Navigation Links
Bexion Pharmaceuticals Continues to Gain Support from National Cancer Institute (NCI)
Date:10/8/2010

COVINGTON, Ky., Oct. 8 /PRNewswire/ -- Bexion Pharmaceuticals announced today that it has been awarded a $1.5M Phase II Small Business Innovation Research (SBIR) grant by the National Cancer Institute (NCI). The grant entitled "SapC-DOPS Nanovesicles for Treating Glioblastoma Multiforme" was awarded September 28, 2010 and covers a two year period.  This announcement from NCI follows their September 20, 2010 announcement selecting Bexion for a notable research collaboration with NCI's Nanotechnology Characterization Laboratory (NCL), part of a major program, the Alliance for Nanotechnology in Cancer, to advance the medical applications of nanotechnology.

Bexion's proprietary technology is based on Saposin C- dioleoylphosphatidylserine (dubbed "SapC-DOPS") and is a first-in-class nanovesicle therapeutic for the treatment of glioblastomas (GBM), pancreatic cancers, and other solid tumors.  These nanovesicles have preferential affinity for phosphatidylserine-enriched membrane patches which appear to be common in many types of tumor cells and tumor neovasculature.  Bexion's initial studies of SapC-DOPS nanovesicles have shown that they induce apoptosis in cancer cell lines and also demonstrated in vivo efficacy in multiple tumor models.

The intent of this Phase II SBIR grant is to identify and select optimized SapC-DOPS formulations and treatment methods for glioblastoma multiforme, suitable for advancing Bexion's drug toward planned human testing. Upon the completion of these studies, Bexion expects to have compelling evidence to progress into clinical development.

"This Phase II award will expedite our goal to develop a new molecular entity with a novel mechanism of action for targeting and eliminating glioblastoma multiforme (GBM, high grade glioma), a deadly and invasive brain tumor with no effective treatment," stated Dr. Ray Takigiku, Bexion's co-founder and CEO. "Of the 12,000 patients expected to be diagnosed with GBM this y
'/>"/>

SOURCE Bexion Pharmaceuticals
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Onyx Pharmaceuticals Provides Status Update on Carfilzomib
2. Onyx Pharmaceuticals Announces Teleconference to Provide Status Update on Carfilzomib
3. Star Scientific Comments on Roskamp Institutes Plans to Conduct Human Alzheimers Clinical Trials Using a Compound (RCP-006) Developed by Rock Creek Pharmaceuticals, Inc.
4. VentiRx Pharmaceuticals Reports Positive Clinical Data for VTX-1463 in Allergic Rhinitis
5. Regeneron Pharmaceuticals, Inc. Announces The Sale of 4,500,000 Shares of Common Stock
6. Lotus Pharmaceuticals Retains Sichenzia Ross Friedman Ference LLP as General Legal Counsel
7. ISTA Pharmaceuticals Reports Positive Preliminary Results from its Phase 1/2 Clinical Study of Bepotastine Besilate Nasal Spray for the Treatment of Symptoms Associated with Seasonal Allergic Rhinitis
8. MAP Pharmaceuticals Announces Exercise of Over-Allotment Option and Closing of Underwritten Offering of Common Stock
9. Savient Pharmaceuticals Announces Dismissal of Class Action Lawsuit
10. Jiangbo Pharmaceuticals Announces Fourth Quarter and Fiscal Year 2010 Results
11. Transcept Pharmaceuticals to Present at BIO Investor Forum
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... , Jan. 15, 2014 Sono-Tek Corporation (OTC BB: SOTK) ... November 30, 2013, compared to sales of $2,202,000 for the ... again, this quarter has also shown growth over the preceding ... quarter of this fiscal year. Markets that experienced sales increases ...
(Date:1/15/2014)... 15, 2014 /PRNewswire-iReach/ -- ChinaMarketResearchReports.com adds "China Orthopedic Instrument ... (Photo: http://photos.prnewswire.com/prnh/20140115/MN46792 ) ... support, China,s orthopedic instrument industry ... market size rising from 3.28 billion yuan in 2006 ...
(Date:1/15/2014)... , Jan. 15, 2014 Most osteoporosis patients want ... a recent online survey* sponsored by Mission Pharmacal Company. ... National Osteoporosis Foundation online support community, revealed that 74 ... that comes in a form other than a pill ...
Breaking Medicine Technology:Sono-Tek Announces Third Quarter Results 2Sono-Tek Announces Third Quarter Results 3Sono-Tek Announces Third Quarter Results 4Orthopedic Instrument Industry in China Markets Forecast to 2015 2Orthopedic Instrument Industry in China Markets Forecast to 2015 3Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 2Mission Pharmacal Conducts Online Survey of Osteoporosis Patients 3
(Date:7/10/2014)... For decades, health-conscious people around the globe have taken ... this was one of the paths to good health ... trials of antioxidant supplements have repeatedly dashed the hopes ... cancer risk. Virtually all such trials have failed ... fact, in several trials antioxidant supplementation has been linked ...
(Date:7/10/2014)... Depressed men with localized prostate cancer were more ... cancer, received less effective treatments and survived for ... not depressed, a UCLA study has found. , ... several factors such as bias against the mentally ... depressed man,s lack of investment in his general ...
(Date:7/10/2014)... Bellvitge Biomedical Research Institute (IDIBELL) and the Catalan Institute ... a new therapeutic combination to combat resistant sarcomas. The ... could stabilize the growth of these tumors have been ... Cancer ., Sarcomas , Sarcomas are a rare ... subtypes. It can affect from children to older ages. ...
(Date:7/10/2014)... and cakes that are just as tempting as ... thanks to fresh insights into how proteins can ... , Funded by the Engineering and Physical ... University and the University of Edinburgh has produced ... and therefore closely mimic the behaviour of fats ...
(Date:7/10/2014)... new drug could prove useful in treating small cell lung ... Scientists from the Cancer Research UK Manchester Institute, based at ... Research Centre, teamed up with experts at AstraZeneca, as part ... known as AZD3965 - on small cell lung cancer ... Cancer Research , also helps identify which patients are most ...
Breaking Medicine News(10 mins):Health News:How antioxidants can accelerate cancers, and why they don't protect against them 2Health News:Depressed men with prostate cancer are diagnosed later stage, get less effective therapies 2Health News:New therapeutic combination to slow resistant sarcomas 2Health News:Great tasting low-fat cheeses and cakes could soon be on the menu 2Health News:New drug active against most aggressive type of lung cancer cells 2
... National Council on,Disability (NCD) today invited the Boston disability ... will take place at,the Hyatt Regency Boston, One Avenue ... 8:30 a.m. until 5:00 p.m.; Friday,November 30 from 8:30 ... a.m. until 11:15 a.m., Public comment sessions will ...
... IRVINE, Calif., Nov. 9 Masimo (Nasdaq: MASI ... Low Perfusion,pulse oximetry, announced today that the Pricing Committee ... rights plan. "This plan is designed to enhance ... acquire control of the company,that do not offer an ...
... N.C. and ALPHARETTA, Ga., Nov. 9 ... diagnostic imaging,services, officially joined Novant Health today ... acquisition. MedQuest will operate as a,wholly-owned subsidiary ... not-for-profit integrated healthcare system serving,North and South ...
... 9, 2007) A gender difference exists among surgeons ... the factors that may influence their career choice, according ... November issue of the Journal of the American College ... higher percentage of women than men were influenced by ...
... effective in easing pain, study finds , FRIDAY, Nov. 9 ... reduce disease activity and pain in patients with chronic active ... of 10 patients, average age 62, who had gout for ... by Dr. Robert Terkeltaub of the VA Medical Center and ...
... 8th annual gala and auction November 16 to benefit Girls ... to kayak, golf, run, bike,dine, relax, shop, travel and more ... Go Girl Gala, taking place Friday November 16 at the,Chicago ... and fitness enthusiasts, features live music from the Underwater,People, cocktails, ...
Cached Medicine News:Health News:Masimo Corporation Adopts Stockholder Rights Plan 2Health News:Masimo Corporation Adopts Stockholder Rights Plan 3Health News:Novant Health Completes Purchase of MedQuest 2Health News:Novant Health Completes Purchase of MedQuest 3Health News:Survey shows gender differences are factor when surgeons in training choose a subspecialty 2Health News:Chicago's Premier Sports and Fitness Auction is Back! 2
... System Produces Type I Water Directly from Tap, ... for scientists who need 5 to 15 L ... have easy access to acceptable quality pretreated water. ... L/min of ultrapure (Type I) water on demand, ...
... speed, stability and durability. Back-lighted Display. ... multiple units of measure, piece counting ... and GLP/GMP/ISO output including date and ... calibration with external weights only (selectable ...
... weighing mechanism for speed, stability and ... analog display modes, multiple units of ... functions, auto print, and GLP/GMP/ISO output ... built-in clock. Built-in, motor-driven internal ...
... - Battery Powered (6 size AA required). ... (g, ct, oz, ozt, GN, dwt, mom, ... and Percent Measure functions, Auto Print. Optional ... AC adapter may be ordered for AC ...
Medicine Products: