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Biopure Announces 2007 Third Quarter Financial Results
Date:8/23/2007

tion during times of coronary artery blockage.

A revised protocol for the company's HEM-0125 50-patient Phase 2 trauma trial in South Africa has been approved by the University of the Witwatersrand Human Research Ethics Committee. The company made the revisions in an attempt to make enrollment simpler. The revised protocol may be implemented following receipt of regulatory approval from the South Africa Medicines Control Council. This study is designed to assess the safety and tolerability of Hemopure, compared to standard therapy, for the emergency treatment of unstable trauma patients in hospital. The company hopes to see acceleration in the rate of patient enrollment with the revised protocol.

Possible Transaction

As an update to the CEO July 2007 letter to stockholders, the company recently announced certain terms that have been discussed with Malaysian governmental entities and individuals on a nonbinding basis for a possible license joint venture arrangement in Malaysia. Such a transaction might occur if and after the company receives market authorization for Hemopure in the U.K. Matters discussed were possible (a) investment in Biopure common stock, but not more than 20%, and (b) financing for a large-scale manufacturing facility. Many terms were not addressed and would have to be considered if a transaction were to occur.

Biopure Corporation

Biopure Corporation develops, manufactures and markets pharmaceuticals, called oxygen therapeutics, that are intravenously administered to deliver oxygen to the body's tissues. Hemopure(R) [hemoglobin glutamer -- 250 (bovine)], or HBOC-201, is approved for sale in South Africa for the treatment of surgical patients who are acutely anemic. Biopure has applied in the United Kingdom for regulatory approval of a proposed orthopedic surgical anemia indication. The company is developing Hemopure for a potential indication in cardiovascular ischemia, in addition to supporting the U.S. Navy's govern
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SOURCE Biopure Corporation
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