Navigation Links
Bionovo Advances BZL101 to Phase 2 Clinical Trials After Positive Phase 1 Results for Metastatic Breast Cancer
Date:11/3/2008

EMERYVILLE, Calif., Nov. 3 /PRNewswire-FirstCall/ -- Bionovo, Inc. (Nasdaq: BNVI) announced today that its drug candidate for metastatic breast cancer, BZL101, will advance to Phase 2 clinical testing after the successful completion of a second Phase 1 clinical trial.

The Phase 1B clinical trial was conducted to identify the maximum tolerated dose of BZL101 and to determine the safety and feasibility of the company's novel, oral, anticancer treatment. A total of 27 women with metastatic breast cancer were enrolled to this Phase 1B trial. A total of 48 women with advanced breast cancer have been treated with BZL101 in all clinical trials to date. Results from the Phase 1B show Bionovo's lead drug candidate for advanced breast cancer continues to be safe and well-tolerated, with early signs of clinical efficacy. The company will present the findings from the Phase 1B in an oral presentation of the best scoring abstracts at the Society of Integrative Oncology's Fifth International Conference on November 20, 2008 in Atlanta, Georgia.

"We are encouraged by the results of the Company's second Phase 1 trial in women with advanced breast cancer," said Isaac Cohen, President and CEO, Bionovo. "There are currently over 160,000 women in the United States living with advanced breast cancer who are eagerly awaiting an oral anticancer drug with minimal side effects and the ability to extend life without profoundly diminishing quality of life. We believe BZL101 may be an important new anticancer agent because its biological selectivity allows the drug to kill cancer cells without affecting normal cells. This will lead to a dramatically lower side effect profile."

Phase 2 Clinical Trial

The Phase 2 clinical trial is currently
'/>"/>

SOURCE Bionovo, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Bionovos VG101 Shows Greater Efficacy Than Estrogen in the Treatment of Vaginal Dryness
2. Bionovos MF101 Shows Statistically Significant Improvement in Sleep Disturbance from Hot Flashes
3. Bionovo Reports on Metabolic Studies Related to Its Menopausal Hot Flash Drug Candidate
4. Bionovo Elucidates Mechanism of Breast Cancer Control by Estrogen Receptor Beta
5. Bionovos Drug Candidate for Menopausal Symptoms Shows Effect on Neural Pathways Related to Temperature Regulation
6. Bionovo Discovers New Estrogen Regulatory Elements for Breast Cancer and Osteoporosis Drugs
7. Bionovo Announces Publication of the Paper Detailing the Mechanism of Action of Its Cancer Drug BZL101
8. Bionovo Announces Positive Developments in On-going Phase 1/2 Cancer Drug Trial
9. MedImmune Advances Pediatric Disease Prevention Program With Start of Phase 1/2a Clinical Trial for Respiratory Syncytial Virus Vaccine
10. Anpath Group, Inc. Advances Relationship With the Washington Metropolitan Area Transit Authority (Metro)
11. Despite Advances in the Accuracy of CT Colonography in Detecting Polyps, Digestive Health Experts Urge Patients to Consider Risks and Realities
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... and Markets ( http://www.researchandmarkets.com/research/dl9gbg/admetoxicology ) has announced ... Strategic Business Report" report to their offering. ... Testing in US$ Million by the following Segments: Toxicology ... The report provides separate comprehensive analytics for the US, ... , Europe , Asia-Pacific ...
(Date:4/17/2015)... 17, 2015 Research and Markets ( ... "Mammography Equipment - Global Strategic Business Report" report ... worldwide markets for Mammography Equipment in US$ Thousands by ... Mammography Equipment. The report provides separate comprehensive analytics for ... Japan , Europe , ...
(Date:4/17/2015)... , April 17, 2015 Today, the ... 13 employees from 12 biopharmaceutical companies as "We ... in policy advocacy and community service. ... Champion Awards were created by the biopharmaceutical industry ... in their careers, but have also shown an ...
Breaking Medicine Technology:ADME-Toxicology Testing (In-Vivo, & In-Vitro) Market - Global Strategic Business Report 2015: Pharma Industry Renews Focus on Cost Optimization 2Mammography Equipment (Analog & Digital) Market 2015-2020 - Global Strategic Business Report: Breast Imaging Screening Programs Push Sales 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 2PhRMA Applauds 2015 We Work For Health Champion Award Winners 3
... As crazy as it sounds, recent studies,conducted ... suggest there,s a,connection between stubborn stress-related belly bulge, ... pill, Relacore(R) (from the,Carter-Reed Company) ... and that ... stress increases cortisol (the stress hormone) and cortisol ...
... Inc. (Nasdaq: IDEV ) announced today that ... Research Council (MRC) that after,review of data from ... the Company,s,candidate vaginal microbicide for HIV prevention, the ... low-dose arm (0.5%),continue to be tested for safety ...
Cached Medicine Technology:Recent Studies Suggest Popular 'Diet Pill' Relacore Reduces Acne Breakouts 2Indevus Pharmaceuticals Provides Update on PRO 2000 Program 2Indevus Pharmaceuticals Provides Update on PRO 2000 Program 3Indevus Pharmaceuticals Provides Update on PRO 2000 Program 4
(Date:4/17/2015)... York (PRWEB) April 17, 2015 ... allege this class of prescription medications increases the ... attack, stroke or other life-threatening cardiovascular event continue ... U.S. District Court, Northern District of Illinois. According ... U.S. Judicial Panel on Multidistrict Litigation (JPML) on ...
(Date:4/17/2015)... San Francisco, CA (PRWEB) April 17, 2015 The ... Open House event and Free Application Day on April 29. The ... the ACTCM Pioneer Square, located at 555 DeHaro St. in San ... , 11 a.m. – Check in at the DeHaro campus (room ... a.m. – Tour of campus, Noon – Light lunch with current ...
(Date:4/17/2015)... April 17, 2015 With Dr. Taj ... has spent the last four years providing residents ... procedures ranging from general cleanings to dental implants and ... opening at their new office in North Charlotte. , ... as their Concord office, including denture fittings, cosmetic procedures, ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 ... to polish and perfect facial skin with its ... seeds and blend of energizing botanicals. This cushiony ... cells that cause breakouts and inhibit penetration of ... , Ecuadorian Ivory Palm Seeds, This uncommon exfoliating ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 Verndale, a ... it has once again been chosen as a Boston ... growing private company in the region. The BBJ’s Pacesetters ... growth from 2011 through 2014. This is the eighth ... ten years that Verndale has been honored with this ...
Breaking Medicine News(10 mins):Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 2Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 3Health News:Testosterone Treatment Lawsuits Increase, as New Report Indicates Over 200 Federal Cases Filed Since March 4Health News:American College of Traditional Chinese Medicine Hosts Open House 2Health News:Mario Badescu Skin Care Launches Botanical Exfoliating Scrub 2Health News:Verndale Honored as 2015 Boston Business Journal Pacesetter, Named 46th Fastest Growing Private Company 2
... Va. Research reported in the October issue of ... a molecular imaging technique may prove useful in early ... "One of the most promising aspects of molecular ... long before changes in the tumor size and shape ...
... review article published in the October issue of ... Clinic physicians differentiate the ethical and legal permissibility ... comfort measures, specifically palliative sedation, from that of ... that palliative sedation has an important place on ...
... published study in the October 2010 issue of The ... conducted at New York University,s College of Dentistry, confirms ... for controlling xerostomia, or dry mouth. The double masked, ... unique mucoadhesive patch, affixed to the hard palate inside ...
... It Real," an evidence-based sex education curriculum developed by researchers ... (UTHealth), will be implemented in select public schools across the ... tackle the U.S. teenage pregnancy rate. The U.S. ... of its $155-million total package to a team led by ...
... sciences for the developing world, will hold its 21st General ... 350 scientists from 35 countries are expected to attend. Dr. ... delegates at the opening ceremony. The opening ceremony will ... Ernesto Illy Trieste Science Prize and the official presentation of ...
... is a major cause of vision problems in children and ... 70 in developed countries. In amblyopia the person,s stronger eye ... as a result. When the condition is detected and treated ... 20/30 vision or better, the Amblyopia Treatment Study reports. But ...
Cached Medicine News:Health News:Evaluation of targeted therapy in ovarian cancer 2Health News:New approach for treating dry mouth presented in study published in October 2010 issue of JADA 2Health News:New approach for treating dry mouth presented in study published in October 2010 issue of JADA 3Health News:UTHealth researchers awarded $15 million for teen pregnancy prevention 2Health News:TWAS to meet in India 2Health News:Is photoscreening the best way to catch 'lazy eye'? 2
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 8.0 mm and length 10 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 6.0 mm and length 10 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 8.0 mm and length 7.5 mm....
Extremely wide blade opening. Excellent bio and MRI compatibility. Lot number on each clip. Long reliable history. Large type 1/1 (mm), opening width 13.0 mm and length 12 mm....
Medicine Products: