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Boston Scientific Carotid Artery Stenting Trials Produce Positive Three-Year Results
Date:10/23/2007

NATICK, Mass. and WASHINGTON, Oct. 23 /PRNewswire-FirstCall/ -- Boston Scientific Corporation (NYSE: BSX) today announced positive three-year results from its CABERNET and BEACH carotid artery stenting clinical trials. The studies evaluated the effectiveness of stenting with embolic protection for patients at high risk for carotid endarterectomy (CEA), the surgical treatment for carotid artery disease. The three-year CABERNET and BEACH results were presented by L. Nelson Hopkins, M.D., Chairman of Neurosurgery, Department of Neurosurgery, State University of New York, Buffalo, NY, at the annual Transcatheter Cardiovascular Therapeutics (TCT) scientific symposium in Washington, D.C.

Dr. Hopkins reported that the CABERNET major stroke rate was 1.3% at 30 days and 2.8% at three years. The reported BEACH major stroke rate was 1.7% at 30 days and 8.1% at three years. According to the three-year CABERNET data, the ipsilateral stroke rate (a stroke occurring on the treated side of the neck) was 2.9% at 30 days and by three years had only increased to 4.9%. In the BEACH trial, the ipsilateral stroke rate was 3.1% at 30 days and by three years had only increased to 7.7%.

"The three-year results suggest not only an immediate benefit for patients treated with Boston Scientific's NexStent(R) Carotid Stent and FilterWire EZ(TM) Embolic Protection System, but also a longer-term benefit in reducing the incidence of stroke over time," said Dr. Hopkins, Co-Principal Investigator of the CABERNET and BEACH clinical trials. "In particular, the CABERNET three-year trial results are very encouraging and continue to demonstrate the long-term efficacy and durability associated with Boston Scientific's NexStent Carotid Stent when u
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