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BioLineRx Announces New Positive Results in Phase 2a trial for Orally Available Inflammatory Bowel Disease Treatment
Date:11/26/2013

-9). It also acts as a specific suppressor of acetylcholinesterase, a key enzyme involved in neurological pathways. This dual effect enables a unique combination of both neurological and anti-inflammatory properties. In addition, BL-7040 has an indirect effect on the production of pro-inflammatory cytokines as well as anti-inflammatory properties via modulation of macrophages. BL-7040 was invented by Prof. Hermona Soreq from the Hebrew University of Jerusalem, and is being developed by BioLineRx under a worldwide exclusive license from Yissum Research and Development Company, the technology transfer company of the Hebrew University.

About Inflammatory Bowel Disease (IBD)              
Inflammatory bowel disease is a chronic inflammatory gastrointestinal disease characterized by chronic abdominal pain, discomfort, bloating and alteration of bowel habits. Over two million people are afflicted with IBD in the seven major markets. Sales of existing drugs in the seven major markets were estimated at over $7.5 billion in 2012, of which $5.6 billion were US-based sales. By 2020, sales in the seven major markets are expected to be over $8 billion, of which $6.5 billion are expected to be in the US. Despite these numbers, there is still a significant portion of IBD patients who are underserved by current pharmacological treatments.

About BioLineRx        
BioLineRx is a publicly-traded biopharmaceutical development company dedicated to building a portfolio of products for unmet medical needs, as well as those with advantages over currently available therapies. The Company in-licenses novel compounds primarily from academic institutions and biotech companies based in Israel, develops them through pre-clinical and/or clinical stages,
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5. BioLineRx Receives Regulatory Approval to Commence Phase 1/2 Trial for Novel Treatment of Celiac Disease
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