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BioLife Solutions Congratulates DCPrime on Its Approved Orphan Medicinal Product Application for DCOne™ Leukemia Vaccine
Date:2/6/2012

on of cell-based products continues to evolve and become more strenuous for our customers."

Kruisbeek continued, "Finding a clinical grade freeze media for DCPrime's final vaccine dose was a high priority. We considered the cost and quality aspects of formulating a freeze media in-house against selecting a pre-formulated GMP manufactured commercial product, and completed a series of comparative experiments.  CryoStor clearly outperformed all other formulations in biopreservation efficacy, and its serum-free, protein-free formulation supported our quality requirements."

About DCPrimeDCPrime is a Dutch clinical stage company, dedicated to developing cancer vaccines based on its proprietary dendritic cell (DC) technology platform DCOne™. With this platform, the company can generate off‐the‐shelf DC‐based vaccines for a broad range of cancer types. DCOne‐based DC vaccines share all immune‐stimulatory properties with patient derived DC‐based vaccines, and have the simple logistics of off‐the‐shelf products. A commercial scale manufacturing process to produce DCOne‐based vaccines has been developed, and DCPrime's lead product DCP‐001 is in the clinic in a Phase I/IIa study in patients with Acute Myeloid Leukemia (AML). Several products for solid cancers are in preclinical development, using peptide loaded DCOne‐based vaccines. With this powerful platform, DCPrime has the opportunity to become the gold standard for off‐the‐shelf dendritic cell products.

About BioLife SolutionsBioLife Solutions develops, manufactures and markets patented hypothermic storage and cryopreservation solutions for cells and tissues.  The Company's proprietary HypoThermosol® and CryoStor® platform of solutions are marketed to academic and commercial organizations involved in cell th
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