Navigation Links
Basic Science Discoveries Yield Progress in Hepatology
Date:4/25/2008

Advances in Virology Translate Into New Promising Drugs to Combat Hepatitis

C

Clarification of Oncogenic Pathways Aids Liver Cancer Research

Stem Cells of Potential Benefit in Liver Transplantation

MILAN, April 26 /PRNewswire/ --

- Systems Biology Helps to Solve Complex Liver Diseases

At today's sessions of the 43rd Annual Meeting of the European Association for the Study of the Liver (EASL), experts reported advances in basic research that have important implications for the eventual treatment of people with chronic liver diseases.

The goal of basic or "fundamental" biomedical science is to gain knowledge and understanding for its own sake, without reference to a particular practical problem. "Translational" science transforms basic knowledge into practical terms. "Applied" research, such as "clinical trials," takes the discoveries of basic research even further and uses them to solve specific, clearly defined medical problems. Basic, translational, and applied research are each necessary to progress in medicine, including Hepatology.

In virology, for example, notable progress has been made in clarifying the structure of the Hepatitis C virus (HCV), leading to the development of new experimental drugs such as protease inhibitors and polymerase inhibitors, drugs that inhibit virus production. Some of these drugs have been extensively tested and some are currently in phase II trials. Based on results to date, it is clear that these drugs can be highly effective in combination with pegylated Interferon and Ribavirin. Phase III trials are planned.

Important basic science advances in genetics and systems biology have also been reported, offering potential progress for strategies to treat hepatocellular carcinoma (HCC). Using genomics and microarrays to determine gene expression, scientists have discovered that there are different biological pathways - called "oncogen
'/>"/>

SOURCE EASL - European Association for the Study of the Liver
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Kibow Biotech Obtains Australian, Chinese and Indian Patents Protecting the Composition and Basic Technology Behind Its Oral Probiotic Formulation for Chronic Kidney Failure
2. Human Genome Sciences Completes Enrollment in First of Two Phase 3 Lymphostat-B(R) Trials
3. Edwards Lifesciences Announces First Implants in U.S. Study of Minimally-Invasive Pulmonic Valve
4. Ardea Biosciences Presents Data Demonstrating Favorable Pharmacokinetics and Efficacy for Mitogen-Activated ERK Kinase (MEK) Inhibitors
5. Sangamo BioSciences Announces Presentation of Data on ZFP Therapeutic for Glioblastoma at American Association for Cancer Research (AACR) Meeting
6. HUYA Bioscience Intl Announces First Pre-IND Outcome for a Development Stage Compound Sourced From China - HBI-8000, Promising New Cancer Compound
7. BiPar Sciences Expands Clinical Program for BSI-201, a Novel DNA Repair Inhibitor, in Brain Cancer
8. ALS Therapy Development Institute Signs Collaboration Agreement with the Allen Institute for Brain Science
9. Parion Sciences Announces Phase I Clinical Results for Novel Dry Mouth Treatment
10. Monogram Biosciences Provides Progenics Pharmaceuticals with HIV Assays for Use in Clinical Trials
11. Genaera Corporation Announces MSI-1436 Data Presented at Society of Neuroscience Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... 2014  Zafgen, Inc., a leading biopharmaceutical company dedicated ... patients, today announced initial results from its Phase ... methionine aminopeptidase 2 (MetAP2), in patients with Prader-Willi ...  These results showed improvements in body weight, hunger-related ...
(Date:1/14/2014)... Mass. , Jan. 14, 2014 HeartWare ... leading innovator of less invasive, miniaturized circulatory support technologies ... today announced that it expects revenues for the fourth ... expected full-year 2013 revenues to approximately $208 million. ...
(Date:1/14/2014)... Jan. 14, 2014 InformEx, North America,s ... high-value chemistry, will hold the 30 th edition of ... Convention Center from January 21-24. (Logo: ... top pharmaceutical, fine chemical and specialty chemical companies will take ...
Breaking Medicine Technology:Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 2Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 3Zafgen Announces Initial Results from Phase 2a Study of Beloranib in Patients with Prader-Willi Syndrome 4HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 2HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 3HeartWare International Announces Preliminary Fourth Quarter 2013 Revenues 4Media Advisory: InformEx 2014 Events & Speaker Lineup for 30th Edition Conference in Miami Beach 2
... , one of the nation,s largest institutional pharmacy ... as its new senior vice president of sales ... position, Gauff will be responsible for leading a ... Remedi,s innovative offerings, including the continued roll-out of ...
... CareFusion today launched the Nicolet™ EEG (Electroencephalography) ... wave data used for the diagnosis and treatment ... http://photos.prnewswire.com/prnh/20100706/CAREFUSIONLOGO ) The Nicolet EEG ... into a single, portable unit for pediatrics and adults ...
Cached Medicine Technology:Remedi SeniorCare® Appoints Corey Gauff SVP of Sales and Account Management 2CareFusion Launches Wireless Diagnostic and Monitoring Neurological Device 2
(Date:7/9/2014)... July 10, 2014 For the first time, researchers ... Aboriginal population in Canada uses health care. A new ... to clearly demonstrate the unique challenges faced by urban ... St. Michael,s Hospital. , The findings, published today ... urban First Nations individuals and the general population. , ...
(Date:7/9/2014)... was told she had an aneurysm, she figured an invasive ... "I was devastated," said Wakulich, who is 56 years old ... a serious diagnosis. Then I met Dr. Bernard Bendok who ... invasive procedure. It was something I didn,t even know was ... U.S. clinical trial to evaluate the safety and effectiveness of ...
(Date:7/9/2014)... cancer, researchers have uncovered mutations in a cell-signaling pathway ... knowledge may expand treatments for patients because drugs targeting ... are in clinical trials. , Reporting July 9 in ... (TCGA), including researchers at Washington University School of Medicine ... studied tumors from 230 patients with lung adenocarcinoma. , ...
(Date:7/9/2014)... found that fecal transplantation is effective and safe for ... is the result of a study led by Colleen ... Gastrointestinal Medicine at The Women,s Medicine Collaborative. The study ... of print in the American Journal of Gastroenterology ... diff , has increased to epidemic proportions over the ...
(Date:7/9/2014)... are personal and subjective, the human brain turns ... emotions across different senses, situations and even people, ... Adam Anderson. , "We discovered that fine-grained patterns ... area of the brain associated with emotional processing, ... individual,s subjective feeling," says Anderson, associate professor of ...
Breaking Medicine News(10 mins):Health News:Urban Aboriginal people face unique health challenges 2Health News:New type of stent could help some brain aneurysm patients 2Health News:Lung cancer study hints at new treatments 2Health News:Women's Medicine Collaborative examines safety of fecal transplant to treat C. difficile 2Health News:Study cracks how the brain processes emotions 2
... bleary- eyed Britons, relief from hay fever may soon ... designed to prevent// allergic reactions like a running nose, itching eyes, ... vaccine pill contains small amounts of Timothy grass pollen; main allergens ... before hay fever season. ,This pill follows the hay ...
... at Cornell University in Ithaca and Weill Cornell Medical ... of 23 protein biomarkers// in cerebrospinal fluid that acts ... to identify patients living with Alzheimer’s disease. ... of the journal Annals of Neurology. ,Right ...
... for under-14 is being conducted at the Auckland Aquatic Center ... participating in a game at the West Wave Aquatic Centre ... problems and had to be admitted in the hospital. ... The council is deeply concerned by what had occurred and ...
... by the Canadian Food Inspection Agency to the public asking them ... fear that it may be contaminated with salmonella. ,This ... 0 33383 65201 6 and Dec. 7. as the best before ... shops but the agency fears some people may still have it ...
... zonal hospital found themselves in peril after doctors and ... The resignation en masse was submitted on Sunday, citing ... doctors – said senior physician Dr Gaurang Mishra. ... Dr. Raj Kumar Mahoto were beaten up by the ...
... For smokers, it ‘s bad news again. The Queensland (Australia) ... ,Smoking will soon be prohibited in cars carrying ... finding that one child under five years of age, dies ... ,The Queensland Health Minister while unveiling the Health of Queenslanders ...
Cached Medicine News:Health News:Revolutionary Pill Promises Relief for Hay Fever Sufferers 2Health News:Protein ‘Fingerprint’ in Spinal Fluid Could Spot Alzheimer’s Dise 2Health News:Protein ‘Fingerprint’ in Spinal Fluid Could Spot Alzheimer’s Dise 3
... The Sysmex pocH-100i is the first Sysmex ... low daily testing requirements. With its small ... differential from just 15 L of whole ... any small healthcare site including the emergency ...
... a self-contained, compact, easy-to-use, bedside automated cell ... Ichor system provides a hematology profile of ... platelet aggregation within five minutes. The test ... is added to both an EDTA baseline ...
... pacemaker family, which includes the world's ... the most advanced pacemaker technology available, ... the first and only U.S. commercially ... fibrillation (AF). The AF Suppression algorithm ...
... catheters that are controlled by an ... console processes the refrigerant, which when ... the catheter, creates cryogenic temperatures., ,The ... touch-screen interface. From this interface, the ...
Medicine Products: