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Bone Mineral Content Continues to Increase in Obese Adolescents During Weight Loss
Date:2/1/2008

nd of the study.

When looking at each subject's bone mineral content, adjusted for their height, the researchers noticed that bone mineral content in the arms and legs increased less than would be expected with growth while the lumbar spine content increased more than expected. These changes in bone mineral content were largely explained by changes in the amount of fat and muscle in the body during the intensive weight loss program.

"As obesity treatment during adolescence becomes more frequent, it is important to understand the role of weight loss on bone health during this critical period," Dr. Stettler added.

This study was supported by the National Institutes of Health, the General Clinical Research Center at Children's Hospital, Knoll Pharmaceutical and Abbott Laboratories.

Dr. Stettler's coauthors were: Robert I. Berkowitz, M.D., chief of child and adolescent psychiatry at Children's Hospital; Joanna Cronquist of Children's Hospital; Justine Shults of the Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine; Thomas A. Wadden, of the Weight and Eating Disorders Program at the University of Pennsylvania School of Medicine; and Babette S. Zemel, Ph.D.; and Mary B. Leonard, M.D. both of Children's Hospital.

About The Children's Hospital of Philadelphia: The Children's Hospital of Philadelphia was founded in 1855 as the nation's first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children's Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking third in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 430-bed hospital recognition as a leading advo
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SOURCE The Children's Hospital of Philadelphia
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