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Bayer Announces Leukine(R) Data Presentations at 45th American Society of Clinical Oncology (ASCO) Annual Meeting
Date:5/29/2009

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Neuroblastoma

  • A phase III randomized trial of the chimeric anti-GD2 antibody ch14.18 with GM-CSF and IL2 as immunotherapy following dose intensive chemotherapy for high-risk neuroblastoma: Children's Oncology Group (COG) study ANBL0032
    • Lead investigator: A. L. Yu, Children's Oncology Group
    • Abstract 10067z, Oral Presentation, Tuesday, June 2, 8:00 AM to 10:45 AM, Level 3, W304E

About Leukine(R)

Leukine(R) (sargramostim) is the only growth factor approved in the U.S. for use following induction chemotherapy in older adults (older than 55) with acute myelogenous leukemia (AML) to shorten the time to neutrophil recovery and reduce the incidence of severe and life-threatening infections and infections resulting in death. Leukine also has been approved in the U.S. for use in four additional indications: myeloid reconstitution following allogeneic and autologous bone marrow transplantation (BMT), peripheral blood stem cell (PBSC) mobilization and subsequent myeloid reconstitution in patients undergoing PBSC transplantation and bone marrow transplantation failure or engraftment delay. Leukine is available in two formulations, both of which are suitable for IV infusion and subcutaneous injection:

  • Liquid: 500 mcg/mL sterile solution in multi-use vial
  • Lyophilized powder: 250 mcg in single-use vial ready for sterile reconstitution

Among its indications, Leukine is the only myeloid growth factor approved to reduce the incidence of infections resulting in early death following induction chemotherapy in older adults with AML.

Important Safety Considerations

Leukine is contraindicated in patients with excessive
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SOURCE Bayer Healthcare Pharmaceuticals Inc.
Copyright©2009 PR Newswire.
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