Navigation Links
Biotica Strikes Significant Collaboration Deal With GlaxoSmithKline
Date:1/12/2009

CAMBRIDGE, England, January 12 /PRNewswire/ -- Biotica Technology Limited, a privately-held biotechnology company, announces a significant Collaboration and License Agreement with GlaxoSmithKline to discover, develop and commercialise novel erythromycin-based macrolides in inflammatory diseases.

In a three year research collaboration, Biotica will use its bioengineering technology to produce compounds that are not readily accessible via conventional medicinal chemistry approaches. GSK will apply its expertise in macrolide drug discovery to optimize further the properties of candidate drugs, and will have responsibility for development and commercialisation.

Under the terms of the agreement, Biotica receives an initial cash payment, and is eligible to receive up to GBP86 million per compound in success-based development, approval and commercialisation milestone payments, as well as tiered royalties on net sales of resulting products. In addition, GSK has made an up front equity investment in a first close of Biotica's Series D financing. The Series D round remains open for additional investors and will support progression of the company's high-value, unpartnered programs.

"The deal with GSK significantly boosts our cash position and enables us to further strengthen our position as the leading natural product optimization company. We look forward to working with GSK to exploit the significant potential of macrolides in inflammatory diseases," said Dr. Edward Hodgkin, CEO of Biotica.

"Biotica's technology and expertise enables discovery of new medicines which could not be made by conventional means" said Dr. Ming Zhang, Biotica's Senior Vice President of R&D. "We had demonstrated our capacity for optimizing macrolides in a successful pilot study conducted prior to completion of the agreement" he added.

About Biotica

Biotica is a privately-held biotechnology company with a growing pipeline of novel therapeutic programmes supported by clinical validation. Biotica's programmes include rapamycin-based mTOR inhibitors (partnered with Wyeth), novel FK506 analogues for inhaled use in asthma, cyclophilin inhibitors and erythromycin macrolides (in collaboration with GlaxoSmithKline). All of Biotica's projects employ its proprietary technology, polyketide bioengineering, which enables it to select from the many known polyketides with biological activity and make a range of derivatives that are either difficult or impossible to make by medicinal chemistry methods. For additional information visit http://www.biotica.com

    Enquiries

    Biotica Technology Ltd       Tel: +44-1799-532920
    Dr Edward E. Hodgkin, CEO
    enquiries@biotica.com

    Financial Dynamics           Tel: +44(0)20-7831-3113
    Ben Atwell
    Ben.Atwell@fd.com



'/>"/>
SOURCE Biotica Technology Ltd
Copyright©2009 PR Newswire.
All rights reserved

Related medicine technology :

1. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
2. DEFLUX(R) Significantly Reduces Urinary Tract Infections in Children With Vesicoureteral Reflux
3. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
4. Vidaza Significantly Extends Overall Survival by 74% in Phase 3 Trial in Myelodysplastic Syndromes (MDS)
5. Nexavar Significantly Improved Overall Survival in Phase 3 Asia-Pacific Liver Cancer Trial
6. Largest Study to Date Shows Significant Reductions in Risks of Blood Clots and Reintervention With CYPHER(R) Sirolimus-eluting Coronary Stent Compared to Taxus Stent
7. Phase III Clinical Trial in Newly Diagnosed Multiple Myeloma Stopped Early Due to Highly Significant Efficacy Advantage of VELCADE(R) (Bortezomib) for Injection Based Therapy Across All Endpoints
8. Study Shows Vasopressin Receptor Antagonist VAPRISOL(R) (Conivaptan Hydrochloride Injection) Significantly Increased Serum Sodium Concentration in Patients with Euvolemic & Hypervolemic Hyponatremia
9. DOV 21,947 Demonstrates Significant Body Weight and BMI Reductions in Drug- Compliant Subjects in Phase Ib Clinical Study
10. FASgen Announces Significant Milestone in Its Cancer Drug Development Program
11. New Data Reveal Topical Divigel(R) (estradiol gel) 0.1% Significantly Reduces Frequency and Severity of Hot Flashes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/23/2016)... NEW YORK , May 23, 2016 /PRNewswire/ ... Mass Spectrometry Market Size, Share, Development, Growth and ... Platform (Hybrid, Single and Other), by Application (Drug ... Others), by End Users (Pharmaceuticals, Life Science and ... Published by P&S Market Research, the global ...
(Date:5/23/2016)... The World Health Organization (WHO) expanded the Intended Use of ... 13 years, and above. Effective immediately, the PrePex device, manufactured ... males in the 14 priority countries in Southern and ... circumcision device to receive WHO Prequalification on 31 May 2013. ... " The expanded use of PrePex for younger ...
(Date:5/23/2016)... 2016 Experts from various countries ... and the role of technology in innovative healthcare ... The First International Conference of VPS-Penn Medicine opened in ... presence of Sheikh Nahyan bin Mubarak Al Nahyan, Minister of ... which helps provide personalized medicine and tailor-made healthcare in disease ...
Breaking Medicine Technology:
(Date:5/25/2016)... Texas (PRWEB) , ... May 25, 2016 , ... The ... Myers Veterans Biomedical Technology Program to help provide veterans a pathway to employment and ... Executive, presented a $20,000 check to Nick Hallack, President and CEO of Medisend, parent ...
(Date:5/25/2016)... , ... May 25, 2016 , ... ... International University (FIU) Herbert Wertheim College of Medicine announced the AUA-FIU Global MD ... Degree and Global Health Certificate from AUA and a Certificate of Completion from ...
(Date:5/25/2016)... O'Fallon, MO (PRWEB) , ... May 25, 2016 , ... ... located in Woodlawn Plaza at 8618 Mexico Road, O’Fallon, MO 63366. He serves patients ... and cosmetic treatments . Dr. Schwarz’s success is reflected in the superior ...
(Date:5/25/2016)... ... May 25, 2016 , ... Today Omega Institute, a leading destination ... innovative workshops and training opportunities in the growing field of yoga therapy ... who are dealing with specific health issues—including injuries, illnesses, and temporary or chronic health ...
(Date:5/25/2016)... ... ... Cheryl Bowker of Bowker Insurance Group has been presented with one of ... McKenna ran one of Allstate’s most successful agencies for 48 years, but it was ... The award named for him is not given every year, but only when an ...
Breaking Medicine News(10 mins):