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Bionovo Announces Second Quarter 2009 Highlights and Financial Results
Date:8/10/2009

EMERYVILLE, Calif., Aug. 10 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI) today announced second quarter highlights and financial results for the three months ended June 30, 2009.

Company Highlights

    -- Further results from the phase 1B clinical trial of Bezielle (BZL101)
       in 27 patients with metastatic breast cancer showed Bezielle to be
       safe and well-tolerated with encouraging evidence of clinical activity
       in a heavily pretreated patient population - most importantly
       including:

       -- 31% had stable disease for more than 90 days;
       -- 13% had stable disease for more than 180 days;
       -- three patients had objective tumor regression;
       -- one patient had objective tumor regression while on Bezielle
          therapy for 449 days and continues to be stable off of study
          medication for over 600 days;
       -- a second patient continues to be stable for 832 days and has not
          started any new anticancer treatment;
       -- a third patient was stable without any new anticancer therapy for
          591 days;
       -- there were no deaths or serious adverse events that were attributed
          to Bezielle (BZL101); and
       -- the most common side effects associated with Bezielle (BZL101) were
          minor and gastrointestinal in nature.


       These results provide further evidence that Bezielle (BZL101) may
       provide an important option for women suffering from advanced breast
       cancer, an extremely difficult to treat subset of the breast cancer
       population.

    -- On the SERM platform, a peer-reviewed study published in the journal
       "Public Library of Science One" found that when comparing the gene
       expression induced by ERb compounds to that induced by est
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SOURCE  Bionovo, Inc.
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Related medicine technology :

1. Bionovo Announces Positive Developments in On-going Phase 1/2 Cancer Drug Trial
2. Bionovo Announces Publication of the Paper Detailing the Mechanism of Action of Its Cancer Drug BZL101
3. Bionovo Discovers New Estrogen Regulatory Elements for Breast Cancer and Osteoporosis Drugs
4. Bionovos Drug Candidate for Menopausal Symptoms Shows Effect on Neural Pathways Related to Temperature Regulation
5. Bionovo Elucidates Mechanism of Breast Cancer Control by Estrogen Receptor Beta
6. Bionovo Reports on Metabolic Studies Related to Its Menopausal Hot Flash Drug Candidate
7. Bionovos MF101 Shows Statistically Significant Improvement in Sleep Disturbance from Hot Flashes
8. Bionovos VG101 Shows Greater Efficacy Than Estrogen in the Treatment of Vaginal Dryness
9. Bionovo Advances BZL101 to Phase 2 Clinical Trials After Positive Phase 1 Results for Metastatic Breast Cancer
10. Bionovo Presents Positive Results from Phase 1B Trial of BZL101 for Metastatic Breast Cancer at the Society for Integrative Oncology
11. Bionovo Announces Development Plans for Menopausal Hot Flash Drug Candidate, Menerba (MF101), Following FDA Meetings
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