Navigation Links
BCMA Targeted Therapies, 2017-2030: Even Though Big Pharmaceutical Companies Dominate the Current Space, Several Start-Ups/Small Companies Have Emerged - Research and Markets

DUBLIN, Apr. 13, 2017 /PRNewswire/ --

Research and Markets has announced the addition of the "BCMA Targeted Therapies, 2017-2030" report to their offering.

The "BCMA Targeted Therapies, 2017-2030" report features an extensive study on the current market landscape of B-cell maturation antigen (BCMA) targeted therapies and offers a comprehensive discussion on the future potential of this market. With no commercial products, the market is still in its infancy.However, industry experts have pinned significant hopes on the novel technologies being developed by start-ups/small companies and the research being conducted at academic institutes.

B-cell maturation antigen (BCMA), an important biomarker of the B-cells, has emerged as a promising therapeutic target for the treatment of multiple myeloma and other hematological malignancies. The antigen is universally expressed on the surface of multiple myeloma cells. The research focus shifted towards BCMA targeted therapies in 2004, when the role of BCMA was first indicated in the progression of multiple myeloma. It is the second most common type (13%) of all hematological malignancies.

Results of preclinical and clinical studies have demonstrated the potential benefits of this class of therapies; the major highlight being their attractive safety profile. As more molecules undergo clinical validation and eventually get commercialized, we believe the overall interest will continue to rise. In fact, our promising outlook is backed by a strong belief that this novel class of therapies is likely to cater to the current unmet need where the existing treatment modalities are not efficient. The upside could be higher; however, it depends on a favorable market environment, reimbursement practices and regulatory regimes.

The prime target indication of these novel molecules is B-cell malignancies, specifically multiple myeloma. BCMA-specific therapies are anticipated to emerge as viable treatment options for such indications. Post initial research on such therapies, many players have entered into collaborations with other stakeholders to fund the clinical and commercial development of their products. Some clinical stage products that have emerged out of such collaborations include bb2121 (bluebird bio/Celgene) and BCMA-CART (Novartis/Abramson Cancer Center of the University of Pennsylvania).

The pipeline currently comprises of 23 molecules that are under development for the treatment of a variety of B-cell malignancies. One of the key objectives of this report was to understand the evolution of the current market and to quantify the opportunities laid down by the innovative BCMA targeted programs of both small and big pharma companies.

Key Topics Covered:

1.1. Chapter Overview
1.2. Research Methodology
1.3. Chapter Outlines


3.1. Chapter Overview
3.2. The B-Cell Maturation Antigen
3.3. Drug Classes for BCMA Targeted Therapies
3.4. BCMA Targeted Therapies and Research Landscape
3.5. Emergence of BCMA as a Therapeutic Target for the Treatment of Multiple Myeloma
3.6. BCMA Related Targets: A Case Study

4.1. Chapter Overview
4.2. Development Pipeline
4.3. Distribution by Phase of Development
4.4. Distribution by Type of Molecule
4.5. Distribution by Type of Developer
4.6. Distribution by Indication
4.7. Geographical Landscape
4.8. Developer Landscape

5.1. Chapter Overview
5.2. bb2121 (bluebird bio, Celgene)
5.3. CART-BCMA (Novartis, Abramson Cancer Center of the University of Pennsylvania)
5.4. Anti-BCMA CAR-T (National Cancer Institute)
5.5. Anti-BCMA CAR-T (Southwest Hospital, China)
5.6. GSK2857916/J6M0-mcMMAF (GSK, Seattle Genetics)
5.7. AMG 420/BI 836909 (Amgen, Boehringer Ingelheim)
5.8. BCMA Targeted Therapies: Clinical Development Analysis

6.1. Chapter Overview
6.2. BCMA Targeted Therapies: List of Funding Instances
6.3. Funding Instances: Distribution by Year
6.4. Funding Instances: Distribution by Type of Model
6.5. Leading Players: Distribution by Number of Funding Instances
6.6. Most Active Venture Capital Firms/Investors

7.1. Chapter Overview
7.2. Partnership Models/Agreements
7.3. BCMA Targeted Therapies: Recent Collaborations
7.4. Recent Collaborations: Distribution by Year
7.5. Recent Collaborations: Distribution by Type of Model
7.6. Recent Collaborations: Distribution by Type of Molecule
7.7. Recent Collaborations: Most Active Companies

8.1. Chapter Overview
8.2. Scope and Limitation
8.3. Forecast Methodology
8.4. Overall BCMA Targeted Therapeutics Market
8.5. BCMA Targeted Therapeutics Market: Drug Specific Forecasts

9.1. BCMA has Emerged as a Potential Antigen for the Treatment of Multiple Myeloma
9.2. Led by a Number of Technological Advances, CAR- T Therapies are the Current Flag-Bearer
9.3. Even Though Big Pharmaceutical Companies Dominate the Current Space, Several Start-Ups/Small Companies Have Emerged
9.4. Growing Partnerships and Venture Capital Support are Indicative of the Future Potential
9.5. Once Approved, BCMA Targeted Therapies are Poised to Achieve an Accelerated Growth



  • ADC Therapeutics
  • ARCH Venture Partners
  • AbbVie
  • Abramson Cancer Center of the University of Pennsylvania
  • Acorn Campus Ventures
  • Adimab
  • Aduro Biotech
  • Advanced Technology Ventures
  • Aeris Capital
  • Affimed
  • Alaska Permanent Fund
  • Alexo Therapeutics
  • Alta Partners
  • Amgen
  • Aquilo Capital Management
  • Atlante Biotech
  • Autolus
  • BankInvest Biomedical Venture
  • Baylor College of Medicine
  • Bezos Expeditions
  • BioMedInvest
  • Bluebird bio
  • Boehringer Ingelheim
  • Bristol-Myers Squibb
  • California Institute for Biomedical Research
  • California Institute for Regenerative Medicine
  • Cancer Institute, University College London
  • Celgene
  • Cellectis
  • Commercial Street Capital
  • Cowen and Company
  • Credit Suisse Securities
  • Dana-Farber Cancer Institute
  • Deerfield Partners
  • Diamond Capital Company
  • Discover Growth Fund
  • Domain Associates
  • Easton Capital
  • Edmond de Rothschild Investment Partners
  • EngMab
  • Eureka Therapeutics
  • FirstVentury Equity
  • Five Prime Therapeutics
  • Forbion Capital Partners
  • French Muscular Dystrophy Association (AFM)
  • Genzyme Ventures
  • GlaxoSmithKline (GSK)
  • Harbinger Venture Capital
  • Health Canada
  • Healthcap Venture Capital
  • Heidelberg Pharma
  • Hercules Technology Growth Capital
  • Idinvest Partners
  • Immune Pharmaceuticals
  • Institute of Molecular and Cell Biology
  • JP Morgan Bay Area Equity Fund
  • Janssen Biotech
  • Janssen Pharmaceuticals
  • Jefferies
  • Johnson & Johnson
  • Juno Therapeutics
  • Kite Pharma
  • Kleiner Perkins Caufield & Byers
  • Life Sciences Partners
  • Majuven
  • Malin Corporation
  • Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC)
  • McMaster University
  • MedImmune
  • Memorial Sloan Kettering Cancer Center (MSKCC)
  • Merlin Nexus
  • Methodist Hospital, Houston
  • Micromet
  • Millennium Pharmaceuticals
  • National Cancer Institute (NCI)
  • Novartis
  • Novartis Institute for Biomedical Research
  • Novartis-Penn Center for Advanced Cellular Therapeutics
  • Novo Nordisk
  • Odyssee Venture
  • Onyx Pharmaceuticals
  • OrbiMed
  • Pfizer
  • Pontifax
  • Poseida Therapeutics
  • RA Capital
  • Ramius Capital Group
  • Ridgeback Capital Management
  • Riverbank Capital
  • Seattle Genetics
  • Shire
  • Singapore BioInnovations
  • Southwest Hospital of the Third Military Medical University, China
  • Stifel
  • Suma Venture
  • Sutro Biopharma
  • Takeda Pharmaceutical
  • Techno Venture Management Capital
  • Texas Children's Hospital
  • Texas Pacific Group
  • The Scripps Research Institute
  • The University of Texas MD Anderson Cancer Center
  • The Wellcome Trust
  • Third Rock Ventures
  • Transposagen Biopharmaceuticals
  • Triumvira Immunologics
  • University of Munich
  • VenBio
  • Venrock
  • Versant Ventures
  • Wuhan Bio-Raid Biotechnology
  • Yuan Capital

For more information about this report visit

Media Contact:

Research and Markets
Laura Wood, Senior Manager

For E.S.T Office Hours Call +1-917-300-0470
For U.S./CAN Toll Free Call +1-800-526-8630
For GMT Office Hours Call +353-1-416-8900

U.S. Fax: 646-607-1907
Fax (outside U.S.): +353-1-481-1716

To view the original version on PR Newswire, visit:

SOURCE Research and Markets
Copyright©2017 PR Newswire.
All rights reserved

Related medicine technology :

1. Asia-Pacific Non-Small Cell Lung Cancer Therapeutics Markets to 2023: Launch of Premium Targeted Therapies and Increasing Prevalence to Drive the Market - Research and Markets
2. Scientists at Invictus Oncology Design Targeted Therapy for Cancer Treatment
3. IPI-549 Featured at 15th International Congress on Targeted Anticancer Therapies
4. Global Targeted Drug Delivery Partnering 2010-2017: Deal trends, players, financials and forecasts
5. Surgical Lasers Market to Reach $2.37 Billion By 2021 - Increasing Incidence & Prevalence of Targeted Diseases
6. Precision Medicine Unlocks the Future of Targeted Therapy in the Global Healthcare Industry
7. Global Immunotherapy Drugs Market to Reach $201 Billion by 2021: Increasing Adoption of Targeted Therapies - Research and Markets
8. Limited improvement in EGFR testing rates observed in new survey with approximately one in five advanced lung cancer patients still at risk of missing out on targeted therapy
9. Increased Development of Highly-targeted Biologics Set to Change Composition of Asthma Therapeutics Market, Says GBI Research
10. Various Development Advancements for Targeted Treatment Therapies for Rare Diseases & Disorders Lead to Newest Orphan Drug Designations by the U.S. FDA
11. Personalized Medicine Market Worth $149+ Billion by 2020 Covering Companion Diagnostic and Targeted Therapeutics
Post Your Comments:
(Date:10/4/2017)... 4, 2017  South Korean-based healthcare product Development Company ... "cprCUBE" on Kickstarter. The device will educate the user ... with better efficiency compared to the dated and pricey ... on efficacy of the compression for a more informed ... goal to raise $5,000. ...
(Date:10/2/2017)... 2017 Diplomat Pharmacy, Inc. (NYSE: ... Consulting, LLC , and named its founder as Diplomat,s ... Tennessee , will operate under Diplomat ... service offerings for health care partners to include IT ... "In an interoperable world, technology delivers comprehensive ...
(Date:10/2/2017)... -- Halo Labs announces the European launch of their new low ... MIBio 2017 in Cambridge, U.K on October ... biopharmaceutical samples with unprecedented speed and sensitivity while using far less ... Imaging. ... analysis system ...
Breaking Medicine Technology:
(Date:10/13/2017)... ... October 13, 2017 , ... The Visiting Nurse Association (VNA) of Somerset Hills ... specialty vendors and unique items from across the nation, this holiday-themed event will raise ... offered by the VNA. The boutique will be open Saturday, November 4 (10:00 ...
(Date:10/13/2017)... ... , ... Talented host, actor Rob Lowe, is introducing a ... episode of "Success Files," which is an award-winning educational program broadcasted on PBS ... in-depth with passion and integrity. , Sciatica occurs when the sciatic nerve in ...
(Date:10/12/2017)... ... October 12, 2017 , ... First ... compliance program management, will showcase a range of technology and learning solutions at ... (NCAL) Convention and Expo to be held October 14–18, 2017 at the Mandalay ...
(Date:10/12/2017)... PALM CITY, Fla. (PRWEB) , ... October 12, 2017 , ... ... of cold therapy products, announced today the introduction of an innovative new design of ... the multipurpose pad so you get maximum comfort while controlling your pain while using ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... Hair Restoration, has recently contributed a medical article to the newly revamped ... Dr. Mohebi’s article spotlights the hair transplant procedure known as Follicular Unit ...
Breaking Medicine News(10 mins):