Navigation Links
BHR Pharma Announces Phase 3 SyNAPSe Study of Progesterone as a Neuroprotective Agent for Traumatic Brain Injury
Date:9/8/2009

HERNDON, Va., Sept. 8 /PRNewswire/ -- BHR Pharma, LLC (BHR) announced today that it will initiate a global, Phase 3, multi-center pivotal trial (www.synapse-trial.com) to evaluate the effectiveness of its proprietary BHR-100 intravenous progesterone infusion product as a neuroprotective agent for treating severe traumatic brain injury (TBI) patients in early 2010.

BHR will enroll approximately 1,200 patients with severe (Glasgow Coma Scale scores of 4-8), closed-head trauma TBI at 100-120 medical centers in the United States, Europe, Israel and additional countries.

Randomized patients will receive a five-day (120-hour) intravenous infusion of progesterone or placebo. Unlike intravenous progesterone infusions described in the medical literature, BHR-100 is a ready-to-use infusion designed to meet all U.S. Food and Drug Administration approval requirements.

BHR is collaborating with the American Brain Injury Consortium (ABIC) and the European Brain Injury Consortium (EBIC) to identify the trial sites and help design the clinical study. PRA International is the Contract Research Organization for the trial.

TBI is a non-degenerative, non-congenital insult to the brain from an external mechanical force, possibly leading to permanent or temporary impairments of cognitive, physical and psychosocial functions with an associated diminished or altered state of consciousness.

Approximately 1.5 million Americans per year suffer a traumatic brain injury, resulting in 50,000 deaths, 235,000 hospitalizations and 80,000 cases of long-term disability. Incidence of TBI in all industrialized countries is comparable to that in the U.S., with estimates ranging from 150 to more th
'/>"/>

SOURCE BHR Pharma, LLC
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. DOR BioPharma Announces NIH Grant Award to Support Phase 1/2 Clinical Trial of DOR201 in Radiation Enteritis
2. LigoCyte Pharmaceuticals Initiates a Randomized, Double Blind, Placebo Controlled Norovirus Vaccine Study Including Live Virus Challenge
3. Vion Pharmaceuticals Announces Results of the Oncologic Drugs Advisory Committee Meeting for Onrigin(TM)
4. Nitec Pharma Reports Positive and Highly Significant Phase III Results From Capra-2 Study of Lodotra(TM) in RA
5. Sagent Pharmaceuticals Announces Launch of Adenosine Injection, USP, in 6 mg per 2 mL Single-Dose Vials
6. Head of Process Sciences at aTyr Pharma to Speak at Bio Korea 2009
7. Octapharma Targeting the Major Risk of Hemophilia Treatment - FVIII Antibodies
8. ISTA Pharmaceuticals Announces Positive Preliminary Phase 3 Clinical Results to Support sNDA Filing for Once-Daily Xibrom(TM) 0.09%
9. Research-Based Biopharmaceutical Company Awards Trials to DATATRAK
10. NovaBay Pharmaceuticals to Present New Data on Lead Anti-Infective Compound at the 2009 ICAAC Annual Meeting
11. Impax Pharmaceuticals Selects OmniComm Systems to Provide eClinical Solutions for International Phase III Study in Parkinsons Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Pharmaceuticals International, Inc. (NYSE: VRX and ... the Hart-Scott-Rodino Antitrust Improvements Act of 1976 ("HSR") with ... indirect wholly-owned subsidiary, Sapphire Subsidiary Corp. ("Purchaser"), for all ... Medical, Inc. (NASDAQ: SLTM ) ("Solta") at ...
(Date:1/15/2014)... NEW YORK , Jan. 15, ... new market research report is available ... Global Markets and Technologies for ... on Routes of Administration ...
(Date:1/15/2014)... 2014  A novel wearable injector slightly larger than an Oreo ... to self-inject prescription drugs in the large doses required to ... autoimmune deficiencies, and genetic disorders.  An emerging ... 2018, according to analysts.   Many of these drugs will require ...
Breaking Medicine Technology:Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 2Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 3Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 4Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 5Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 6Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 7Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 8Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 9Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 10Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 11Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 12Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 13Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 14Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 15Global Markets and Technologies for Advanced Drug Delivery Systems -- Focus on Routes of Administration 16Enable Injections Presents A New Class of Injectors for Drug Delivery at PEPTalk, Drug Delivery Partnership Meetings 2
... 2012  ConvaTec, a world-leading developer and marketer of ... today announced that Amcare Ltd, a wholly-owned subsidiary ... Healthcare Holdings Ltd and subsidiaries ("SureCalm Healthcare"), a ... home delivery of prescribable stoma care and continence ...
... Clinical informatics may hold the key to better population ... in the United States if health organizations can ... health.  A new PwC US Health Research Institute (HRI) ... clinical informatics – the integration of information technology ...
Cached Medicine Technology:ConvaTec Announces Acquisition of SureCalm Healthcare 2Health Organizations Count on Clinical Informatics to Improve Patient Health and Reduce Healthcare Costs, Finds PwC Report on Clinical Informatics in Healthcare 2Health Organizations Count on Clinical Informatics to Improve Patient Health and Reduce Healthcare Costs, Finds PwC Report on Clinical Informatics in Healthcare 3Health Organizations Count on Clinical Informatics to Improve Patient Health and Reduce Healthcare Costs, Finds PwC Report on Clinical Informatics in Healthcare 4Health Organizations Count on Clinical Informatics to Improve Patient Health and Reduce Healthcare Costs, Finds PwC Report on Clinical Informatics in Healthcare 5Health Organizations Count on Clinical Informatics to Improve Patient Health and Reduce Healthcare Costs, Finds PwC Report on Clinical Informatics in Healthcare 6
(Date:4/18/2014)... A discovery by Northwestern Medicine scientists could lead to ... scarring in people with scleroderma. , Fibrosis, or ... tightening of the skin and lungs can lead to ... The concept for new therapeutic options centers on findings ... Medicine-Rheumatology, who identified the role that a specific protein ...
(Date:4/17/2014)... popular vaccine brands for children may not be the ... cost factors when choosing vaccines, driving the market toward ... a new study by University of Illinois researchers. , ... by numerous factors," says Sheldon H. Jacobson, a co-author ... and of mathematics at the U. of I. "In ...
(Date:4/17/2014)... in the April issue of Immunity , Kevin ... Medical Research, says it,s time to take a fresh ... sepsis, which kills millions worldwide every year, including ... released into the bloodstream to fight an injury or ... for maintaining good health without inflammation, wounds and ...
(Date:4/17/2014)... older Americans suffer from depression, often brought on by ... a project that followed the lives of thousands ... that Internet use among the elderly can reduce the ... "That,s a very strong effect," said Shelia Cotten, a ... media who led the project. "And it all has ...
(Date:4/17/2014)... 2014 EcoHealth Alliance, a nonprofit organization that focuses ... comprehensive review today examining the current state of knowledge ... calls for improved global surveillance strategies to combat the ... of Ebola in West Africa that has claimed the ... and Liberia. According to the World Health Organization ...
Breaking Medicine News(10 mins):Health News:New clues on tissue scarring in scleroderma 2Health News:Study recalculates costs of combination vaccines 2Health News:Feinstein Institute researcher publishes new perspective on sepsis 2Health News:Internet use can help ward off depression among elderly 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 2Health News:Re-emergence of Ebola focuses need for global surveillance strategies 3
... Dr. Joan T. Merrill, Wednesday, May 28, 2008 ... at http://www.lupus.org , WASHINGTON, May 23 ... live moderated chats, featuring the,nation,s leading experts in lupus. ... their families to ask questions and learn more,about lupus ...
... cut need for 2nd treatment , , FRIDAY, May ... satisfaction and low rates of re-surgery were found ... had minimally invasive laparoscopic fundoplication (anti-reflux surgery) performed ... , Studies have shown the short-term effectiveness ...
... ultrasound technique to spot areas of blood flow in ... unnecessary biopsies, according to a new study by urologists ... the Kimmel Cancer Center at Jefferson in Philadelphia. The ... blood flow in the prostate were twice as likely ...
... Ala., May 23 With the anticipated opening,of a ... be renamed,the Benjamin Russell Hospital for Children. The announcement ... a major capital campaign in support of the,pediatric medical ... have pledged $25 million in support of,Children,s Hospital. The ...
... 23 The PA Access to Basic,Care plan ... insurance,for their employees, Department of Community and Economic ... awards luncheon in,Pittsburgh today., "The vast majority ... are employed by small businesses that struggle to ...
... Hospital of Atlanta,Inc. engaged in a systematic scheme to ... Page Perry, LLC law firm, which,filed suit against the ... of patients overbilled by the practice., Former Saint ... a carotid artery stent procedure he underwent in 2005 ...
Cached Medicine News:Health News:Lupus Live Web Chat Focuses on Medication Management 2Health News:Patients Pleased With Laparoscopic GERD Surgery 2Health News:Monitoring blood flow helps improve prostate biopsies, Jefferson researchers report 2Health News:Children's Hospital Campus to be Renamed Thanks to Transformational Capital Gift 2Health News:Children's Hospital Campus to be Renamed Thanks to Transformational Capital Gift 3Health News:Children's Hospital Campus to be Renamed Thanks to Transformational Capital Gift 4Health News:PA ABC Will Benefit Commonwealth's Small Businesses, DCED Secretary Says 2Health News:Saint Joseph's Hospital of Atlanta Sued Over Patient Admission and Billing Scheme, According to Page Perry, LLC 2
... a electronic medical records software for healthcare ... Medical Office Records does more than just ... to follow the flow of your patient ... encounters to establishing new examination records via ...
... The eCHARMS suite comprises the ... 2000 product line. Currently, there ... signature & enterprise-wide disclosure reporting. ... new HIM management tool. These ...
... Electronic Medical Office (EMO) truly built for ... unique needs of your practice. The ChartLogic™ ... record system (EMR, EHR, and EPR), and ... new level of efficiency and performance. In ...
... serving the needs of orthopaedic practices ... a better orthopaedic practice, an orthopaedic ... EMR software has been intuitively developed ... country resulting in a complete workflow ...
Medicine Products: