Navigation Links
Berg Pharma presents at ASCO, poised to lead field in cancer metabolism with Phase II trials of BPM 31510
Date:6/12/2012

CAMBRIDGE, Mass., June 12, 2012 /PRNewswire/ -- Berg Pharma, a Boston-based pharmaceutical company presented at the 2012 American Society of Clinical Oncology meeting in Chicago on BPM 31510,  the lead molecule in the Berg's cancer portfolio that targets the metabolism of cancer cells by reversing the Warburg phenotype.  BPM 31510, an endogenous small molecule resident in mitochondria restores oxidative phosphorylation and confers re-capitulation of the BCL-2 protein family potential to induce cell death, a process that cancer evades.  Mechanistic studies show that BPM 31510 does not adversely affect normal tissue but rather optimizes the bioenergetic balance in the tumor microenvironment to "normalize" a cancer cell into behaving much like a healthy cell. 

(Logo: http://photos.prnewswire.com/prnh/20120404/CL82745LOGO )

Vikas P. Sukhatme, MD PhD, Victor J. Aresty Professor of Medicine at Harvard Medical School and Chief Academic Officer at Beth Israel Deaconess Medical Center commented, "Targeting metabolic pathways that differ between cancer cells and normal cells holds considerable promise for cancer therapy and this study falls squarely in this category. It will be instructive to see if the degree of reversal of the Warburg effect by BPM 31510 correlates with clinical outcomes." 

Results presented at ASCO in the Phase I trial on advanced, refractory, solid tumors revealed that BPM 31510 was well-tolerated with no serious side effects.  The Phase I is on-going as the MTD has not been reached to date however, there has already been very encouraging signs of efficacy with 1 patient showing a near complete response in addition to a few significant partial responses and stable disease profile in various patient cohorts. Linda Vahdat, MD, Professor of Medicine, Head, Solid Tumor Service, and Director of the Breast C
'/>"/>

SOURCE Berg Pharma
Copyright©2012 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. Study Finds Utilizing Integrated Medical and Pharmacy Data Improves Ability to Forecast Use of High-cost Specialty Treatments
2. Report Presents a Framework for Successful New Oncology Product Launches in the Pharmaceutical Sector
3. WuXi PharmaTech Files 2011 Annual Report on Form 20-F
4. Savient Pharmaceuticals to Hold First Quarter 2012 Financial Results Conference Call on Wednesday, May 9, 2012
5. Pharmaceutical Industry Service Company Awarded The UKs Most Prestigious Business Accolade in Recognition of Outstanding Achievement in International Trade
6. Academy of Managed Care Pharmacy (AMCP) Installs 2012-2013 Board of Directors
7. Auxilium Pharmaceuticals to Present at the Deutsche Bank 37th Annual Healthcare Conference
8. Simcere Pharmaceutical Group to Announce First Quarter 2012 Financial Results on Wednesday, May 9, 2012
9. Nouveau Life Pharmaceuticals (HRID) Contracts with U.S. Manufacturer to Produce New Female Supplement
10. Thomson Reuters Launches New Mobile Oncology Decision Support Solution for R&D Pharmaceutical Leaders
11. Amgen to Acquire Mustafa Nevzat, a Leading Privately Held Turkish Pharmaceutical Company
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/24/2013)... CHAPEL HILL, N.C. , May 24, 2013 ... Affairs to the forefront of many organizations, priority ... biopharmaceutical and medical device sectors understand a strong ... meeting current challenges in clinical development, market ... operate effectively to create a vital bridge between ...
(Date:5/24/2013)... -- BD (Becton, Dickinson and Company) (NYSE: BDX ), ... will present at the Deutsche Bank 38 th Annual ... a.m. (ET). A live webcast of BD,s ... www.bd.com/investors and will be available for replay through ... BD is a leading global medical technology company that ...
(Date:5/24/2013)... BEVERLY HILLS, Calif. , May 24, 2013 /PRNewswire-iReach/ ... the state,s leading non-profit substance abuse services organization, is ... at the Beverly Hills Hotel on June 6, 2013.  ... event to raise funds for the adolescent residential treatment ... as well as honor individuals whose accomplishments have positive ...
Breaking Medicine Technology:Building Medical Affairs Capabilities to Ensure Organizational Success across Key Operational Areas 2Phoenix House Honors Allergan Chairman David Pyott And Legendary Sports Agent And Humanitarian, Leigh Steinberg 2Phoenix House Honors Allergan Chairman David Pyott And Legendary Sports Agent And Humanitarian, Leigh Steinberg 3
(Date:5/24/2013)... Angeles, CA (PRWEB) May 24, 2013 ... to present the 3rd Annual EB-5 Investment Summit: Dealmakers ... The Dealmakers Conference will focus on exploring alternative finance ... the latest market, legal and economic information, and updates ... professionals within the EB-5 industry. , "Our goal ...
(Date:5/24/2013)... Stoler believes that there is much to be learned ... That’s why he hosts “Building New York—New York ... that’s why he invited Robert Glazer, Chief Executive Officer ... specialty practice in the greater New York area, whose ... sub-specialists service communities throughout New York and New Jersey ...
(Date:5/24/2013)... to the National Institutes of Health, Stevens Johnson Syndrome (SJS) ... the skin and mucous membranes. SJS occurs most commonly ... (i). In the early stages SJS presents flu-like symptoms, ... it affects the mucous membranes such as the eyes, mouth ... eye causes conjunctivitis (pink eye). Inflammation of the mouth ...
(Date:5/24/2013)... New York (PRWEB) May 24, 2013 ... Mobility® is a leading nationwide sales, installation ... for both consumer and commercial applications. The company’s ... platform lifts, vehicle lifts for mobility devices, pool ... others. 101 Mobility operates over 30 locations, primarily ...
(Date:5/24/2013)... The SunglassFIX Photo Contest lets ... while learning how to make their sunglasses, and ... only need to upload pictures of themselves, friends ... Sunglass Fix on Facebook in order to enter. ... lens replacement online store . , ...
Breaking Medicine News(10 mins):Health News:Brian Su Organizes 3rd Annual EB-5 Investment Conference in Long Beach, California 2Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 2Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 3Health News:Robert Glazer, Chief Executive Officer of ENT and Allergy Associates, LLP®, Talks About the Business of Succeeding in New York 4Health News:Personal Injury Law Firm Issues New Infographic Detailing a Potential Link Between Stevens Johnson Syndrome and Common Children’s Medicines 2Health News:Personal Injury Law Firm Issues New Infographic Detailing a Potential Link Between Stevens Johnson Syndrome and Common Children’s Medicines 3Health News:Cortec Closes Equity Transaction with 101 Mobility 2Health News:Break the Sunglass Mold – Reuse 'Em, Don’t Toss 'Em then Enter the SunglassFIX Photo Contest to Win 2
... Society for Radiation Oncology (ASTRO) will host four news briefings ... from its 51st Annual Meeting. News ... 8:00 a.m. (Central); 9:00 a.m. (Eastern) What: ... Study findings previewed:, Four months hormone therapy added ...
... While ... very few are concerned about the best method to dry their hands. This is why ... the flu, to inform the Canadian population of the undeniable advantages of paper hand towels. ... Candiac, Quebec (PRWEB) October ...
... and ST. PAUL, Minn., Oct. 29 Children,s Hospitals and ... to serve as Director of Child Health Policy and Advocacy. ... of health policy experience in Minnesota and is recognized as ... state legislature. , (Photo: http://www.newscom.com/cgi-bin/prnh/20091029/CG01324 ...
... per week can improve osteoarthritis symptoms in older patients, study ... improve that osteoarthritis in your knee? New research suggests that ... knee function better. , "Tai Chi is a mind-body ... adults with knee osteoarthritis," Dr. Chenchen Wang, co-author of a ...
... American Diabetes Wholesale ... , ... FL (PRWEB) October 29, 2009 -- American Diabetes Wholesale received the South Florida Business Journal ... The South Florida Business Journal Awards recognize health care providers and professionals in the areas ...
... determined that patients over 65 years of age with ... exercise improve physical function and experience less pain. ... martial arts that features slow, rhythmic movements to induce ... Full findings of the study are published in the ...
Cached Medicine News:Health News:Practice-changing cancer studies presented at major cancer meeting 2Health News:Cascades Launches Information Campaign on Hand Drying 2Health News:Cascades Launches Information Campaign on Hand Drying 3Health News:Children's Hospitals and Clinics of Minnesota Announces Scott Leitz as New Director of Child Health Policy and Advocacy 2Health News:Tai Chi May Help Ward Off Knee Pain in Seniors 2Health News:American Diabetes Wholesale Wins 2009 Excellence In Health Care Award from South Florida Business Journal 2Health News:Research shows Tai Chi exercise reduces knee osteoarthritis pain in the elderly 2
Sierra Wave Quickreport eliminates most dictation. Study driven functions make testing faster and easier. Complete 2/4 channel EMG/NCV/EP....
Quickly displays crisp, clear charts....
...
... 3 year warranty Set one of two ... B.I.O. exam!, One touch auto return button, ... 4 colors , Solid-State push button control ... and transformer. , Electro-Magnetic counter-balanced slit lamp ...
Medicine Products: