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Boehringer Ingelheim to present new data at ASCO annual meeting regarding its investigational compound afatinib in EGFR-mutation positive patients with advanced NSCLC
Date:5/25/2011

ns. Mutual cooperation and respect, as well as environmental protection and sustainability, are intrinsic factors in all of Boehringer Ingelheim's endeavors.

In 2010, Boehringer Ingelheim posted net sales of approximately $16.7 billion (about 12.6 billion euro) while spending almost 24% of net sales in its largest business segment, Prescription Medicines, on research and development.

For more information, please visit http://us.boehringer-ingelheim.com and follow us on Twitter at http://twitter.com/boehringerus.

References

  1. Janjigian YY et al.  Activity and tolerability of afatinib (BIBW 2992) and cetuximab in NSCLC patients with acquired resistance to erlotinib or gefitinib.  Abstract 7525, poster presentation at 2011 Annual Meeting of the American Society of Clinical Oncology, Chicago, June 6, 2011.  
  2. Sharma SV et al. Epidermal growth factor receptor mutations in lung cancer.  Nat Rev Cancer. 2007;7(3):169-181.
  3. Keedy V et al.  American Society of Clinical Oncology Provisional Clinical Opinion: Epidermal Growth Factor Receptor (EGFR) Mutation Testing for Patients With Advanced Non–Small-Cell Lung Cancer Considering First-Line EGFR Tyrosine Kinase Inhibitor Therapy.  J Clin Oncol. 2011 April.
  4. National Comprehensive Cancer Network.  Non-Small Cell Lung Cancer Clinical Practice Guidelines.  January 2011.
  5. Riely GJ et al.  Clinical course of patients with non-small cell lung cancer and epidermal growth factor receptor exon19 and exon 21 mutations treated with gefitinib or erlotinib.  Clin Cancer Res. 2006 Feb 1;12(3 Pt 1):839-44.
  6. Gazdar AF.  Activating and resistance mutations of EGFR in non-small-cell lung cancer:  role in clinical response to EGFR tyrosine kinase inhibitors. Oncogene. 2009;
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