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Best of ASCO Features Two Studies Led by US Oncology Research Affiliated Physicians
Date:6/15/2011

ww.texasoncology.com/doctors/Frankie_Holmes/">Frankie Ann Holmes, MD, Texas Oncology – Houston Memorial City)

"This study is extremely exciting for three reasons," said Dr. Holmes. "First, it was a 'deep dive' into the molecular analysis of breast cancer, but it was carried out in the patients' own oncologist's office close to their home by US Oncology Research network doctors, not at a university or tertiary care center. Second, by biopsying the tumor before and after two weeks of treatment with a HER2-blocking medication, we were able to see changes in the levels of molecules that, in the end, correlated with whether the tumor completely disappeared or was resistant to the treatment. In the future, we hope testing each patient's tumor this way will tell us which treatment has the best chance of cure for each unique patient. Third, the patients in our trial were passionately committed as our partners in the research effort to cure breast cancer. The extra biopsies were a gift of their time and tissue, and the many new findings in our study are a tribute to them. Curing breast cancer, as with many other areas of life, 'takes a village.'"

- Abstract #1007: A randomized phase III study of iniparib (BSI-201) in combination with gemcitabine/carboplatin (G/C) in metastatic triple-negative breast cancer (TNBC). (Joyce O'Shaughnessy, MD, Texas Oncology - Baylor Charles A. Sammons Cancer Center.)

During the ASCO 47th Annual Meeting, 14 US Oncology Research affiliated studies were presented orally - four of which were presented by US Oncology Research affiliated physicians. In addition, McKesson Specialty Care Solutions | US Oncology affiliated investigators also contributed to several poster discussions, posters, trials in progress, and published studies. For a full list of these studies, see the

SOURCE US Oncology
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