Navigation Links
BioLineRx Reports Publication in Peer Review Journal of Positive Phase 1/2 Results in Stem Cell Mobilization for Multiple Myeloma
Date:11/19/2013

JERUSALEM, Nov. 19, 2013 /PRNewswire/ -- BioLineRx (NASDAQ: BLRX; TASE: BLRX), a biopharmaceutical development company, announced today the publication of results showing that BL-8040 (formerly known as BKT-140) enables the efficient mobilization of stem cells from the bone marrow into the peripheral blood, thus facilitating autologous stem cell transplantation in multiple myeloma patients. The research was published in the journal, Clinical Cancer Research.

(Logo:  http://photos.prnewswire.com/prnh/20130730/630769)

High-dose chemotherapy followed by autologous stem cell transplantation has emerged as an established treatment modality for a variety of hematologic malignancies, including multiple myeloma, non-Hodgkin lymphoma and Hodgkin lymphoma. Stem cells are mobilized from the bone marrow using granulocyte colony-stimulating factor (G-CSF), harvested from the peripheral blood by apheresis, and re-infused to the patient after chemotherapy. This type of treatment often replaces the more traditional use of bone marrow transplantation, because the stem cells are easier to collect and the treatment allows for a quicker recovery time and fewer complications.

In patients that do not respond well enough to G-CSF (up to 20% in multiple myeloma), treatment is often augmented by Plerixafor, a drug that inhibits CXCR4, a chemokine receptor that is important in hematopoietic stem cell homing to the bone marrow. However, even after the dual treatment, the mobilization of a sufficient number of stem cells remains a difficult objective in a sizeable proportion of patients.

BL-8040 is a novel, potent and selective inhibitor o
'/>"/>

SOURCE BioLineRx
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. BioLineRx Reports Third Quarter 2013 Financial Results
2. BioLineRx to Report Third Quarter 2013 Results on November 13, 2013
3. BioLineRx to Hold Analyst and Investor Day in New York on November 21, 2013
4. BioLineRx Receives Regulatory Approval to Commence Phase 1/2 Trial for Novel Treatment of Celiac Disease
5. BioLineRx Announces In-Licensing of BL-9020, for Treatment of Type 1 Diabetes
6. BioLineRx Announces Regulatory Submission for Phase 1/2 Trial for Novel Treatment of Celiac Disease
7. BioLineRx Announces Receipt of a Notice of Allowance from USPTO for Patent on Use of BL-8020, an Oral, Interferon-Free Treatment for Hepatitis C
8. BioLineRx To Present At 15th Annual Rodman & Renshaw Global Investment Conference In New York
9. BioLineRx Announces Issuance of United States Patent Covering Use of BL-8040 for Obtaining Stem Cells
10. BioLineRx to Present at 15th International Celiac Disease Symposium
11. BioLineRx to Present at 2013 Stifel Nicolaus Healthcare Conference In Boston
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... 2014  Diplomat, the nation,s largest independent specialty pharmacy, ... to the Board of Directors on September 15, 2014. ... serve as chair of the Audit Committee. ... financial, compliance and operating experience in the health care ... chief financial officer, chief operating officer and secretary of ...
(Date:9/19/2014)... Mass. , Sept. 19, 2014  Alere Inc. ... rapid diagnostics, issued the following statement today in support ... Antibiotic-Resistant Bacteria. "As the global leader in ... for establishing a national strategy to address the serious ... to work with the Administration on initiatives to promote ...
(Date:9/19/2014)... September 19, 2014 Aufgrund ... den äußerst erfolgreichen Serialisierungs-Countdown-Kalender aktualisiert, der jetzt auch ... PDF, verfügbar unter pharmaserialisation.com , zeigt die ... jeweils in Kraft treten. Für international ... länger um das "ob", sondern darum, "wann" sie ...
Breaking Medicine Technology:David Dreyer Appointed to Diplomat Board of Directors 2Alere Applauds President's Executive Order Combating Antibiotic-Resistant Bacteria 2Pharma IQ stellt weltweite Serialisierungsfristen in seinen Countdown-Kalender 2014 - 2018 2
... 27 Data from a phase II study ... by increasing the frequency of bowel movements in ... analgesia. NKTR-118, an oral peripherally-acting opioid antagonist, ... for the treatment of opioid-induced constipation. ...
... Calif., Oct. 27 STAAR Surgical Company (Nasdaq: STAA ... ophthalmic products, today announced today that Deborah Andrews, Chief Financial ... at The Waldorf-Astoria Hotel on Wednesday, November 4th at 3:55 ... a live audio web cast of the presentation at ...
Cached Medicine Technology:Phase 2 Data From Oral NKTR-118 Presented at American College of Gastroenterology in San Diego 2Phase 2 Data From Oral NKTR-118 Presented at American College of Gastroenterology in San Diego 3Phase 2 Data From Oral NKTR-118 Presented at American College of Gastroenterology in San Diego 4
(Date:9/21/2014)... -- Young women starting college understand the benefits of ... eat. But they aren,t confident they can follow through ... study. The study involved 268 female college ... Exercising and Eating Right program. The students answered food-related ... if they were very busy with school work, were ...
(Date:9/21/2014)... To accommodate the ever-growing customer base, ... more trendy items. Recently, the company has unveiled its ... new and elegant wedding gowns, Angeldress.co.uk wants to make ... in an easy way. Its high quality vintage wedding ... 12% off to 62% off. , Online shopping is ...
(Date:9/21/2014)... (PRWEB) September 21, 2014 Recently, BambooIndustry.com, ... a special offer for its bamboo panels ( http://www.bambooindustry.com/products/bamboo-panel/ ... the market; all of them are available at discounted ... , The company’s discounted bamboo panels are ... made of quality materials. Each of them is finely ...
(Date:9/21/2014)... Top10BestSEOHosting.com, a leading review website, ... GreenGeeks are the most recommended hosting suppliers for ... quality hosting products. , “Don’t waste your ... recommend two great hosting companies to you,” the ... iPage and GreenGeeks are the most recommended suppliers ...
(Date:9/20/2014)... 6 Minutes to Skinny , a ... Ballantyne that is showing men and women of all ages ... body fat using simple 6-minute exercises and easy-to-follow lifestyle tips ... investigative review. , “When it comes to losing body ... out for all people,” reports Michaels. “Metabolism plays a big ...
Breaking Medicine News(10 mins):Health News: College Women Can Use Food Strategies, Study Finds 2Health News:Angeldress.co.uk Launches New Range Of 2014 Vintage Wedding Dresses In Its Online Store 2Health News:Discounted Bamboo Panels For Sale At BambooIndustry.com 2Health News:Leading Review Website Top10BestSEOHosting.com Unveils The Best Hosting Suppliers In September 2Health News:6 Minutes to Skinny: Review Exposes Craig Ballantyne’s Method to Jump Starting the Metabolism and Blasting Away Body Fat in Just 6 Minutes Per Day 2
... A disease called Onchocerciasis, river blindness or craw craw ... presents as a weakening// in affected individuals thus rendering ... turn adversely impacts the economy of this area. The ... is transmitted through the bite of the black fly, ...
... issued serious warnings against the use of products containing ... , These products are mainly sold to treat the ... highly corrosive and consuming them leads to stomach irritation ... Administration also said that intravenous injections of such products ...
... study published in the British Journal of Psychology showed that ... team of psychologist who wanted to test their theory linking ... hungry men preferred heavier women. ,Dr Viren ... Martin Tovee from Newcastle University conducted the study among 60 ...
... the Indian Space Research Organisation (ISRO) has said that there ... make it easier for detecting sensitive diseases. Mr Nair was ... CT scanner at Narayana Hrudayalaya at Bangalore. ,"Almost all ... context that early detection of heart disease gains importance," he ...
... According to the third phase of clinical trail conducted by ... that a weekly dose of erythropoietin //(EPO) is a very ... during chemotherapy. ,EPO is a natural hormone that ... red blood cell (RBC) transfusions in these children. This ...
... vehicle for delivering radioactive iodine dose to cure deadly ... ,Synthetic scorpion venom is used as carriers for ... is successfully complete and was conducted by under Adam ... Maxine Dunitz Neurosurgical Institute. About 18 patients participated in ...
Cached Medicine News:Health News:Onchocerciasis: Presentation And Treatment 2Health News:EPO Effective For Cancer Patients Suffering From Anemia 2Health News:New Carrier Developed To Deliver Drugs to Gliomas 2Health News:New Carrier Developed To Deliver Drugs to Gliomas 3
Inquire...
The Onar®Lp test system is an in vitro test for the qualitative diagnosis of legionella in clinical samples....
... is a blower-based, bi-level positive pressure ventilator ... weighing 30 kg or more. The KnightStar ... insufficiency and/or obstructive sleep apnea in the ... KnightStar 330 Ventilator includes a 3-30 cm ...
... The BiPAP Pro with Bi-Flex bi-level system, ... that the BiPAP Pro takes to change ... Digital Auto-Trak Sensitivity™ which automatically triggers the ... pressures based on the patients breathing rhythm. ...
Medicine Products: