Navigation Links
Bionovo Discovers New Estrogen Regulatory Elements for Breast Cancer and Osteoporosis Drugs
Date:6/16/2008

- Results Presented at Endocrine Society's 90th Annual Meeting -

SAN FRANCISCO and EMERYVILLE, Calif., June 16 /PRNewswire-FirstCall/ -- Bionovo Inc. (Nasdaq: BNVI) today announced results on the role of estrogen regulatory elements important in developing drugs for breast cancer and osteoporosis. The data, which were presented at the Endocrine Society's 90th Annual Meeting, showed that the new regulatory elements are essential for the differentiation of the estrogenic pharmacological activity exerted by different compounds.

"Selective estrogen receptor modulators (SERMs) differ from estrogen in how they regulate gene transcription and result in different pharmacological profiles and clinical effects," said Dr. Dale Leitman, from the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco. "This study identified gene elements that are activated by SERMs but not by estrogens used in hormone therapy. The identification of these elements, coupled with the understanding of the differential regulation in various tissues, provides a new platform for the discovery of estrogenic drugs with SERM-like profiles."

The study was conducted by investigators at The Center for Reproductive Sciences in the Department of Obstetrics, Gynecology and Reproductive Sciences at the University of California, San Francisco in collaboration with scientists at Bionovo.

"The discovery of these selective estrogen regulatory elements strengthens our SERM discovery engine," said Isaac Cohen, Bionovo's chairman and chief executive officer. "The advantage of the new array of specific regulatory elements is manifest in the pharmacological and toxicological insights gained. We can now acquire
'/>"/>

SOURCE Bionovo Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Bionovo Announces Publication of the Paper Detailing the Mechanism of Action of Its Cancer Drug BZL101
2. Bionovo Announces Positive Developments in On-going Phase 1/2 Cancer Drug Trial
3. deCODE Discovers Novel Genetic Links Between Pigmentation Traits and Risk of Skin Cancer
4. Dynamis Therapeutics, Inc. Discovers RAGE Inhibitor
5. St. Jude Discovers Factors That Accelerate Resistance to Gleevec(TM) Targeted Therapy in Lymphoblastic Leukemia
6. Video: New Research Discovers Independent Brain Networks Control Human Walking
7. National Stem Cell Holding, Inc. Discovers Non-Embryonic Biomaterials that Promote Tissue Repair
8. Wyeth Presents New Phase 3 Data and Updates Regulatory Timing for NDA Filing of Bazedoxifene/Conjugated Estrogens
9. XTENT Announces European Regulatory Update
10. Morria Biopharmaceuticals Plc Announces Regulatory Approval to Commence Phase II Clinical Study of MRX-4 in Allergic Rhinitis
11. PulmoBioTech Announces Details of Its Regulatory Approval Experiments
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)... 2015  The Partnership to Fight Chronic Disease (PFCD) released a public ... and a new study analyzing the impact of increased cost sharing ... coalition working to educate policy makers and the public on the ... focused on how the Iowa healthcare exchange ...
(Date:1/23/2015)... and DUBLIN , Jan. 23, 2015 ... with KRS Global Biotechnology, Inc. for the compounding, packaging and ... for shipment in the United States . ... Outsourcing Facility capable of compounding naltrexone tablets in various strengths ...
(Date:1/23/2015)... 23, 2015  iMD Companies, Inc. (ICBU) has repositioned itself as ... and grab a foothold in the hydroponic, hemp and medical ... a presence in the sector, and recently partnering with the ... hemp and medical marijuana, iMD is committing to bring its ...
Breaking Medicine Technology:New research shows Iowa health exchange would benefit from improvements 2New research shows Iowa health exchange would benefit from improvements 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 2Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 3Immune Therapeutics, Inc. Announces Agreement with KRS Global Biotechnology, Inc. 4iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2
... ORLEANS, June 16 Cardinal Health, a,global provider ... and,productivity of health care, today announced that it ... (PET),radiopharmaceuticals for clinical trials., The company,s new ... at the Society of Nuclear Medicine,s (SNM) 55th ...
... the efficacy of RESPeRATE while highlighting ... BERLIN and NEW YORK, June 16 European Society ... Ltd., a medical device,company publicly traded on the Tel-Aviv ... studies and analysis highlighting RESPeRATE,-- the only medical device ...
Cached Medicine Technology:Cardinal Health Expands PET Nuclear Pharmacy Services to Support Clinical Drug Trials 2Blood Pressure Lowering Effect of Hypertension Treatment Device Further Validated in New Studies 2Blood Pressure Lowering Effect of Hypertension Treatment Device Further Validated in New Studies 3Blood Pressure Lowering Effect of Hypertension Treatment Device Further Validated in New Studies 4
(Date:1/22/2015)... York (PRWEB) January 22, 2015 The federal ... in the U.S. District Court, Southern District of West Virginia ... Inc. in that proceeding’s first bellwether trial. In an Order ... a new trial after finding that C.R. Bard had not ...
(Date:1/22/2015)... has released a new blog post explaining the main features ... , Auto insurance quotes help many drivers find the best ... call an agent or visit an agency for price information. ... http://autocarinsurancebest.com/ . , Every business who relies heavily on ...
(Date:1/22/2015)... NY (PRWEB) January 22, 2015 ... of Sports Medicine flagship journal Medicine & Science ... L-Citrulline before exercise may help reduce gastrointestinal (GI) ... 1 , Participants in the double-blind, placebo-controlled ...
(Date:1/22/2015)... (PRWEB) January 22, 2015 Four years since the ... – which coincided with the marriage of Avasa & Matthew Love ... ROAD, which is scheduled for release through White Swan Records on ... that there is a sacred path available to all of us ...
(Date:1/22/2015)... JJsHouse.com is a famous dress online store ... announces its latest collection of wedding dresses , and ... issue is the wedding dress on your big day; the ... life. Every bride wants to find the most suitable wedding ...
Breaking Medicine News(10 mins):Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 2Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 3Health News:Court Upholds $2 Million Vaginal Mesh Lawsuit Verdict Levied Against C.R. Bard in First Federal Bellwether Trial, Bernstein Liebhard LLP Reports 4Health News:Commercial Auto Insurance Provides Several Important Features! 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 2Health News:Study Shows Kyowa Hakko’s L-Citrulline May Help Reduce Gastrointestinal Injury During Strenuous Exercise 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4Health News:Find The Most Suitable Wedding Dress At JJsHouse.com 2
... Industries Ltd. (Reuters: SUN.BO, Bloomberg: SUNP IN, NSE: SUN ... Company Exclusive Group Ltd. (Alkaloida), has extended the Expiration ... all outstanding Ordinary Shares of Taro Pharmaceutical Industries Ltd. ... p.m., New York City time, on Friday, April 3, ...
... cognitive disorders, researchers say , , FRIDAY, March 20 ... "the edge of chaos," at a critical point ... who said their finding could help improve understanding ... The researchers used medical imaging to measure changes ...
... some groups, survival odds after angioplasty are not as ... major international study pinpoints which people with major heart ... than artery-opening angioplasty. , "Bypass surgery is preferable for ... Hlatky, professor of health research and policy and cardiovascular ...
... - Mayo Clinic research shows a correlation between inadequate ... taken by patients who have chronic pain. This correlation ... to treat chronic pain. According to the Centers for ... cause of disability in the United States. These patients ...
... Lead to a New Definition of ,Bedside Manner,WASHINGTON and ... Health Resource Center (NWHRC) just released the latest issue ... "Women & Health Care Reform." The report coincides ... effort to gain support and awareness of the need ...
... N.C., March 20 The Government of Kenya ... 870 health workers contracted over the past three ... the country,s severe shortage of health professionals.Designed to ... public health facilities using a private-sector outsourcing mechanism, ...
Cached Medicine News:Health News:Sun Pharmaceutical Extends Tender Offer for Taro 2Health News:Sun Pharmaceutical Extends Tender Offer for Taro 3Health News:Diabetics and Elderly May Fare Better With Bypass 2Health News:Diabetics and Elderly May Fare Better With Bypass 3Health News:Mayo Clinic Study Suggests Those Who Have Chronic Pain May Need to Assess Vitamin D Status 2Health News:Mayo Clinic Study Suggests Those Who Have Chronic Pain May Need to Assess Vitamin D Status 3Health News:National Women's Health Report Addresses Issues of Uninsured Plus New Paradigms of Care 2Health News:Kenya Government Appoints Emergency Health Workers to Permanent Positions 2Health News:Kenya Government Appoints Emergency Health Workers to Permanent Positions 3
... Freedom leg bags are part ... a versatile line of leg bags, ... the varied needs of our customers. ... several sizes, and constructed of 100% ...
... are part of the Freedom Urinary ... leg bags, kits, and accessories designed ... our customers. These leg bags are ... of 100% latex-free soft, textured medical ...
... line of Personal Catheters® ... you would choose for ... configurations - standard, antibacterial, ... - are based on ...
The Antibacterial Personal Catheter® features a unique silicone composition that provides an antibacterial coated soft outer layer of silicone combined with a firm inner layer....
Medicine Products: