Navigation Links
Boehringer Ingelheim Enrolls First Patients in Pivotal Phase 3 Interferon-Free Hepatitis C Trial Program
Date:1/17/2013

d to announce that the first patients are now enrolled in our Phase 3 HCVerso™ program, including at U.S. trial sites," said Peter Piliero , M.D., Vice President, Clinical Development and Medical Affairs, Boehringer Ingelheim Pharmaceuticals, Inc. "Patients infected with HCV may benefit most from an individualized treatment approach since a person's genetics, type of virus, and stage of liver disease vary from patient to patient. Our investigational interferon-free regimen has shown particular promise in treating patients with HCV genotype-1b so we have decided to enroll these patients in our Phase 3 trial program. Our goal is for an interferon-free future and ensuring patients are treated with the most effective treatment for them individually."

Results from the SOUND-C2 study, which were presented in November 2012 at the 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD), found that up to 85 percent of patients infected with HCV GT-1b treated with Boehringer Ingelheim's investigational IFN-free regimen of faldaprevir, BI 207127 and ribavirin achieved viral cure at 12 and 24 weeks following treatment completion (SVR12 and SVR24).

Eliminating injectable interferon from treatment regimens is a critical goal in HCV as it can be difficult for patients to take due to long treatment duration and often severe side-effects. In addition, up to 50 percent of patients may not be eligible for treatment with interferon. Severe side-effects of interferon include heart failure, sepsis, leukopenia, depression and vision loss, resulting in adherence problems and treatment failure for many patients. Since 1999 there has been a significant increase in deaths due to chronic HCV, accounting for 15,000 deaths in the United States in 2007 alone.

"More effective and tolerable alternatives to interferon would help patients with their decision to start and
'/>"/>

SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Boehringer Ingelheim Presents New Phase II Data for Volasertib in Adult Patients with AML
2. Boehringer Ingelheim Announces Equine Research Awards
3. Phase 2b Data of Boehringer Ingelheims Interferon-Free Hepatitis C Treatment Show Viral Cure Achieved in Up to 85% of Treatment-Naive Patients
4. Whistleblowers extraordinary efforts helped win $95 million settlement with Boehringer Ingelheim
5. Boehringer Ingelheim announces afatinib expanded access program (EAP) for patients with EGFR mutation-positive advanced NSCLC
6. Boehringer Ingelheim and Lilly introduce the My Well Planner Lifestyle Improvement Program for Adults with Type 2 Diabetes
7. Lilly and Boehringer Ingelheim Present Data at the 72nd American Diabetes Association Scientific Sessions® from Phase II Studies Comparing Investigational Novel Basal Insulin to Insulin Glargine
8. Boehringer Ingelheim Presents First Data for Tiotropium in Adolescents with Moderate Persistent Asthma
9. Results of Phase II Study of Boehringer Ingelheims Investigational Bronchodilator for COPD Presented at 2012 ATS International Conference
10. Boehringer Ingelheim to present pivotal Phase III results for afatinib in first-line treatment of EGFR mutation-positive NSCLC at ASCO 2012
11. New Data to be Presented at the Annual American Thoracic Society International Conference Demonstrates Depth of Boehringer Ingelheim Respiratory Research Pipeline
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/10/2014)...  The U.S. Department of Health and Human Services ... (UH) Case Medical Center Seidman Cancer Center totaling $4.7 ... improving care for patients with complex cancer. ... a unique model developed at UH to enhance care ... or demonstrated need for high health care utilization.  ...
(Date:7/10/2014)... Yesterday, former Congressman Patrick Kennedy ... facility. Rep. Kennedy and Dick Moberg ... research in neurological disease and treatment. ... Garen Staglin , created One Mind, a ... that will radically accelerate the development and implementation ...
(Date:7/10/2014)... 2014  Decision Resources Group finds that while ... specialists are willing to prescribe Durata,s Dalvance (dalbavancin) ... as OPAT, approximately two-thirds of the respondents reported ... hospital inpatients. However, our findings indicate that nearly ... on OPAT following hospital discharge, and most are ...
Breaking Medicine Technology:University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4Representative Patrick Kennedy visits Moberg's medical device facility to discuss improvement in brain injury care 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 2Long-Acting Antibiotics Offering Once-Weekly Dosing Will See Favorable Uptake and Use as Outpatient Parenteral Antimicrobial Therapy (OPAT) 3
... (LSE: SHP, NASDAQ: SHPGY ), the global ... agreement with the Center for Drug Evaluation and Research ... to conduct additional clinical trials to confirm the clinical ... 1996 under Subpart H (an accelerated approval process) for ...
...   Remedi SeniorCare , one of the nation,s ... executive Corey Gauff as its new senior vice ... In his new position, Gauff will be responsible ... driving growth via Remedi,s innovative offerings, including the ...
Cached Medicine Technology:ProAmatine® (midodrine HCl) Update: Path Forward Agreed 2ProAmatine® (midodrine HCl) Update: Path Forward Agreed 3ProAmatine® (midodrine HCl) Update: Path Forward Agreed 4Remedi SeniorCare® Appoints Corey Gauff SVP of Sales and Account Management 2
(Date:7/12/2014)... Wright & Schulte LLC has filed a ... subsidiary of Johnson & Johnson, on behalf of an Ohio ... a metal-on-metal DePuy Pinnacle hip replacement and had to undergo ... implant. The DePuy hip lawsuit was filed July 7, 2014, ... No. 3:14-cv-2427) where DePuy Pinnacle Hip lawsuit litigation is ...
(Date:7/12/2014)... Warminster, PA (PRWEB) July 12, 2014 ... Paddock covering a variety of men’s health questions. ... issues specific to men, why women live longer than ... article, Men's Health Made Simple featured on ... can get a hernia at any age. If you ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 Utah Valley ... of startups, with awards being bestowed to companies in ... Utah’s outstanding entrepreneur community with recognition for new ideas ... model with incoming revenue. , 25 Under 5 highlights ... state that are under 5 years old. Award recipients ...
(Date:7/12/2014)... (PRWEB) July 12, 2014 A recent article ... provides a trio of suggestions for those seeking cosmetic ... days are rapidly approaching and the heat begins to enliven ... to their summer clothing, realizing that they didn’t work out ... , This can cause a sudden surge of people eager ...
(Date:7/12/2014)... 2014 Wright & Schulte LLC, an experienced ... For Men Lawsuits (case #59776/2014), announces they have launched ... that allege the popular hair dye, Just For Men, has ... face, neck and other areas. In addition to detailing symptoms ... burns , the advertisements being run by Wright & Schulte ...
Breaking Medicine News(10 mins):Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 2Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 3Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 4Health News:DePuy Pinnacle Hip Lawsuit Filed By Wright & Schulte LLC On Behalf of Ohio Man Who Required Revision Surgery Purportedly From Defective Hip Implant 5Health News:Ivyland Medical Center’s Dr. Brad Paddock Offers Tips for Men’s Health 2Health News:SquareHook is Recognized for UVEF 25 Businesses Under 5 Years-Watch Out 2Health News:Best Summer Cosmetic Surgeries Revealed in Article By Seattle Plastic Surgeon 2Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 2Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 3Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 4
... it or lose it, principle at work, one expert says ... may cut down on a man,s chances of developing erectile ... any other part of the body. It,s what we in ... it, concept," said Dr. Hossein Sadeghi-Nejad, an associate professor of ...
... Senator Specter to Reconsider and Support Bill that,Stops Cuts ... July 3 Gridlock has,paralyzed the U.S. Senate, derailing ... percent cut to doctors who treat Medicare patients, kept,Medicare ... that,44 million Americans depend on., Last week, Senator ...
... National and regional healthcare,leaders will convene in Mendocino County ... Patient Care in 2008.", "Ultimately we want to ... medical record software and by enabling the exchange,of clinical ... of Redwood MedNet, the conference host., The conference ...
... be inducted into the 2008 American Orthopaedic Society for Sports Medicine ... Meeting in Orlando. , ... Orlando, Florida (PRWEB) July ... be inducted into the 2008 American Orthopaedic Society for Sports ...
... representing doctors and beneficiaries criticize Senators,Hutchison and Cornyn ... and,improve Medicare, AUSTIN, Texas, July 3 ... Association to urge Senators Kay Bailey,Hutchison and John ... that,would stop a 10.6 percent cut to doctors ...
... older drugs as good as newer ones, study ... -- Taking prescription medications can help reduce violent ... , It included 1,445 schizophrenia patients randomly selected ... perphenanize, quetiapine, risperidone or ziprasidone. , Patient violence ...
Cached Medicine News:Health News:Lots of Sex May Prevent Erectile Dysfunction 2Health News:Pennsylvania Medical Society and AARP Criticize Senator Specter for Blocking Bill to Protect Access to Doctors and Improve Medicare 2Health News:Improving Healthcare in Rural Northern California Goal of One-Day Conference of National and State Healthcare Leaders 2Health News:Paolo Aglietti, MD, President of the International Society of Knee Surgery and Arthroscopy, Inducted into Sports Medicine Hall of Fame 2Health News:AARP, Texas Medical Association Join Forces to Urge Passage of Bill Protecting Access to Doctors and Improving Medicare 2Health News:AARP, Texas Medical Association Join Forces to Urge Passage of Bill Protecting Access to Doctors and Improving Medicare 3Health News:Medication Reduces Violence in Some Schizophrenics 2
... laboratories to work more efficiently has ... for innovative solutions. With the COBAS ... on-board measurement technologies, robotic handling of ... This supports the very broad menu ...
... Compact Size , The ADVIA 1200 system features ... in any size laboratory. , , Standardization as ... 1200 system uses the same reagents, calibrators and controls ... and is based on the same proven reliability. , ...
... Stryker Mainstay® ZIP Anchor is a family ... different sizes and suture options. The ZIP ... and 4.5mm size with either one strand ... #5 suture. Needles are attached to each ...
... Stryker BioZip Suture Anchor is a unique double ... BioZip is made from Poly-L Lactic Acid (PLLA) ... Needles are attached to the suture ends for ... arthroscopic repairs. The trocar tip inserter allows insertion ...
Medicine Products: