Navigation Links
Boehringer Ingelheim Enrolls First Patients in Pivotal Phase 3 Interferon-Free Hepatitis C Trial Program
Date:1/17/2013

to stay on treatment, which is imperative to achieve the ultimate goal of a virologic cure," said lead study investigator Christoph Sarrazin , M.D., Professor of Medicine at the Johann Wolfgang Goethe University Hospital in Frankfurt, Germany. "I'm pleased the trial design includes a diverse population of genotype-1b patients, particularly those with liver cirrhosis, reflecting the types of patients we see very frequently in clinical practice."

Boehringer Ingelheim Interferon-free Phase 3 Trial Designs
The Phase 3 trial program includes two pivotal studies:
HCVerso 1
This Phase 3 study will enroll treatment-naive patients infected with HCV GT-1b. Patients will be randomized (1:1) into two treatment arms. A third, open-label arm will enroll cirrhotic patients.

  • Group 1: 24 weeks of BI 207127 600mg BID + faldaprevir 120mg QD + RBV
  • Group 2: 16 weeks of BI 207127 600mg BID + faldaprevir 120mg QD + RBV followed by an additional 8 weeks of placebo
  • Group 3 (patients with compensated liver cirrhosis): 24 weeks of BI 207127 600mg BID + faldaprevir 120mg QD + RBV

HCVerso 2
This Phase 3 study will enroll treatment-naive patients infected with HCV GT-1b, and includes patients who are eligible or ineligible for interferon. Patients will be randomized (1:1) into two treatment arms. A third, open-label arm will enroll cirrhotic patients.

  • Group 1: 24 weeks of BI 207127 600mg BID + faldaprevir 120mg QD + RBV
  • Group 2: 8 weeks of placebo followed by 16 weeks of BI 207127 600mg BID + faldaprevir 120mg QD + RBV
  • Group 3 (patients with compensated liver cirrhosis): 24 weeks of BI 207127 600mg BID + faldaprevir 120mg QD + RBV

Data from the HCVers
'/>"/>

SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Boehringer Ingelheim Presents New Phase II Data for Volasertib in Adult Patients with AML
2. Boehringer Ingelheim Announces Equine Research Awards
3. Phase 2b Data of Boehringer Ingelheims Interferon-Free Hepatitis C Treatment Show Viral Cure Achieved in Up to 85% of Treatment-Naive Patients
4. Whistleblowers extraordinary efforts helped win $95 million settlement with Boehringer Ingelheim
5. Boehringer Ingelheim announces afatinib expanded access program (EAP) for patients with EGFR mutation-positive advanced NSCLC
6. Boehringer Ingelheim and Lilly introduce the My Well Planner Lifestyle Improvement Program for Adults with Type 2 Diabetes
7. Lilly and Boehringer Ingelheim Present Data at the 72nd American Diabetes Association Scientific Sessions® from Phase II Studies Comparing Investigational Novel Basal Insulin to Insulin Glargine
8. Boehringer Ingelheim Presents First Data for Tiotropium in Adolescents with Moderate Persistent Asthma
9. Results of Phase II Study of Boehringer Ingelheims Investigational Bronchodilator for COPD Presented at 2012 ATS International Conference
10. Boehringer Ingelheim to present pivotal Phase III results for afatinib in first-line treatment of EGFR mutation-positive NSCLC at ASCO 2012
11. New Data to be Presented at the Annual American Thoracic Society International Conference Demonstrates Depth of Boehringer Ingelheim Respiratory Research Pipeline
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/24/2014)... LEXINGTON, Mass. , Dec. 23, 2014 /PRNewswire/ ... GEVA ), a biopharmaceutical company developing therapeutic products ... European Medicines Agency (EMA) of the Marketing Authorization ... The EMA recently granted the company,s request for ... the EMA,s regulatory review time.   ...
(Date:12/24/2014)... 2014  Lockton Dunning Benefits, the ... the addition of Vice President Kim Foerster ... Pharmacy Consulting team, Excelsior Solutions. ... to the position.  Most recently, she worked as ... Specialty Pharmacy, where she has held various managerial ...
(Date:12/24/2014)... 23, 2014 Tianyin Pharmaceutical Co., Inc. ... in patented biopharmaceutical, modernized traditional Chinese medicine (mTCM), ... announced that the Company achieved the Public Notice ... (GMP) certificate of TPI,s Qionglai Facility (QLF) from ... public notice period is a significant procedure of ...
Breaking Medicine Technology:Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 2Synageva BioPharma Announces Sebelipase Alfa Marketing Authorization Application Validated By The EMA 3Kim Foerster Joins Lockton Companies 2TPI QLF Achieved Public Notice Status of GMP Certification 2TPI QLF Achieved Public Notice Status of GMP Certification 3
(Date:12/25/2014)... Recently, Dylan Queen, a famous online company supplying women’s ... discounted prom dresses, most of which are priced under ... company, the promotion is valid until Jan. 22, 2015; ... UK market. , The prom dresses in this new ... A-line strapless, empire strapless chiffon, one shoulder, floor-length, V-neck ...
(Date:12/25/2014)... California (PRWEB) December 25, 2014 Helen ... home in Woodland Hills, California after an 8 year ... away on Christmas Eve evening in her home in ... aggressive metastatic breast cancer. , As ... over forty years, she pioneered and championed many of ...
(Date:12/25/2014)... THURSDAY, Dec. 25, 2014 (HealthDay News) -- The risk ... the holidays, so you need to be extra cautious, ... Day, we see a significant increase in patients coming ... at the Suffolk County Volunteer Firefighters Burn Center of ... celebrations should be full of joy, but if not ...
(Date:12/25/2014)... AngelWeddingDress.com tries its best to translate ... Today, the business has introduced its new collection of ... promotion. , The new prom outfits are guaranteed to ... lover. They are specially designed for 2015. Anyone who ... should visit its website before Jan. 26, 2015, the ...
(Date:12/25/2014)... 2014 Residents at Abernethy ... showed their generous spirit by providing holiday gifts ... Parenting Network- Grandparents Raising Grandchildren program. , Following ... the largest Christmas tree on the campus of ... residents of the Abernethy Village Association (AVA). Each ...
Breaking Medicine News(10 mins):Health News:Dylan Queen: Cheap Prom Dresses for the UK Market 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 2Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 3Health News:RP International founder, Helen Harris Dies on Christmas Eve Just Hours Before Her Holiday Television Broadcast to Raise Funds to Cure Blindness was Broadcasted Nationally 4Health News:Don't Let Burns Mar Your Holidays 2Health News:Angelweddingdress 2015 Prom Dresses Online Now 2Health News:Retirement Community Residents Make Impact During Holiday Season 2
... February is Heart ... … while having fun, too. , ... Los Angeles (Vocus) January 25, 2010 -- Every year, over 40,000 American women die ... to be one of them! , , , , ,February is Heart Health Month. Self-care ...
... ... hablan de disparidades e instan a los grupos de socorro a que tengan en ... ... del pasado indica que probablemente las mujeres y los niños en Haití no estén ...
... Center at the University of California, San Diego and ... between county hospitals and private providers. Patients treated in ... patients treated in private facilities tend to receive radiation ... the journal Cancer on January 25. ...
... Children who are mixed-handed, or ambidextrous, are more likely ... childhood than right- or left-handed children, according to a ... . The researchers behind the study, from ... their findings may help teachers and health professionals to ...
... ... the Christian perspective, promote faith-formation. , ... (PRWEB) January 24, 2010 -- Witness to Hope Ministries, a nonprofit ... behavioral health practice in Beaver, PA in order to serve at-risk and special needs ...
... 24, 2010 When University of Utah scientists discovered a ... conducting plastic or polymer, no one could explain how it ... later, the Utah researchers have found these "random lasers" occur ... say such lasers may prove useful for diagnosing cancer. ...
Cached Medicine News:Health News:Save The Ta-Ta's ... And Your Ticker 2Health News:Save The Ta-Ta's ... And Your Ticker 3Health News:Estn las Mujeres y los Nios de Hait Recibiendo Menos Ayuda Tras el Terremoto? 2Health News:Estn las Mujeres y los Nios de Hait Recibiendo Menos Ayuda Tras el Terremoto? 3Health News:Estn las Mujeres y los Nios de Hait Recibiendo Menos Ayuda Tras el Terremoto? 4Health News:Study confirms prostate cancer is treated differently at county vs. private hospitals 2Health News:Mixed-handed children more likely to have mental health, language and scholastic problems 2Health News:Mixed-handed children more likely to have mental health, language and scholastic problems 3Health News:Christian Nonprofit and Behavioral Health Practice Team Up to Help Children 2Health News:How 'random' lasers work 2Health News:How 'random' lasers work 3Health News:How 'random' lasers work 4Health News:How 'random' lasers work 5
... flexible continuous monitoring, the M3 and M4 ... and neonatal patient care. M Series monitors ... includes a basic set of non-invasive parameters ... Optional Multi-Measurement Server extensions offer Mainstream or ...
... On-line Electronic Help (OLEH), an ... to critical anesthesia-related information. OLEH brings ... need it most right on ... care of the patient and ...
Compact networked patient monitors for flexible care....
... for flexible care settings., ,IntelliVue ... portability and measurement flexibility to match ... intermediate care environmentsat the patients side., ... in patient monitoring, IntelliVue has highly ...
Medicine Products: