 2 Clinical Trial with BCI-540 for Depression with Anxiety
4. How Big Is Your Brain? Its Size May Protect You from Memory Loss
5. BiPar Sciences Expands Clinical Program for BSI-201, a Novel DNA Repair Inhibitor, in Brain Cancer
6. ALS Therapy Development Institute Signs Collaboration Agreement with the Allen Institute for Brain Science
7. Evotecs EVT 101 Shown to Penetrate the Brain in Man and to Modulate Brain Activity During the Performance of Cognitive Tasks
8. St. Jude Finds Signaling System That Halts the Growth of a Childhood Brain Cancer
9. New Clinical Data Further Supports Chromium Picolinates Role in Enhancing Brain Activity in Older Adults
10. Phase I and Phase I/II DCVax(R)-Brain Data Continues to Show Significantly Improved Survival Rates for Brain Cancer Patients
11. Neuroscientists Offer Hope for Breast Cancer Patients Suffering From Chemobrain
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... 2014 According to a new ... Global Industry Analysis, Size, Share, Growth, Trends and Forecast, ... CAGR of 10.1% from 2014 to 2020. ... are used in the treatment and prevention of various ... other medical disorders. Biological drugs include therapeutic proteins, monoclonal ...
(Date:9/2/2014)... Sept. 2, 2014  For over a decade SafeMinds has ... between vaccines and autism. But at least for one study, ... a statement , William Thompson , Ph.D. acknowledged ... the MMR vaccine to an increased risk of autism in ... same data suggests that African American males have a 340% ...
(Date:9/2/2014)... Calif. , Sept. 2, 2014 ... today an increase in capital and cash advance ... Intuitive Surgical System,s da Vinci Robot. With over ... product, Legal-Bay focuses on providing lawsuit cash advances ... injuries, nerve damage, lacerations to internal organs, burns ...
Breaking Medicine Technology:CAGR of 10.1% Global Biological Drugs Market - Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 to 2020: Report by MarketResearchReports.Biz 2CAGR of 10.1% Global Biological Drugs Market - Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 to 2020: Report by MarketResearchReports.Biz 3CAGR of 10.1% Global Biological Drugs Market - Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 to 2020: Report by MarketResearchReports.Biz 4CAGR of 10.1% Global Biological Drugs Market - Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 to 2020: Report by MarketResearchReports.Biz 5CAGR of 10.1% Global Biological Drugs Market - Industry Analysis, Size, Share, Growth, Trends and Forecast 2014 to 2020: Report by MarketResearchReports.Biz 6CDC vaccine scientist admits wrongdoing. 2CDC vaccine scientist admits wrongdoing. 3da Vinci Lawsuit Settlement Funding Amounts Increased at Legal-Bay Funding 2da Vinci Lawsuit Settlement Funding Amounts Increased at Legal-Bay Funding 3
... Aug. 25 David N. Jonas, Chairman and CEO ... R. Spalding to the company,s Board of Directors. ... Crawford Spalding Group, an advisory and management services firm ... assist companies primarily in the healthcare services industry.  Jonas ...
... Conn., Aug. 25 Biodel Inc. (Nasdaq: BIOD ... with two institutional investors to sell 2,398,200 shares of its ... common stock.  The common stock and warrants are being sold ... common stock and a warrant to purchase one share of ...
Cached Medicine Technology:Biodel to Raise $9.4 Million Through Registered Direct Offering 2Biodel to Raise $9.4 Million Through Registered Direct Offering 3
(Date:9/2/2014)... Fort Lauderdale, Florida (PRWEB) September 02, 2014 ... Joint Commission Accredited teleradiology and telemedicine solutions provider, ... attention with its innovative and technologically advanced services. ... Dar Al Shifa Hospital in Kuwait. , Founded ... hospital in Kuwait, Dar Al Shifa began as ...
(Date:9/2/2014)... A little bit of moodiness now and then ... irritability, sadness, or apathy can be a sign of ... Health Letter. , "Mood-related symptoms can come and ... for long periods, cause significant distress, or interfere with ... Dr. Nancy Donovan, an instructor in psychiatry at Harvard ...
(Date:9/2/2014)... (PRWEB) September 02, 2014 MyRounding, the ... care, has been selected from a group of over ... the 2014 PrIME Digital Health Challenge. The competition will ... another, Tuesday, Sept. 9th at the CSU Denver Atrium ... MyRounding is based in Denver, Colo. The cloud-based, SaaS ...
(Date:9/2/2014)... FL (PRWEB) September 02, 2014 ... that they are gathering content for upcoming episodes ... to air first quarter 2015. , Innovations, hosted ... and exploring today's latest breakthroughs and advancements taking ... series will focus on advancements in biosciences. Biosciences ...
(Date:9/2/2014)... September 02, 2014 With thoughts of ... on the minds of many Washingtonians, it’s easy to ... planners and office managers to be booking their organizations’ ... & Resorts' Washington, DC, area locations are preparing for ... dates available for holiday parties, the space appears to ...
Breaking Medicine News(10 mins):Health News:USARAD Holdings Inc. SECONDOPINIONS.COM® Partners With Prestigious Dar Al Shifa Hospital In Kuwait 2Health News:USARAD Holdings Inc. SECONDOPINIONS.COM® Partners With Prestigious Dar Al Shifa Hospital In Kuwait 3Health News:USARAD Holdings Inc. SECONDOPINIONS.COM® Partners With Prestigious Dar Al Shifa Hospital In Kuwait 4Health News:When a Mood Swing Signals Trouble, From the September 2014 Harvard Health Letter 2Health News:MyRounding Selected for Digital Health Venture Showcase Finals Top Three Startups Awarded $50,000 2Health News:Exciting New Episodes of Innovations with Ed Begley Jr to Air via Discovery Channel 2Health News:Fall in Washington, DC, Is When a Meeting Planner’s Mind Turns to … the Winter Holidays? 2Health News:Fall in Washington, DC, Is When a Meeting Planner’s Mind Turns to … the Winter Holidays? 3Health News:Fall in Washington, DC, Is When a Meeting Planner’s Mind Turns to … the Winter Holidays? 4Health News:Fall in Washington, DC, Is When a Meeting Planner’s Mind Turns to … the Winter Holidays? 5
... matter, eating something that,s considered healthy might simply lead us ... new study in the Journal of Consumer Research . ... Chicago) examined external controls in the domain of healthy eatingsuch ... consumers who eat healthy meals in a cafeteria that only ...
... Care bill in the midnight hours "the largest expansion of the federal government in American history and a tragic mistake. Elections have consequences. The only remedy for this ... ... ... ...
... , March 22 Children,s Health Fund (CHF) ... and applauds Congress for its steadfast commitment to this momentous ... is a fundamental right, especially for children.  The action taken ... for the health and well-being of all children in this ...
... Bunker Hill Community College will dedicate a new Health & Wellness Center on Tuesday, March ... at the event will be Massachusetts Lieutenant Governor Tim Murray , State Representative Eugene L. O,Flaherty , ... ... , ...
... deaf, might you still be able to hear the sound? ... MD, director of the Adult Cochlear Implant Program at the ... people who have diseases and disorders related to hearing, swallowing, ... investigational device that will enable people who have lost hearing ...
... ... efficient solution to reduce the costs for building a web site. Website Realizer 1.0 provides ... line of code. , ... March 22, 2010 -- Adritech Software has announced the launch of Website Realizer , ...
Cached Medicine News:Health News:Healthy food makes consumers feel hungrier when choices are limited 2Health News:Bauer Says the Only Remedy for the "Tragic Mistake" of the Health Care Vote Is at the Ballot Box 2Health News:Statement by Irwin Redlener, MD, President, Children's Health Fund on Passage of a Health Care Reform Package by the House 2Health News:Statement by Irwin Redlener, MD, President, Children's Health Fund on Passage of a Health Care Reform Package by the House 3Health News:BHCC Dedicates 48,000-Square-Foot Health & Wellness Center 2Health News:BHCC Dedicates 48,000-Square-Foot Health & Wellness Center 3Health News:UC center chosen to study auditory brain stem implants 2Health News:UC center chosen to study auditory brain stem implants 3Health News:Adritech Software Releases Website Realizer, a Website Builder to Create Websites without Any Programming Knowledge 2
The BacT/Alert 3D Select Link is a state of the art, automated microbial detection system that integrates blood, sterile body fluid and mycobacteria culturing. This system is useful when patient data...
The Vitek 2 is a fully automated bacteriology system that performs bacterial identification and susceptibility testing analysis using a standard inoculum. It detects resistance and helps combat bacte...
... completely automated instrument that offers Rapid results ... hour same day turnaround), random or batch ... is used for bacterial and yeast identification, ... has a complete data management system. It ...
IDS Rapid Yeast Plus, a microbial identification system....
Medicine Products: