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Bionovo Announces Second Quarter 2009 Highlights and Financial Results
Date:8/10/2009

radiol, some differences existed in both the classes of genes regulated and the magnitude of regulation. These results demonstrate that ERb-selective agonists do not entirely mimic the actions of estradiol after binding to ERb, suggesting that the two classes of drugs will have different biological effects and different side effect profiles. Additionally, this study found that different types of ERb-selective drugs regulated different genes to varying extents and that therefore different ERb-selective drugs should exert distinct clinical effects. Of the different compounds investigated, Menerba (MF101) was one of the most ERb-selective, and patterns of gene expression were most disparate between Menerba and estradiol. Menerba also demonstrated unique cell type-specific gene regulation. -- The Company continues to work towards satisfying the FDA's requests for clarification of the manufacturing and analytical strategy to be used in ensuring the consistency of its drug products. -- The Company is aggressively pursuing a variety of funding options which include government grants, partnering, and debt and equity offerings. -- The Company has selected two more potential contract manufacturing organizations (CMO) to handle clinical, and possibly, commercial needs, and expects to qualify the primary CMO for clinical production by the end of September.

Second Quarter Results

Total operating expenses for the three months ending June 30, 2009 were $4.1 million compared to $4.4 million for the same period in 2008 and $4.6 million for the first quarter of 2009. Total operating expenses for the second quarter included purchases of lab supplies and raw materials to support the manufacturing process development efforts of its lead drug candidate,
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SOURCE Bionovo, Inc.
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Related medicine technology :

1. Bionovo Announces Positive Developments in On-going Phase 1/2 Cancer Drug Trial
2. Bionovo Announces Publication of the Paper Detailing the Mechanism of Action of Its Cancer Drug BZL101
3. Bionovo Discovers New Estrogen Regulatory Elements for Breast Cancer and Osteoporosis Drugs
4. Bionovos Drug Candidate for Menopausal Symptoms Shows Effect on Neural Pathways Related to Temperature Regulation
5. Bionovo Elucidates Mechanism of Breast Cancer Control by Estrogen Receptor Beta
6. Bionovo Reports on Metabolic Studies Related to Its Menopausal Hot Flash Drug Candidate
7. Bionovos MF101 Shows Statistically Significant Improvement in Sleep Disturbance from Hot Flashes
8. Bionovos VG101 Shows Greater Efficacy Than Estrogen in the Treatment of Vaginal Dryness
9. Bionovo Advances BZL101 to Phase 2 Clinical Trials After Positive Phase 1 Results for Metastatic Breast Cancer
10. Bionovo Presents Positive Results from Phase 1B Trial of BZL101 for Metastatic Breast Cancer at the Society for Integrative Oncology
11. Bionovo Announces Development Plans for Menopausal Hot Flash Drug Candidate, Menerba (MF101), Following FDA Meetings
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