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BioMarin Announces Third Quarter 2010 Financial Results
Date:10/28/2010

Previous 2010 GuidanceCost of Sales (% of Total Revenue)

Unchanged

19% to 20%Selling, General and Admin. Expense*

$147 to $152

$145 to $150Research and Development Expense*

$147 to $152

$140 to $145Amortization and Contingent Consideration

$8 to $9

NAInterest Income

$4

$3 to $4 GAAP Net Income (Loss)**

$213 to $218

$(6) to $2Stock Compensation Expense

Unchanged

$37Non-GAAP Net Income

$28 to $33

$30 to $38*  Previous guidance did not include $5.0 million to $7.0 million in additional operating expenses associated with the acquisition of ZyStor Therapeutics, Inc.**  Includes $223.1 million resulting from reversal of deferred tax asset valuation allowanceAnticipated Upcoming Milestones4Q 2010: File IND for BMN-673 (PARP inhibitor)December 2010/ January 2011: Initiation of Phase 1 trial for BMN-701 for Pompe diseaseEarly 2011: Initiation of pivotal Phase III trial for Firdapse for LEMS in the U.S.Early 1Q 2011: Initiation of pivotal Phase III trial for GALNS for MPS IVA1Q 2011: Initiation of Phase Ib trial for BMN-673 (PARP inhibitor)Mid-2011: Final top-line results from PEG-PAL Phase II trial, including daily dosing and formulation studiesLate 2011: Availability of blood Phe monitor4Q 2011/1Q 2012: Initiation of Phase III PEG-PAL trial1Q 2012: Initiation of Phase I trial for BMN-111 for Achondroplasia1H 2012: NDA filing for Firdapse for LEMS in the U.S.4Q 2012: Approval of Firdapse for LEMS in the U.S.4Q 2012: U.S. and European filings for GALNS for MPS IVAResearch and Development ProgramsBioMarin continues to make significant investments in research and development to ensure continued growth of the company.  The current pipeline includes programs which are in various stages of development and are focused on treating a range of unmet medical needs.Advanced Programs

  • Firdapse: BioMarin expects to initiate a Phase III trial f
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  • SOURCE BioMarin Pharmaceutical Inc.
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