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Boston Scientific Completes Clinical Trial Enrollment for Third-Generation Drug-Eluting Stent
Date:10/8/2008

PERSEUS clinical program to evaluate TAXUS(R) Element(TM) Platinum Chromium

Stent

NATICK, Mass., Oct. 8 /PRNewswire-FirstCall/ -- Boston Scientific Corporation (NYSE: BSX) today announced that it has completed enrollment in the PERSEUS trial, designed to evaluate the Company's third-generation TAXUS(R) Element(TM) paclitaxel-eluting coronary stent. The PERSEUS clinical program has enrolled nearly 1,500 patients at 100 U.S. and international centers since July 2007, and will compare the TAXUS Element Stent to the prior-generation TAXUS(R) Express2(TM) Stent marketed in the United States since 2004. The Company plans to develop additional versions of the Element platform, including next generations of a bare-metal stent and an everolimus-eluting PROMUS(R) Element stent system.

"We are pleased to reach this important milestone in the development of our third-generation drug-eluting stent, at a time when most companies are still introducing their first-generation stents in the U.S.," said Keith Dawkins, M.D., Senior Vice President and Associate Chief Medical Officer for Boston Scientific. "Boston Scientific is the only company to offer interventionalists a choice between two different drugs in a DES platform. The advanced Platinum Chromium Alloy and new balloon catheter offered in the Element system will further strengthen our deep portfolio of coronary stent technologies."

The Element Stent platform features the proprietary Platinum Chromium Alloy, designed specifically for stents. This alloy, coupled with an innovative new stent architecture, is designed to enable thinner struts for increased flexibility, a lower profile, and improved radial strength, recoil, and radiopacity. In addition,
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