Navigation Links
BioLineRx Announces Publication of Positive Pre-Clinical Results for BL-8040 in Treatment of Thrombocytopenia
Date:8/5/2013

sly developed under the name BKT-140.

About Thrombocytopenia
Thrombocytopenia refers to reduced platelet production in the bone marrow and its accompanying peripheral blood. It is a challenging clinical scenario induced by a multitude of reasons, and commonly encountered among oncologic patients receiving high doses of chemotherapy. Thrombocytopenia increases risk of bleeding, and in severe cases is life threatening. In patients with a very low platelet count or in cases presenting with severe bleeding, the standard of care remains platelet transfusion, a costly procedure with associated risks due to immune reaction to the transfused cells and due to possible contaminating pathogens. It is therefore crucial to uncover novel therapeutic approaches that will reduce reliance on blood products.

One promising approach is to try and augment bone marrow platelet production and release prior to (or concomitant with) the administration of chemotherapeutic drugs. Previous research has suggested that stimulation of the TPO/thrombopoietin-receptor pathway, which is considered the master regulator of megakaryocyte production, may be an attractive strategy for increasing platelet count. However, the clinical effectiveness of TPO and TPO-related drugs in preventing bleeding and platelet transfusions, as well as their side effect profile, remain serious issues for concern. Thus, alternative pathways are continuously being explored.

About BioLineRx
BioLineRx is a publicly-traded biopharmaceutical development company. BioLineRx is dedicated to building a portfolio of products for unmet medical needs or with advantages over currently available therapies. BioLineRx's current portfolio consists of seven clinical stage candidates: BL-1040, for prevention of pathological cardiac remodeling following a myocardial infarction, which has been out-licensed to Ikaria Inc., is currently undergoing a pivotal CE-Mark registration trial; BL-5010 for non-surgical remov
'/>"/>

SOURCE BioLineRx
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Precision Optics Corporation Announces $1 Million Order for Microprecision™ Based Endoscopes
2. Young Innovations, Inc. Announces Record Sales and EPS for the Quarter Ended March 31, 2012
3. JDRF Announces Research Collaboration with Dexcom, Inc. to Develop "Smart Transmitter" Technology to Accelerate Artificial Pancreas Studies
4. Misonix Announces New Distribution Agreement For Panama
5. University of Maryland BioPark Announces MedImmunes Dr. Bahija Jallal as Newest Member of Board of Directors for UM Health Sciences Research Park
6. Novelos Therapeutics Announces Successful Completion of First Cohort In Lung Cancer Trial With I-124-CLR1404 (LIGHT) Cancer-Targeted PET Imaging Agent at UW Carbone Cancer Center
7. Boston Scientific Announces CE Mark and European Launch of Emerge™ PTCA Dilatation Catheter
8. Soligenix Announces Further Progress with ThermoVax™ for Long-Term Vaccine ThermoStability
9. Masimo Announces New Low-Profile Infant and Neonatal Pulse Oximetry Sensors
10. Anthera Announces the Completion of Patient Dosing in Phase 2b PEARL-SC Study
11. STAAR Surgical Announces First Quarter 2012 Results Release Date and Conference Call and Webcast
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... -- Cohen, Placitella & Roth, PC is investigating potential ... Pharmaceutical Corporation ("Nymox" or "Company") (NASDAQ: ... 2011 through November 2, 2014 ("Class Period").  The ... officers and directors publically disseminated materially false and/or ... 20(a) of the Securities Exchange Act of 1934 ...
(Date:11/26/2014)... Md. , Nov. 26, 2014  Over 100 ... of those suffer from this pain daily. Chronic and ... of pain management is born to fulfill the need ... all types of pain. On October 28th, ... the Cumberland, Maryland community.  This ...
(Date:11/26/2014)... -- Zynerba Pharmaceuticals , Inc., a specialty pharmaceutical ... cannabinoid treatments, today announced that the company will present ... The conference will be held December 2 to 3, ... York . Zynerba,s Chairman and CEO, Armando ... December 2. To listen to a webcast ...
Breaking Medicine Technology:Cohen, Placitella & Roth, PC Investigating Nymox Pharmaceutical Corporation for Failing to Disclose Material Information 2Cohen, Placitella & Roth, PC Investigating Nymox Pharmaceutical Corporation for Failing to Disclose Material Information 3New Pain Management Center Opens in Cumberland, Md. 2Zynerba Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2014 2
... Inc. ("Oncolytics") (TSX:ONC, NASDAQ: ONCY ) announced ... a Phase 2 clinical trial using intravenous administration ... in patients with non-small cell lung cancer (NSCLC) ... is Dr. Miguel Villalona-Calero, Professor, Division of Hematology/Oncology ...
... quantitative imaging endpoints from MRI analysesROCHESTER, N.Y., March ... ), a leading provider of quantitative imaging for ... Canadian medical device company based in Laval, Quebec, ... pivotal clinical trial for its cartilage repair device ...
Cached Medicine Technology:Oncolytics Biotech(R) Inc. Announces Start of Enrolment in U.S. Phase 2 Combination Clinical Trial for Non-Small Cell Lung Cancer Patients with K-RAS or EGFR-Activated Tumours 2VirtualScopics' Quantitative Imaging Provides Primary Endpoint in Cartilage Repair Pivotal Clinical Trial 2VirtualScopics' Quantitative Imaging Provides Primary Endpoint in Cartilage Repair Pivotal Clinical Trial 3
(Date:11/28/2014)... a leader in the wig industry, has announced a great ... promotion features: , > 400 pieces of FOUR ... (no coupon code needed), > 10% off for ... $49 , Visit http://www.uniwigs.com for more details , The ... 1st and the first 100 shoppers each day will receive our ...
(Date:11/28/2014)... Georgia (PRWEB) November 28, 2014 Patten ... and locally grown. With those passions driving them, they've ... Georgia Grown. Having tried other pecans oils, they've found ... Pitts, Georgia to be exceptionally flavorful, retaining the buttery ... The same nutritional benefits found in pecans ...
(Date:11/28/2014)... (PRWEB) November 28, 2014 An inventor from ... day to day. "I got this idea while lying in ... the bathroom," he said. , The Bed Buddy provides a ... go to the bathroom. It eliminates the need to leave ... promotes comfort and dignity. Easy to use and producible in ...
(Date:11/28/2014)... Before that Thanksgiving meal even had time to ... shopping season. Today, people will stand in line for hours ... retail shopping day of the year. , But instead ... Albany dentist Dr. Ronald Receveur is asking the public ... literally brighten a few smiles. , The gifts he suggests ...
(Date:11/28/2014)... Colorado (PRWEB) November 28, 2014 talklocal ... connect consumers to the right service professionals by phone in ... week after at least two tornadoes were reported to have ... Although no damage was reported following the tornadoes, Denver residents ... for the unexpected. Having TalkLocal is like having local pros ...
Breaking Medicine News(10 mins):Health News:Pre-X'mas Crazy Sale Starts from $0 at UniWigs.com 2Health News:Patten Pecans Goes Local with Nutritious Georgia Pecan Oil 2Health News:New Albany Dentist Offers Gift Ideas That Can Improve Oral Health 2Health News:New Albany Dentist Offers Gift Ideas That Can Improve Oral Health 3Health News:New Albany Dentist Offers Gift Ideas That Can Improve Oral Health 4Health News:TalkLocal Launches In Denver A Week After Multiple Tornadoes Hit Near City 2
... Yet another Major Rise in Listeners. Affordable Health Insurance and ... ... Kansas City, MO (PRWEB) August 28, 2008 -- The Health Insurance ... September 6th on 1260 AM and 104.1 FM KSGF. The ...
... RDYN ) today announced the restructuring of ... 80% to 5 employees in,actions that are scheduled ... As a result of these actions Replidyne will ... for the,treatment of Clostridium difficile (C. difficile) bacteria ...
... Oncology has selected renowned pediatric oncologist Audrey Evans, M.D., ... recognized during the Awards Ceremony held Tuesday, September 23, ... Boston., Dr. Evans has been on the forefront of ... She was one of the co-founders of the original ...
... longer to see positive effect, researchers say , , WEDNESDAY, Aug. ... not lower the rate of stroke, cardiovascular events or diabetes ... stroke, a new study finds. , Telmisartan is an angiotensin ... chemicals that constrict the blood vessels enabling the blood to ...
... wages and benefits, HEMET, Calif., Aug. 27 The ... against the,board of directors of Valley Health System (VHS) for ... already voted to agree to., "I do this job ... said,Lisa Howell, a registered nurse at Menifee Valley Medical Center. ...
... use 7 simple variables to gauge in-hospital mortality ... News) -- A new scoring system for assessing ... been confirmed to be effective, according to Mayo ... The Mayo Clinic Risk Score (MCRS) uses seven ...
Cached Medicine News:Health News:The Health Insurance Advocate Radio Show Expands to Springfield, Missouri, and Reaches a New All-Time Ratings High for Female Listenership 2Health News:The Health Insurance Advocate Radio Show Expands to Springfield, Missouri, and Reaches a New All-Time Ratings High for Female Listenership 3Health News:Replidyne Announces Restructuring of Operations 2Health News:ASTRO selects pediatric oncologist as 2008 honorary member 2Health News:Newer Blood Pressure Drug No Better Than Placebo in Preventing Stroke 2Health News:Newer Blood Pressure Drug No Better Than Placebo in Preventing Stroke 3Health News:State Board Issues Complaint: VHS Board Should Have Signed Contract With Caregivers 2Health News:Angioplasty Scoring System Predicts Risk of Death 2
20 g MVR knife. Dimensions: 31.8 mm x 1.18 mm x 2.7 mm....
Full Handle Laseredge Spoon Blade Knife, 3.0 mm angled double bevel. Blade dimension: 11.0 mm (L) x 3.0 mm (W). Cut: 320....
Full Handle Laseredge Slit Blade Knife, 3.2 mm angled double bevel. Blade tip dimension: 14.4 mm x 3.2 mm x 4.0 mm....
Full Handle Laseredge Slit Blade Knife, 3.0 mm angled bevel up. Blade tip dimension: 14.4 mm x 3.0 mm x 3.7 mm....
Medicine Products: