Navigation Links
Bend Research Receives Patent for Preparing Spray-Dried Drug Dispersions Using Pressure Nozzles
Date:8/30/2010

BEND, Ore., Aug. 30 /PRNewswire/ -- Bend Research Inc. (www.bendres.com), a leading independent drug-formulation development and manufacturing company, announced today that it has received a new U.S. patent covering a process for making spray-dried solid amorphous dispersions of drugs using pressure nozzles.

The patent, which adds further protection to the company's spray-dried dispersion (SDD) technology, can be used to make solid amorphous dispersions with larger particle sizes and minimal fines (e.g., small particles). By spray-drying with a pressure nozzle, relatively large droplets are formed that dry to form dense particles with good properties for making solid dosage forms, such as tablets.

"This patent is an important addition to our spray-drying patent portfolio," said Bend Research President and CEO Rod Ray. "Customers come to Bend Research for the quality of our science, engineering, and clinical-supply manufacture, and our ability to move fast. Having patents that protect intellectual property offers them another key benefit by adding value to the formulations our scientists and engineers produce."

The patent, which is titled "Method for Making Homogeneous Spray-Dried Solid Amorphous Drug Dispersions Using Pressure Nozzles," was assigned Patent No. 7,780,988 by the U.S. Patent and Trademark Office. The inventors are Bend Research employees Ron Beyerinck, Rod Ray, Dan Dobry, and Dana Settell.

The patent covers a spray-drying process for producing solid amorphous dispersions from drugs with low aqueous solubility and polymers. In many cases, the resulting formulations increase the amount of drug that is orally absorbed when administered to a patient.

The patent addresses a common problem encountered using conventional spray-drying processes: they often produce small particles, including numerous very small particles known as "fines." As a result, solid amorphous dispersions produced using conventional processes often have poor flow characteristics and are difficult to collect efficiently and formulate into solid dosage forms. The technology covered by this patent makes it possible to produce larger particles with fewer fines, improving particle flow characteristics and collection efficiencies and simplifying downstream handling and processing.

The patent is one in a growing of number of formulation- and process-related patents associated with Bend Research's SDD technology. The SDD technology has successfully enabled the advancement of hundreds of compounds from preclinical studies to several large Phase 3 clinical trials.

About Bend Research Inc.

For more than 30 years, Bend Research has worked with clients to create value by advancing new medicines and to solve their most difficult scientific and technical problems. This success is based on the company's ability to develop, advance, and commercialize pharmaceutical technologies. The firm's innovative drug-delivery solutions grow from a solid base of scientific and engineering fundamental understanding.

Bend Research provides formulation and dosage-form support, assists in process development and optimization, manufactures clinical-trial quantities of drug candidates in its cGMP facility, and advances promising drug candidates from conception through commercialization. In addition to SDDs and other solubilization technologies such as hot-melt extrusion, Bend Research is a leader in novel formulations and controlled-release technologies.

Bend Research has more than 175 employees based in four state-of-the-art facilities in Bend, Oregon, USA.

For more information about Bend Research and its formulation and manufacturing capabilities, please contact Dana Settell via email at Dana.Settell@bendres.com or phone at 541-382-4100.


'/>"/>
SOURCE Bend Research Inc.
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. Society of Interventional Radiology Supports Research for New M.S. Treatments
2. NeoStem Comments on Recent Court Ruling Blocking the Federal Governments Funding of Embryonic Stem Cell Research
3. Embryonic Stem Cell Research in the Toilet, According to Arthritis Treatment Center
4. Preliminary Research Results Suggest up to 70% Reduction in Dose for Positron Emission Mammography Imaging
5. International Research Team Closes In On Cause of Common Form of Muscular Dystrophy
6. Reportlinker Adds Strategic Analysis of End-user Preferences in the U.S. Stem Cell Research Tools Markets
7. CVS Caremark Behavioral Change Research Partnership Presents Ongoing Research at Center for Disease Control Symposium
8. Luminex Donates Companys First MAGPIX Multiplexing System to Papua New Guinea Institute of Medical Research
9. Medco Announces Agreement to Acquire United BioSource Corporation: A Global Medical Research and Scientific Services Leader to Advance Drug Safety and Knowledge
10. New Supercomputer Connection Speeds Genetic Research
11. Sigma-Aldrich® Receives National Institutes of Health Funding for Cardiovascular Disease Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2017)... , April 20, 2017  Cogentix Medical, ... focused on providing the Urology, Uro/Gyn and Gynecology ... that Ash Keswani has joined the Company as ... this newly created position, Mr. Keswani will report ... CEO. "Our organization is delighted that ...
(Date:4/20/2017)... Research and Markets has announced ... Market Prospects: Addressing Production Complexities Through Risk Management and ... ... Pipeline and Market Prospects: Overcoming Production Complexities Through Risk ... of the current trends in the global biosimilars market, ...
(Date:4/20/2017)... 2017  CVS Pharmacy, the retail division of ... store design to enhance the retail customer experience ... products and expanded beauty selections paired with informational ... new offerings. Together with its innovative digital programs, ... customer experience at CVS Pharmacy.  ...
Breaking Medicine Technology:
(Date:4/28/2017)... ... April 28, 2017 , ... Children ... to more adverse experiences than children in the general population. That’s because foster ... neglect or other family challenges. While no fault of their own, youth who ...
(Date:4/28/2017)... ... ... People are starting to accept that hearing aids can be helpful and ... it had when great-grandpa wore his hearing aids years ago,” said Dr. Maura Marks, ... American Speaker Series (NASS) segment. “He probably wore an iPod-size hearing aid on ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... ... Manager for the North East region. Côté has 20+ years of experience within ... to Phytomer, Côté worked with an array of high-end cosmetic brands, retail brands ...
(Date:4/28/2017)... (PRWEB) , ... April 28, 2017 , ... Rob Lowe ... and now he has leant his presence to an educational purpose as the host ... one important one being cancer. In a recent episode, the series focuses on thyroid ...
(Date:4/27/2017)... ... April 27, 2017 , ... The Incentive Research Foundation is ... Nudge Guide," a groundbreaking analysis of how behavioral economics can be applied to ... to IRR programs, the report highlights proven behavioral economics approaches and the powerful ...
Breaking Medicine News(10 mins):