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BD Rx Announces FDA Approval of High-Demand Injectable for Pain Management

ce the potential risk of medication error and allowing for more focus on the patient and less on injection preparation. Clinicians perform up to 20 steps in a traditional vial and syringe injection sequence. BD Simplist prefilled injectables reduce the injection sequence to approximately 12 steps.

About Morphine Sulfate Injection, USP

Morphine sulfate is an opioid agonist indicated for the management of pain not responsive to nonnarcotic analgesics.


Morphine sulfate is contraindicated in:

  • patients with known hypersensitivity to morphine
  • patients with respiratory depression in the absence of resuscitative equipment
  • patients with acute or severe bronchial asthma or hypercarbia
  • any patient who has or is suspected of having paralytic ileus

Risk of Medication Errors
It is important to take care when prescribing and administering the injection to avoid dosing errors due to confusion between different concentrations and between mg and mL, which could result in accidental overdose and death.

Cardiovascular Instability
While low doses of intravenously administered morphine have little effect on cardiovascular stability, high doses are excitory, resulting from sympathetic hyperactivity and increase in circulatory catecholamines. Have Naloxone Injection and resuscitative equipment immediately available for use in case of life-threatening or intolerable side effects and whenever morphine therapy is being initiated.

Respiratory Depression
Respiratory depression is the primary risk of Morphine Sulfate Injection USP.  Respiratory depression occurs more frequently in elderly or debilitated patients and in those suffering from conditions accompanied by hypoxia, hypercapnia or upper airway obstruction, in whom even moderate therapeutic doses may

SOURCE BD (Becton, Dickinson and Company)
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