Navigation Links
Bayer and Onyx Begin Enrollment in STORM Trial Studying Nexavar as Adjuvant Therapy for Patients With Liver Cancer
Date:8/21/2008

WAYNE, N.J. and EMERYVILLE, Calif., Aug. 21 /PRNewswire-FirstCall/ -- Bayer HealthCare Pharmaceuticals, Inc. and Onyx Pharmaceuticals, Inc. (Nasdaq: ONXX) today announced the companies have begun enrolling patients in the STORM Sorafenib as Adjuvant Treatment in the Prevention of Recurrence of Hepatocellular Carcinoma trial. The randomized, double-blind, placebo-controlled Phase 3 study is evaluating Nexavar(R) (sorafenib) tablets as adjuvant treatment, which is treatment following surgery or local radiation, for patients with hepatocellular carcinoma (HCC), or primary liver cancer.

"Nexavar is the only systemic therapy with proven efficacy and tolerability in HCC across multiple patient populations," said Dimitris Voliotis, MD, vice president, Nexavar Clinical Development, Bayer HealthCare Pharmaceuticals. "Liver cancer is the third largest global cancer killer worldwide and there is a significant need for new therapies that can be used at all stages in the course of the disease to delay disease progression and prolong life."

In addition, the U.S. Food and Drug Administration (FDA) has completed a Special Protocol Assessment (SPA) for the STORM trial. An SPA is a written agreement on the design and size of a clinical trial intended to form the basis for a new drug application.

Phase 3 Trial Design

The international multicenter study is expected to enroll approximately 1,100 patients and will include patients who have received surgical resection or local ablation. The study will look at whether providing oral Nexavar in the adjuvant setting delays the time to recurrence and increases overall survival. The primary endpoint of the study is recurrence free survival. Secondary endpoints include overall survival, ti
'/>"/>

SOURCE Onyx Pharmaceuticals, Inc.; Bayer HealthCarePharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Cell Therapeutics, Inc. (CTI) to Hold Conference Call to Discuss Agreement With Bayer Schering Pharma for Access to Phase III Zevalin(R) FIT Trial Data
2. Bayer HealthCare Celebrates 20th Anniversary of Kogenate(R) Product Line and 8 Billion IU Milestone at 2008 WFH World Congress
3. Bayer and Regeneron Dose First Patient in Second Phase 3 Study for VEGF Trap-Eye in Wet Age-Related Macular Degeneration
4. Bayer Issues Additional Guidance to Physicians on Trasylol(R)
5. Genzyme and Bayer Schering Pharma AG, Germany Announce Start of Phase 3 Program with Alemtuzumab for Treatment of Multiple Sclerosis
6. Genzyme and Isis Begin Second Phase 3 Trial Of Mipomersen
7. Light Sciences Oncology Begins Clinical Trials of Litx Therapy in Patients with Enlarged Prostate
8. Catalyst Pharmaceutical Partners, Inc. Begins Enrollment for U.S. Phase II Clinical Trial of CPP-109 in Patients with Methamphetamine Addiction
9. Micromet and Nycomed Begin Formal Preclinical Safety Studies for Antibody MT203 for Inflammatory and Autoimmune Diseases
10. Champions Biotechnology Begins Preclinical Development of Its Lead Oncology Drug Candidate
11. European Enrollment Begins in Pivotal Phase 3 Trial of Novel Combination Medicine Developed by Cogentus Pharmaceuticals
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/27/2015)... Vein & Surgery Clinic is the only clinic offering laser ... Victoria, Texas . The clinic specializes in the ... for a variety of medical and cosmetic conditions. High-end vein ... for their patients. Since adding laser tattoo removal, Victoria Vein ... residents get rid of their unwanted ink. "Our ...
(Date:3/27/2015)... 27, 2015   Cypher Genomics, Inc., ... data showing that, compared to a panel of ... highly equivalent interpretations of whether certain genetic abnormalities ... in a fraction of the time. Cypher,s Mantis ... comprehensive genetic analysis in non-invasive prenatal testing (NIPT) ...
(Date:3/27/2015)... Holdings, Inc. (NYSE and SIX: ZMH) is celebrating a key milestone in ... Knee System. ,   ... introduced the NexGen knee system, with its innovative design and ... of the NexGen knee have taken place worldwide. ... the importance of design innovation and component quality for surgeons and patients ...
Breaking Medicine Technology:Victoria Vein And Surgery Clinic Uses Advanced Astanza Duality Tattoo Removal Technology 2New Data at ACMG Shows Cypher's Software Can Automate Interpretation of Genetic Variants to Advance Non-invasive Prenatal Testing 2New Data at ACMG Shows Cypher's Software Can Automate Interpretation of Genetic Variants to Advance Non-invasive Prenatal Testing 3Zimmer Celebrates Key Milestones For NexGen Complete Knee System 2
... As obesity rates and the cost of healthcare continue ... in Washington D.C. is bringing together industry thought leaders, ... address pressing public health issues utilizing mobile health technology. ... wearable body monitoring systems, recently announced the findings from ...
... 9, 2010 HeartWare International, Inc. (Nasdaq: ... invasive, miniaturized circulatory support technologies that are revolutionizing the ... Aaronson, MD, MS, will present data from the ADVANCE ... American Heart Association (AHA) Scientific Sessions 2010 at McCormick ...
Cached Medicine Technology:Results of Two New Clinical Studies Show Promise of Emerging Mobile Health Technology to Combat Obesity Epidemic 2Results of Two New Clinical Studies Show Promise of Emerging Mobile Health Technology to Combat Obesity Epidemic 3HeartWare Bridge-to-Transplant Data Featured as Late Breaking Clinical Trial at American Heart Association Scientific Sessions 2010 2
(Date:3/27/2015)... 2015 Wellness for Cancer–the first organization ... for the spa and wellness industry–has certified Hands On ... experienced or are living with cancer. Hands On ... Network, will be identified with a special Wellness for ... of safe, therapeutic services for cancer patients. , Wellness ...
(Date:3/27/2015)... In her mid-forties and with a lifelong speech ... K. arrived at JET Uniform & Supply for ... scared. The owners and staff at JET, which had partnered ... offer jobs to challenged residents like Monica, were patient. ... begin with the end in mind,” says Stephen Milaney, co-owner ...
(Date:3/27/2015)... March 27, 2015 Florida Hospital is excited ... the team’s exclusive health care provider for the 2015 and ... Hospital provides medical care and an athletic trainer for the ... kick off its season against the Cleveland Gladiators at Amalie ... partnership is extremely important to us as it gives us ...
(Date:3/27/2015)... New York (PRWEB) March 27, 2015 ... http://www.lipitorlawsuitcenter.com/ ) that allege the statin medication increases the ... has granted Pfizer Inc.’s Motion to Dismiss four individual ... to a Case Management Order issued in the U.S. ... the Court determined that the dismissals were warranted because ...
(Date:3/27/2015)... First Choice Emergency Room opened its new Summerwood ... W Lake Houston Pkwy, Houston, Texas and is open 24-7. ... to delivering the highest quality emergency medical care to my ... Choice Emergency Room Summerwood. , To celebrate the ... Creek High School at First Choice Emergency Room’s ribbon cutting ...
Breaking Medicine News(10 mins):Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Certified as “Cancer Aware” by Wellness for Cancer and Recognized on Spafinder.com 2Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Certified as “Cancer Aware” by Wellness for Cancer and Recognized on Spafinder.com 3Health News:Hands On HealthCare Massage Therapy & Wellness Day Spa Certified as “Cancer Aware” by Wellness for Cancer and Recognized on Spafinder.com 4Health News:Red Deer Uniforms Shop Celebrates 3rd Year Sewing Hope for the Challenged 2Health News:Red Deer Uniforms Shop Celebrates 3rd Year Sewing Hope for the Challenged 3Health News:Florida Hospital Is Kicking off the 2015 Season as the Exclusive Health Care Provider for the Tampa Bay Storm 2Health News:Florida Hospital Is Kicking off the 2015 Season as the Exclusive Health Care Provider for the Tampa Bay Storm 3Health News:Lipitor Lawsuits Move Forward in Federal Multidistrict Litigation, as Court Rules on Pfizer’s Motion to Dismiss Certain Cases 2Health News:Lipitor Lawsuits Move Forward in Federal Multidistrict Litigation, as Court Rules on Pfizer’s Motion to Dismiss Certain Cases 3Health News:First Choice Emergency Room Opens New Facility in Houston, Texas 2
... the world , including India, must face the challenges ... all their citizens get access to effective healthcare // ... catastrophic medical expenses, a new World Bank report said. ... struggling to cope with sharply rising costs even while ...
... Ashok Bhatt, Gujarat Health minister was admitted to UN Mehta’s civil hospital on Thursday morning. Hospital authorities said, he was ... ... ... ...
... jobs on the NHS worsened today after Oxford Radcliffe Hospitals said ... budget.// The Trust operates four hospitals in Oxford and Banbury. ... although it currently has 600 vacancies. Campaign group Health Emergency said ... health sector and this number could only double by the end ...
... persons, including the Managing Director of a pharmaceutical ... of Ephedrine tablets, a controlled substance notified under ... 1985. ,According to Directorate of Revenue ... remanded to judicial custody by the Metropolitan Sessions ...
... are not comfortable talking on HIV/AIDS and sexual and ... the city's adolescents have problems related to sex, according ... as 50 per cent adolescents studying from classes IX ... at least comes emotional disturbances and social adjustment with ...
... to a Norwegian research it was found that Invitro ... pregnancy. According to the statistics it is found// that ... in women who have IFV. Placenta praevia is the ... this the placenta covers part or the entire cervix, ...
Cached Medicine News:
For the quantitative determination of alkaline phosphatase in human serum....
Auto LDL-Cholesterol, automated analyzer test kits....
Storage temperature: 15 - 30C, linearity: 0 - 20 mg/dL, expected value: male: 3.0 - 7.0 mg/dL and female: 2.2 - 6.2 mg/dL. Available with calibrator and number of tests 125....
For the quantitative determination of Uric Acid in serum. Linearity: 25 mg/dl....
Medicine Products: