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Boston Scientific ION™ Platinum Chromium Stent System Demonstrates Strong Performance in Analysis of PERSEUS and TAXUS ATLAS Clinical Trial Data
Date:4/3/2011

02).  A numerically lower but not statistically different rate of target vessel revascularization (TVR) was also observed in favor of the ION Stent (6.5 percent vs. 8.8 percent, p=0.12), supported by significantly lower late loss at nine months (0.33 plus/minus 0.52 mm vs. 0.42 plus/minus 0.56 mm, p=0.04).

"These results reinforce the relative clinical benefits of the PtCr Stent Series we have observed through physician experience in Europe and other approved markets," said Hank Kucheman, Executive Vice President and Group President, Cardiology, Rhythm and Vascular for Boston Scientific.  "The ION Stent's advanced alloy, stent architecture and delivery system, coupled with a proven drug and polymer combination, provide interventional cardiologists with improved acute performance in treating patients with coronary artery disease."

The ION Stent System features an innovative PtCr alloy and new stent design to offer greater strength, enhanced deliverability and exceptional visibility.  The thin-strut stent is designed for improved conformability, minimal recoil, and uniform lesion coverage and drug distribution.  The advanced low-profile delivery system facilitates precise delivery of the stent across challenging lesions.

The PERSEUS clinical program compared the ION (TAXUS Element) Stent to prior-generation Boston Scientific stents in more than 1,600 patients in two parallel trials at 90 centers worldwide.  The PERSEUS Workhorse trial reported 12-month results in March 2010, demonstrating positive safety and efficacy outcomes in workhorse lesions for the ION Stent System compared to the TAXUS® Express2® Stent System.  The TAXUS ATLAS program compared patients with de novo coronary lesions treated with the TAXUS Liberte Stent to a historical case-matched TAXUS Express® Stent control group.

In the U.S., the TAXUS Element Stent System will be commercialized as the ION™ Paclitaxel-Elutin
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SOURCE Boston Scientific Corporation
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