Navigation Links
BioLineRx Announces Publication of Positive Pre-Clinical Results for BL-8040 in Treatment of Thrombocytopenia
Date:8/5/2013

sly developed under the name BKT-140.

About Thrombocytopenia
Thrombocytopenia refers to reduced platelet production in the bone marrow and its accompanying peripheral blood. It is a challenging clinical scenario induced by a multitude of reasons, and commonly encountered among oncologic patients receiving high doses of chemotherapy. Thrombocytopenia increases risk of bleeding, and in severe cases is life threatening. In patients with a very low platelet count or in cases presenting with severe bleeding, the standard of care remains platelet transfusion, a costly procedure with associated risks due to immune reaction to the transfused cells and due to possible contaminating pathogens. It is therefore crucial to uncover novel therapeutic approaches that will reduce reliance on blood products.

One promising approach is to try and augment bone marrow platelet production and release prior to (or concomitant with) the administration of chemotherapeutic drugs. Previous research has suggested that stimulation of the TPO/thrombopoietin-receptor pathway, which is considered the master regulator of megakaryocyte production, may be an attractive strategy for increasing platelet count. However, the clinical effectiveness of TPO and TPO-related drugs in preventing bleeding and platelet transfusions, as well as their side effect profile, remain serious issues for concern. Thus, alternative pathways are continuously being explored.

About BioLineRx
BioLineRx is a publicly-traded biopharmaceutical development company. BioLineRx is dedicated to building a portfolio of products for unmet medical needs or with advantages over currently available therapies. BioLineRx's current portfolio consists of seven clinical stage candidates: BL-1040, for prevention of pathological cardiac remodeling following a myocardial infarction, which has been out-licensed to Ikaria Inc., is currently undergoing a pivotal CE-Mark registration trial; BL-5010 for non-surgical remov
'/>"/>

SOURCE BioLineRx
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
2. Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012
3. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
4. Misonix Announces New Distribution Agreement For Panama
5. University of Maryland BioPark Announces MedImmunes Dr. Bahija Jallal as Newest Member of Board of Directors for UM Health Sciences Research Park
6. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
7. Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter
8. Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
9. Masimo Announces New Low-Profile Infant and Neonatal Pulse Oximetry Sensors
10. Anthera Announces the Completion of Patient Dosing in Phase 2b PEARL-SC Study
11. STAAR Surgical Announces First Quarter 2012 Results Release Date and Conference Call and Webcast
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/2/2014)... 2014 Reportbuyer.com has added a new ... Technologies for Molecular Imaging Devices ... The objectives of this study are to ... used for diagnostic purposes, present global market measurements ... market segments as well as forecast market and ...
(Date:9/2/2014)... , Sept. 2, 2014 Reportlinker.com ... available in its catalogue: Asia-Pacific ... http://www.reportlinker.com/p02353210/Asia-Pacific-Infusion-Therapy-Device-Market.html Abstract: The ... therapy devices included volumetric infusion pumps, syringe infusion ... connectors and stopcocks. These categories are segmented based ...
(Date:9/2/2014)... 2, 2014 The Pharmaceutical Care Management Association ... (PBMs), today filed a lawsuit in Iowa ... Iowa law that restricts tools used ... state,s employers and consumers.  The law—HF ... restricting the use of Maximum Allowable Cost (MAC) lists ...
Breaking Medicine Technology:Global Markets and Technologies for Molecular Imaging Devices 2Global Markets and Technologies for Molecular Imaging Devices 3Global Markets and Technologies for Molecular Imaging Devices 4Global Markets and Technologies for Molecular Imaging Devices 5Global Markets and Technologies for Molecular Imaging Devices 6Global Markets and Technologies for Molecular Imaging Devices 7Global Markets and Technologies for Molecular Imaging Devices 8Global Markets and Technologies for Molecular Imaging Devices 9Global Markets and Technologies for Molecular Imaging Devices 10Global Markets and Technologies for Molecular Imaging Devices 11Global Markets and Technologies for Molecular Imaging Devices 12Global Markets and Technologies for Molecular Imaging Devices 13Global Markets and Technologies for Molecular Imaging Devices 14Global Markets and Technologies for Molecular Imaging Devices 15Global Markets and Technologies for Molecular Imaging Devices 16Global Markets and Technologies for Molecular Imaging Devices 17Global Markets and Technologies for Molecular Imaging Devices 18Global Markets and Technologies for Molecular Imaging Devices 19Global Markets and Technologies for Molecular Imaging Devices 20Global Markets and Technologies for Molecular Imaging Devices 21Global Markets and Technologies for Molecular Imaging Devices 22Global Markets and Technologies for Molecular Imaging Devices 23Global Markets and Technologies for Molecular Imaging Devices 24Global Markets and Technologies for Molecular Imaging Devices 25Asia-Pacific Infusion Therapy Device Market 2Asia-Pacific Infusion Therapy Device Market 3Asia-Pacific Infusion Therapy Device Market 4Asia-Pacific Infusion Therapy Device Market 5Asia-Pacific Infusion Therapy Device Market 6Asia-Pacific Infusion Therapy Device Market 7Asia-Pacific Infusion Therapy Device Market 8Asia-Pacific Infusion Therapy Device Market 9Asia-Pacific Infusion Therapy Device Market 10Asia-Pacific Infusion Therapy Device Market 11Asia-Pacific Infusion Therapy Device Market 12
... ZURICH, December 9, 2011 NHS National ... ALFApump System Sequana Medical announced today the ... System commissioned by the National Innovation Centre, the NHS ... up the development and use of innovations that will ...
... ATLANTA, Dec. 8, 2011 CardioMEMS announced today that ... Devices advisory panel voted against the Champion Heart Failure ... allows cardiologists to monitor heart failure patients from their ... is safe with a vote of 9-1, the majority ...
Cached Medicine Technology:NHS National Innovation Centre Estimates Sequana Medical's ALFApump® System Could Save the NHS £50 Million in ascites Care Annually 2FDA Advisory Panel Recommends Against Approval of Champion® Heart Failure Management System for Patients With Heart Failure 2FDA Advisory Panel Recommends Against Approval of Champion® Heart Failure Management System for Patients With Heart Failure 3
(Date:9/2/2014)... SC (PRWEB) September 02, 2014 The Wm. ... outreach fair and public town hall meeting for Veterans and ... available at the outreach fair to provide Veterans with valuable ... McMurry. “The town hall will provide a forum where we ... VA programs.” , The outreach fair will be held 4:45 ...
(Date:9/2/2014)... with lumpectomy followed by radiation therapy survived as ... to a large study conducted by researchers at ... Cancer Prevention Institute of California. , The comprehensive ... disease is the first to directly compare survival ... bilateral mastectomy (the removal of both breasts), unilateral ...
(Date:9/2/2014)... for their own spread throughout the body by coaxing ... according to a new report by Johns Hopkins scientists. ... Nature Communications , the researchers describe animal and cell-culture ... released by breast cancer cells. These molecules cause lymphatic ... to produce proteins called CCL5 and VEGF. CCL5 attracts ...
(Date:9/2/2014)... The Dream2Walk Foundation along with Gas Monkey Bar and ... Spinal Cord Injury Awareness Month featuring full band performances by ... Linear Automotive will be there hosting a Hot Rod, Rat ... 2pm. The car show is Pre 1964 only, with a ... concert. There will be trophies for top 3 and best ...
(Date:9/2/2014)... TUESDAY, Sept. 2, 2014 (HealthDay News) -- Two new ... One suggests that 6-year-olds who were breast-fed have a ... to bottle-fed infants, while the other finds a similar ... upholds the "many benefits of breast-feeding in the immediate ... Lenox Hill Hospital in New York City. She was ...
Breaking Medicine News(10 mins):Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 2Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 3Health News:Breast cancer patients with bilateral mastectomy don't have better survival rates 4Health News:‘Prepped’ by tumor cells, lymphatic cells encourage breast cancer cells to spread 2Health News:Gas Monkey Hosts Concert in Dallas Benefiting Dream2Walk Foundation with Linear Automotive 2Health News:More Evidence Breast-Feeding Lowers Child's Risk of Infections, Allergies 2
... HOUSTON - A genetic mutation that drives the initiation ... tumor growth and progression, scientists report in the journal ... the Kras oncogene opens up a new category of ... proved difficult to attack directly, said study co-lead author ...
... THURSDAY, April 26 (HealthDay News) -- Dogs who accidentally eat ... emit a toxic gas that can sicken veterinary staff, ... for Disease Control and Prevention say such canine gas attacks ... and such incidents "might be underreported." All of the ...
... issue of the journal Neurology , researchers at ... a simple, unobtrusive wrist sensor could gauge the severity ... but without the ungainly scalp electrodes and electrical ... clinically useful data from epilepsy patients as they go ...
... from University Hospitals (UH) Case Medical Center and Case ... findings that mammography remains beneficial for women in their ... issue of American Journal of Roentgenology , women ... mammography were diagnosed at earlier stages with smaller tumors ...
... , WEDNESDAY, April 25 (HealthDay News) -- When patients ... risk goes up quickly, new research finds. That ... warfarin or a newer, more expensive drug, Xarelto (rivaroxaban). ... which the upper chambers of the heart quiver or ...
... , WEDNESDAY, April 25 (HealthDay News) -- Heroin ... this sensitivity does not subside over the course of ... Researchers from the University of California-Los Angeles sought ... hyperalgesia) might change as a heroin addict moves from ...
Cached Medicine News:Health News:Mutant Kras drives pancreatic cancer maintenance via metabolic pathways 2Health News:Mutant Kras drives pancreatic cancer maintenance via metabolic pathways 3Health News:Mutant Kras drives pancreatic cancer maintenance via metabolic pathways 4Health News:Toxic Gas in Dogs' Vomit a Threat to Vets: CDC 2Health News:Gauging seizures' severity 2Health News:Gauging seizures' severity 3Health News:Study finds mammography beneficial for younger women 2Health News:Stopping Blood Thinners Raises Stroke Risk for Patients With Irregular Heartbeat 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
Medicine Products: