Navigation Links
BioCryst Updates Peramivir Clinical Development Plan
Date:1/23/2008

BIRMINGHAM, Ala., Jan. 23 /PRNewswire-FirstCall/ -- BioCryst Pharmaceuticals, Inc. (Nasdaq: BCRX) today provided an update on activities conducted following release of the preliminary Phase II data and outlined the resulting clinical development plan for intramuscular (i.m.) peramivir.

(Logo: http://www.newscom.com/cgi-bin/prnh/20030414/BIOCRYSTLOGO )

Following release of preliminary Phase II results in September 2007, the Company completed additional analyses of the clinical data and performed a preliminary analysis of the virologic data from this trial. The Company also conducted further pharmacokinetic (PK) studies in healthy volunteers and has had discussions with the FDA and The Department of Health and Human Services (HHS) in support of the continuing development of peramivir.

Preliminary analysis of the virologic data from the Phase II trial indicated that i.m. peramivir demonstrated statistically significant reductions in influenza virus shedding in both active treatment groups when compared to placebo, with greater reductions in the 300mg group (p<0.001). Additionally, pharmacokinetic studies have been completed that indicate that needle length impacts adequate and consistent systemic exposure to i.m. peramivir. These PK studies also provide guidance on the appropriate needle length to use in future studies to provide adequate drug exposure for subjects based upon an individual's body mass index (BMI) and gender.

Based on these clinical results and virologic data, the Company believes that a single i.m. dose of 300mg peramivir can be a potentially clinically effective dose. Given the dose-response observed between the
'/>"/>

SOURCE BioCryst Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. BioCryst Initiates Enrollment in Pivotal Trial of Forodesine HCL in Patients with Cutaneous T-Cell Lymphoma (CTCL)
2. BioCryst Provides Forodesine HCl Update
3. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
4. Diamyd Updates Gene Therapy Program and Outlines Plans for Phase I Clinical Trial for Treatment of Cancer Pain
5. Alfacell Updates Status of ONCONASE(R) Phase III Clinical Program
6. Wyeth Presents New Phase 3 Data and Updates Regulatory Timing for NDA Filing of Bazedoxifene/Conjugated Estrogens
7. Alliance Pharmaceutical Corp. Updates Oxygent(TM) Clinical Development Plan
8. Imaging Diagnostic Systems Updates PMA Filing Status for the New CT Laser Breast Imaging System
9. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
10. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
11. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... , April 17, 2015 ... Market Research Report on Global and China Lysine ... is a professional and the deep research report ... introduces Lysine basic information including definition, classification specifications, ... as US, Europe , ...
(Date:4/17/2015)... and Markets ( http://www.researchandmarkets.com/research/lmsnqn/medical_equipment ) has announced ... Leasing - Global Strategic Business Report" report to ... markets for Medical Equipment Rental and Leasing in US$ ... US, Japan , Europe ... estimates and forecasts are provided for the period 2014 ...
(Date:4/17/2015)... 17, 2015 Research and Markets ( ... "Mammography Equipment - Global Strategic Business Report" report ... worldwide markets for Mammography Equipment in US$ Thousands by ... Mammography Equipment. The report provides separate comprehensive analytics for ... Japan , Europe , ...
Breaking Medicine Technology:Lysine Market International (US, Europe, Japan) Research Analysis 2Lysine Market International (US, Europe, Japan) Research Analysis 3Lysine Market International (US, Europe, Japan) Research Analysis 4Lysine Market International (US, Europe, Japan) Research Analysis 5Medical Equipment Rental and Leasing Market 2015-2020 - Global Strategic Business Report - Healthcare Spending Slowdown Bodes Well for Medical Equipment Leasing 2Mammography Equipment (Analog & Digital) Market 2015-2020 - Global Strategic Business Report: Breast Imaging Screening Programs Push Sales 2
(Date:4/18/2015)... 2015 "I recognized the need for ... facilities," said an inventor from Cincinnati, Ohio. "This need ... He developed the Slyde Door to offer an alternative ... facilities. It provides convenient storage space for an evacuation ... available for patients. , This offers added peace ...
(Date:4/18/2015)... 2015 Lower-auto-insurance.com has released a new ... auto insurance quotes . , Drivers can find ... quotes. A professional insurance brokerage website can help drivers ... a simple, convenient way. The whole process is designed ... , Comparing online car insurance quotes is advantageous because ...
(Date:4/18/2015)... NY (PRWEB) April 18, 2015 On April ... Security Threat Report , which they say, “exposes a tactical ... many new malware variants were introduced in 2014 - almost ... for Zero Day threats to be identified and patched by ... is abundantly clear that doing business in a digital world ...
(Date:4/17/2015)... Heritage Woods of McLeansboro, a Gardant affordable assisted ... on April 20 with a day full of activities ... soul. , The community, which is located at 605 ... all incomes, including those on Medicaid, who need some ... is observed every April and highlights the communities within ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 Alcohol and ... Dependence (NCADD) notes that drinking and driving has been ... At the same time, the link between alcohol and ... domestic abuse and violence and sexual assault, and their ... to the NCADD, 5.3 million adults in America were ...
Breaking Medicine News(10 mins):Health News:Auto Insurance Quotes Can Provide Accurate Results! 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 3Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 4Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 5Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 2Health News:Heritage Woods of McLeansboro Affordable Assisted Living to Celebrate Supportive Living Week 3Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 2Health News:Narconon Arrowhead Raises Awareness on Alcohol Related Prevention 3
... Hospital Teams with RWD(R) Healthcare Practice to Streamline Patient ... a time when some hospitals are struggling financially, St. ... by focusing on efficient patient care with quality at ... care, St. Luke,s is streamlining its transfer process for ...
... an alliance of businesses in Bucks County, Pa. have ... staff more time to devote to patient care. This ... doctors in Bucks County better handle the cumbersome and ... the Bucks County Partners include Doylestown Hospital, Fox Rothschild ...
... announce positive results for the CriticalPoint training program ... national survey.ENGLEWOOD, Colo., May 13 Baxa Corporation ... online and on-demand training program, CriticalPoint, in a ... in 9% of the facilities surveyed by ...
... students receive $10,000 scholarships to help with escalating ... an effort to promote diversity and help with ... American Medical Association (AMA) Foundation has presented 12 ... $10,000 Minority Scholars Awards.The awards recognize scholastic achievement, ...
... HUNTINGTON BEACH, Calif., May 13 The coverage of ... WorldNet ( http://HealthWorldNet.com ) provides ... year ago, HealthWorldNet.com (HWN) is the fastest-growing, HON-certified and ... into one of the largest and most comprehensive web ...
... holds its third Public Policy Day in Washington, D.C. LITTLE ... America (CMSA) held its third annual Public Policy Day on ... management and the vital care coordination services case managers perform ... services can support federal health care reform efforts."Case management is ...
Cached Medicine News:Health News:St. Luke's Episcopal Hospital Announces Latest Phase of Efficiency, Excellence and Engagement Campaign 2Health News:St. Luke's Episcopal Hospital Announces Latest Phase of Efficiency, Excellence and Engagement Campaign 3Health News:St. Luke's Episcopal Hospital Announces Latest Phase of Efficiency, Excellence and Engagement Campaign 4Health News:Physicians Practice and Area Businesses Partner to Improve Patient Care in Bucks County, Pennsylvania 2Health News:Physicians Practice and Area Businesses Partner to Improve Patient Care in Bucks County, Pennsylvania 3Health News:Physicians Practice and Area Businesses Partner to Improve Patient Care in Bucks County, Pennsylvania 4Health News:CriticalPoint(TM) Training Rated 'Excellent' in Customer Satisfaction 2Health News:CriticalPoint(TM) Training Rated 'Excellent' in Customer Satisfaction 3Health News:AMA Foundation Names Minority Scholars Award Recipients 2Health News:HealthWorldNet.com Announces HealthWiNs Awards 2Health News:CMSA Delivers Important Message to Congress: Case Management Services Improve Patient Care and Should Be Key Strategy in Health Care Reform Initiatives 2Health News:CMSA Delivers Important Message to Congress: Case Management Services Improve Patient Care and Should Be Key Strategy in Health Care Reform Initiatives 3
... facilitates fast and effective resection of meniscal ... meniscal rim. The flat, crescent-shaped tip has ... the tightest joint spaces. Made in the ... of engineering experience in arthroscopy hand instrument ...
... facilitates fast and effective resection of meniscal ... meniscal rim. The flat, crescent-shaped tip has ... the tightest joint spaces. Made in the ... of engineering experience in arthroscopy hand instrument ...
... The WideBiter Punch series facilitates fast ... recreating a smooth, anatomically shaped meniscal rim. ... low profile to access even the tightest ... Arthrex California, Inc., 20 years of engineering ...
... series facilitates fast and effective resection of ... shaped meniscal rim. The flat, crescent-shaped tip ... even the tightest joint spaces. Made in ... years of engineering experience in arthroscopy hand ...
Medicine Products: