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BioMarin Announces Fourth Quarter and Full Year 2010 Financial Results
Date:2/17/2011

l items (Adjusted EBITDA).  Beginning in 2011, the non-GAAP Adjusted EBITDA measure rather than the prior non-GAAP income will be utilized in discussing financial performance as this metric is more aligned with management's internal goal setting process.The following tables detail the reconciliation of non-GAAP to GAAP financial metrics:

Reconciliation of GAAP Net Income (Loss) to Non-GAAP Net Income For the Three and Twelve Months Ended December 31, 2010 and 2009(in millions)(unaudited) Three Months Ended
December 31,Years Ended
December 31,NOTES2010200920102009GAAP Net Income (Loss)$ (12.2)$   4.7$ 205.8$ (0.5)Stock-based compensation expense9.88.837.534.5Upfront license fees

(1)---8.8Impairment charges

(2)---5.9Net gain on the sale of equity investments--(0.9)(1.6)Debt conversion expense

(3)13.7-13.7-Acquisition expenses

(4)--1.8-Tax benefit

(5)--(223.1)-Non-GAAP Net Income$  11.3$ 13.5$   34.8$ 47.1(1)  Represents upfront license payments related to our collaboration agreement with La Jolla Pharmaceutical Company in the first quarter of 2009.   (2)  Includes impairment losses on investments in Summit plc. and La Jolla Pharmaceutical Company recognized during the first quarter of 2009.(3)   Represents debt conversion expense associated with the early conversion of a portion our convertible debt in November 2010.(4)   Represents transactions costs associated with the acquisition of ZyStor Therapeutics Inc., during the third quarter of 2010.   (5)  Represents only the portion of total tax expense for the period related to the reversal of the Company's income tax valuation allowance during the third quarter of 2010.Reconciliation of GAAP Net Income (Loss) to EBITDA and Adjusted EBITDAFor the Year Ended December 31, 2010 with Guidance for 2011(in millions)(unaudited) NOTESYear EndedDecember 31, 2010Year Ending
December 31, 2011GuidanceGA
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SOURCE BioMarin Pharmaceutical Inc.
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