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Berg Pharma Companies Present Groundbreaking Approach to Understanding Autism and Identify Novel Biomarkers That May be Crucial in Diagnosis
Date:3/5/2012

SAN FRANCISCO, March 5, 2012 /PRNewswire/ -- Berg Biosystems and Berg Diagnostics, members of the Berg Pharma group of companies based in Boston, MA presented "Novel Autism Spectrum Disorder (ASD) Biomarker Discovery Using the Berg Interrogative Biology® Discovery Platform" at US-HUPO meeting in San Francisco, CA. The study was conducted by assessing tissues from families with autistic children, and in some cases where more than 1 child was afflicted by the disorder. The presentations are by Min Du, Director of Omics at Berg Diagnostics and Berg Biosystems CNS Diseases program leader, Paula P. Perez who commented, "The disorder is currently diagnosed by behavioral observation and to date no associated biomarkers have been identified and clinically validated."

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Autism is a pervasive developmental disorder with sub-groups of serious and enigmatic neuro-behavioral disorders. Autism is now considered epidemic, affecting one in 110 children in the United States today with a 4:1 male-female ratio of incidence.  "Given the nature of this disease spectrum, it is important that an understanding in the fundamental biological networks unique to autistic phenotypes are captured before any real biomarkers or therapeutics can be realized," said Niven R. Narain, President & CTO of Berg Pharma.

"These highly innovative approaches to exploring the underlying biological abnormalities of autism are revealing new genes and biochemical pathways possibly linked to the disorder," said Eric Nestler, Nash Professor and Chairman, Department of Neuroscience and Director of the Friedman Brain Institute at The Mount Sinai
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