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Bayer's Xarelto® (rivaroxaban) Becomes First Fixed Dose Once-Daily Anticoagulant Tablet Approved in the UK for Stroke Prevention in non-valvular Atrial Fibrillation; and the First Single Drug Regimen for Deep Vein Thrombosis
Date:12/19/2011

provides a unique single drug solution, without the need for injections and has been shown to be effective and well-tolerated versus the dual-drug approach of heparin and warfarin. Like other similar anticoagulants (such as warfarin and heparin), rivaroxaban may cause bleeding.

"Xarelto represents a step forward in therapies to combat the consequences of blood clots which can be devastating for patients and their families," said Luis-Felipe Graterol, Medical Director at Bayer Healthcare UK. "There has been a long-established need for treatment options which don't require regular blood monitoring and avoid the potential limitations associated with both warfarin and injectable heparins."

Rivaroxaban is also indicated for the prevention of venous thromboembolism in adult patients undergoing elective hip or knee replacement surgery.

About AF

AF is the most common sustained cardiac rhythm disorder and affects approximately 750,000 people in the UK[2]. People with AF are at a five-fold increased risk for stroke, and it is a major cause of the 150,000 strokes in the UK each year[2,3]. An irregular heartbeat makes AF patients vulnerable to the formation of a blood clot in the atria, which can travel to the brain, potentially resulting in a stroke. Strokes cause damage to the brain, and can lead to physical and behavioural impairment, or even death.

About DVT

DVT is the formation of a blood clot in a deep vein that partially or totally blocks the flow of blood. In the UK, it is estimated that one in every 1,000 people are affected by venous thrombosis each year[4]. Of those, some have pre-existing risk factors including serious illness or major surgery (provoked DVT); however a number of patients will have no known pre-existing risk factors and can develop apparently spontaneous events (unprovoked DVT)[4'/>"/>

SOURCE Bayer UK
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