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Boston Scientific Welcomes Publication of HORIZONS AMI Trial Results in New England Journal of Medicine
Date:5/6/2009

dary efficacy endpoint of binary restenosis, from 22.9 percent among lesions in the BMS group to 10.0 percent among lesions in the DES group (p<0.001). This restenosis benefit was due to a significant reduction of in-stent late loss for DES lesions compared to BMS (0.41 +/- 0.64 mm vs. 0.82 +/- 0.70 mm, p<0.001).

The primary safety endpoint of MACE at one year was comparable among DES and BMS patients (8.1% vs. 8.0%, respectively, p=0.92), with comparable individual rates of death, repeat heart attack, stroke and stent thrombosis between the two groups through 12 months of follow-up, which persisted even after correction for any measured baseline differences.

The TAXUS Express Stent and the Express Stent are not specifically indicated by the U.S. Food and Drug Administration for use in patients with AMI.

About Boston Scientific

Boston Scientific is a worldwide developer, manufacturer and marketer of medical devices whose products are used in a broad range of interventional medical specialties. For more information, please visit: www.bostonscientific.com.

Cautionary Statement Regarding Forward-Looking Statements

This press release contains forward-looking statements within the meaning of Section 21E of the Securities Exchange Act of 1934. Forward-looking statements may be identified by words like "anticipate," "expect," "project," "believe," "plan," "estimate," "intend" and similar words. These forward-looking statements are based on our beliefs, assumptions and estimates using information available to us at the time and are not intended to be guarantees of future events or performance. These forward-looking statements include, among other things, statements regarding clinical trials, regulatory approvals, and product performance. If our underlying assumptions turn out to be
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