Navigation Links
Blueberry-Supplemented Diet Shows Promise in Lowering Cholesterol in Animal Trials
Date:6/19/2008

PORTLAND, Maine, June 19 /PRNewswire/ -- New research published in the British Journal of Nutrition (Br J Nutr., Dec. 17, PMID: 18081945, 2007) shows that blueberries may have a cardio-protective effect, by significantly lowering cholesterol. Lead scientist, Wilhelmina Kalt, Ph.D, from Agriculture and Agri-Food Canada conducted tests on pigs fed a blueberry-supplemented diet. Blueberry-supplemented diets resulted in a reduction in total cholesterol including both LDL and HDL levels. The greatest reduction in total, LDL and HDL cholesterol levels was found in pigs fed a 2% blueberry diet equivalent to approximately 2 one-cup servings of blueberries in the human diet. According to the study, this could be "...reasonably achieved in the adult human diet and suggests that the observed effect from blueberry supplementation could occur in healthy humans."

"In feeding trials, we found that blueberry supplementation reduced plasma cholesterol levels more effectively when the animals received a mostly plant-based diet than when they received a less heart-healthy diet," said Dr. Kalt. "The soy, oats and barley contained in these diets may have functioned synergistically with the blueberries to beneficially affect plasma lipids."

According to Kalt, pigs were selected for study because they have levels of LDL similar to humans and are susceptible to diet-induced vascular disease. Pigs can also develop atherosclerotic plaques in the aorta and carotid artery, and have a similar blood pressure and heart rate as humans.

The Antioxidant Power of Blueberries

The antioxidant activity of blueberries may help to explain their potential cardio-protective effect observed in this study. Antioxidants are free-radical quenchers, helping protect us against cellular oxidative damage that can lead to heart disease, degenerating brain function such as in Alzheimer's disease and some types of cancer. In a comprehensive study of the antioxidant capacity of foods, using a test tube assay called ORAC (Oxygen Radical Absorbing Capacity), blueberries ranked among the highest on the list. (Wu, X. et al. J Agric Food Chem 2004, 52:4026-37.) The major contributors to this high level of antioxidant activity are a family of compounds in blueberries called polyphenols -- particularly the flavonoids. (Prior, R.L. et al J Agric Food Chem. 1998, 46: 2686-93). "Flavonoids may act as antioxidants to inhibit LDL oxidation and thereby protect against vascular insult by oxidation," says Kalt. "Flavonoids may also reduce vascular inflammation related to atherosclerosis."

Dr. Kalt advises consumers to choose blueberries along with other brightly colored fruits and vegetables containing health-promoting antioxidants. The USDA recommends between 1 to 2 1/2 cups of fruit per day depending on age, gender and activity level. According to the USDA, just 1/2 cup of fruit delivers one fruit serving. "Eating more fruits and vegetables will help with weight control, disease prevention and promote healthy aging," said Kalt. "Get your blues every day by eating at least 1/2 cup of blueberries as part of a well-balanced diet."


'/>"/>
SOURCE The Wild Blueberry Association of North America
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Randomized Controlled Clinical Trial Shows Derma Sciences MEDIHONEY(TM) Eradicates MRSA From Chronic Venous Ulcers
2. New Study Shows BENICAR(R) (olmesartan medoxomil) Reverses Blood Vessel Damage Independent of Blood Pressure Lowering
3. Bionovos Drug Candidate for Menopausal Symptoms Shows Effect on Neural Pathways Related to Temperature Regulation
4. Inspires Phase 3 CF Trial, Using PARIs Nebulizer & Compressor, Shows Positive Top-Line Results
5. Video: Clinical Study Shows Liraglutide Reduced Blood Sugar, Weight, and Blood Pressure in Patients with Type 2 Diabetes
6. Pharmacyclics Novel Btk Inhibitor Shows Efficacy in Preclinical Models of Rheumatoid Arthritis and Lymphoma
7. Abbotts Phase III Sub-Group Analysis Shows Investigational TriLipix(TM) in Combination with CRESTOR(R) Improves Key Lipids in Patients with Mixed Dyslipidemia and Type 2 Diabetes
8. Study Shows Lantus(R) Helped People Living with Type 2 Diabetes Reach the ADAs Recommended Target for Blood Sugar Control
9. The Largest Ever Study of Diabetes Shows Intensive Glucose Control Reduces Serious Complications
10. Heart Patients More Likely to Adopt Healthy Habits in 3-Year Program Led by Cardiac Rehabilitation Experts, Mayo Clinic Research Shows
11. CellCept(R) and a Reduced Level of CNI Shows Trend Towards Preservation of Kidney Function Versus a Standard-Dose CNI
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... 24, 2016  Arkis BioSciences, a leading innovator ... more durable cerebrospinal fluid treatments, today announced it ... funding is led by Innova Memphis, followed by ... private investors.  Arkis, new financing will accelerate the ... market release of its in-licensed Endexo® technology. ...
(Date:6/23/2016)... 23, 2016  In a startling report released today, National ... by lacking a comprehensive, proven plan to eliminate prescription opioid overdoses. ... of how states are tackling the worst drug crisis in recorded ... – Kentucky , New Mexico ... . Of the 28 failing states, three – Michigan ...
(Date:6/23/2016)... Bracket , a leading clinical trial technology ... outcomes platform, Bracket eCOA (SM) 6.0, at the 52 ... 30, 2016 in Philadelphia , Pennsylvania.  A ... product of its kind to fully integrate with RTSM, will ... 6.0 is a flexible platform for electronic clinical outcomes assessments ...
Breaking Medicine Technology:
(Date:6/27/2016)... ... June 27, 2016 , ... A revolution is underway. ... transport experience for the millions of people who require these medical transport services ... industry through the use of technology. Now, SmartEMS has put forth an industry-changing ...
(Date:6/26/2016)... ... 2016 , ... Pixel Film Studios Released ProSlice Levels, a Media Slicing Effect ... videos a whole new perspective by using the title layers in ProSlice Levels ... , ProSlice Levels contains over 30 Different presets to choose from. FCPX ...
(Date:6/25/2016)... ... June 25, 2016 , ... ... and applications at AcademyHealth’s Annual Research Meeting June 26-28, 2016, at the Hynes ... important health care topics including advance care planning, healthcare costs and patient and ...
(Date:6/25/2016)... ... June 25, 2016 , ... First Choice Emergency Room , ... Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell Farm facility. , ... our new Mesquite location,” said Dr. James M. Muzzarelli, Executive Medical Director of First ...
(Date:6/25/2016)... ... ... Conventional wisdom preaches the benefits of moderation, whether it’s a matter of indulgence ... high can result in disappointment, perhaps even self-loathing. However, those who set the bar ... from PsychTests.com reveals that behind the tendency to set low expectations is ...
Breaking Medicine News(10 mins):