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BioCryst Updates Peramivir Clinical Development Plan
Date:1/23/2008

d life-threatening influenza. In the United States, intravenous peramivir injection has received Fast Track designation from the Food and Drug Administration (FDA).

About Influenza

The influenza virus causes an acute viral disease of the respiratory tract. Unlike the common cold and some other respiratory infections, seasonal influenza can cause severe illness, resulting in life-threatening complications. According to the Centers for Disease Control and Prevention, every year in the United States as many as 750,000 people are hospitalized due to influenza or its complications, and of this number, an estimated 40,000 people die each year. Most at risk are young children, the elderly, and people with seriously compromised immune systems.

Avian influenza A viruses of H5N1 subtype are circulating among birds worldwide. The virus is considered extremely contagious in fowl. It is believed that all species of birds are susceptible to avian influenza, but domestic poultry, including chickens and turkeys, are among the more susceptible to the highly pathogenic strain. According to the World Health Organization, as of December 2007 at least 331 people have been infected with H5N1 avian influenza, of which at least 200 have died. Almost all of these infections are believed to have resulted from contact with infected poultry.

About BioCryst

BioCryst Pharmaceuticals, Inc. is a leader in the use of crystallography and structure-based drug design for the development of novel therapeutics to treat cancer, cardiovascular diseases, autoimmune diseases, and viral infections. The Company is advancing multiple internal programs toward potential commercialization including forodesine HCl in oncology, BCX-4208 in transplantation and autoimmune diseases and peramivir in seasonal and life- threatening influenza. BioCryst has a worldwide partnership with Roche for the development and commercialization of BCX-4208, and is collaborating with Mundipharma for t
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SOURCE BioCryst Pharmaceuticals, Inc.
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