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Belrose Pharma Acquires Enzon's Advanced Drug Formulation Technology and Clinical Assets as Foundation for Driving Development of More Effective Injectable and Sustained Release Therapies
Date:6/19/2013

PRINCETON, N.J., June 19, 2013 /PRNewswire-iReach/ -- In its first major deal, Belrose Pharma, a new specialty pharmaceutical company dedicated to advancing development of the next generation of innovative injectable and sustained release drug therapies in patient disease populations with high unmet medical needs, today announced the acquisition of Enzon Pharmaceutical's PEGylation Linker Technology (Customized Linker Technology®) platform and associated product pipeline. Acquisition of this technology will enable Belrose Pharma to accelerate creation of improved biologic and small molecule therapies with better treatment outcomes for patients with life-threatening diseases such as breast cancer and pediatric neuroblastoma, and orphan drug diseases such as hereditary angioedema (HAE).    

Through this transaction, Belrose Pharma has added to its portfolio both "traditional" permanent PEGylation and the lesser-known releasable PEGylation technologies, as well as compounds based on both technologies. Polyethylene glycol (PEG), when permanently linked to certain compounds, has a long track record of enabling high-value commercial products through sometimes dramatic improvements in in vivo circulation, toxicity, and efficacy.  The lesser-known releasable PEGylation technique provides a different set of clinical benefits – including several targeted release options without a corresponding reduction in potency, improved drug loading, pharmacokinetics, and efficacy, and a simplified and potentially shorter clinical path to market.

"This acquisition of Enzon's permanent and releasable Customized Linker Technology® significantly strengthens our platform for accelerating the development of more patient-friendly and effective therapies in a range of specialty disease categories," said Belrose Pharma founder and CEO, Eric Gilbert. "We look forward to being a positive
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SOURCE Belrose Pharma Inc.
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