Date:3/15/2010

as a target for cancer therapies has been actively pursued by many pharmaceutical companies. To the Company's knowledge, this is the first report demonstrating effective inhibition of both mTOR complexes concomitantly through a novel mechanism. BN107 has a potentially unique way to target a specific sub-group of breast cancer cells that currently has no selective treatment.

Successful financing for $17.4 million of net proceeds in a fully marketed public offering.

Notable additions to our network of advisors and consultants, including leading healthcare professionals with extensive experience in the development of therapeutic treatments, including:

• Daniel Shames, M.D., former Director of the Division, Reproductive and Urologic Drug Products, U.S. Food and Drug Administration (FDA).
• David Lin, former Chemistry Reviewer for the Office of New Drug Products, including Division, Reproductive and Urologic Drug Products, U.S. Food and Drug Administration (FDA).

During 2009, Bionovo significantly strengthened its Scientific Advisory Board (SAB) and Medical Advisory Board (MAB) with the addition of several world-renowned scientists and clinicians, including: '/>"/>

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