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Bad News to Bad Bugs: Northern Antibiotics Develops Novel Polymyxins With Reduced Toxicity
Date:7/1/2008

aara, CEO and co-founder of Northern Antibiotics Ltd.

"The need for well-tolerated antibiotics that are active against multidrug-resistant Gram-negative bacteria is urgent. Enteric bacteria are responsible for more than 80% of all the hospital infections caused by Gram-negative bacteria, and now they are rapidly becoming resistant to most antibiotics that are currently used to treat them. Plasmid-mediated carbapenemases, probably transferred from Klebsiella pneumoniae, have now been found in E. coli, the clinically most important species of Gram-negative enteric bacteria. Also plasmid-mediated methylases that cause resistance to all aminoglycosides have been encountered. Finally and quite alarmingly, a single genetic element conferring transferable resistance to carbapenems, aminoglycosides and fluoroquinolones has been reported in K. pneumoniae. One does not need to be very smart to guess what follows when these plasmids become more common and the resulting extremely multidrug-resistant strains start to spread."

About Northern Antibiotics Ltd.

Founded in 2003 and headquartered in Helsinki, Finland, Northern Antibiotics Ltd is engaged in the discovery and development of novel antibiotics against multidrug-resistant Gram-negative bacteria. For more information, visit http://www.northernantibiotics.com.

Contact:

Dr. Barry Mason

Business Development Consultant

Email: barry.mason@northernantibiotics.com

Phone: +44(0)1625-858396

Mobile: +44(0)7713-261356


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SOURCE Northern Antibiotics Ltd
Copyright©2008 PR Newswire.
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