Navigation Links
BARACLUDE(R) (entecavir) Data Continue to Demonstrate Low Incidence of Resistance Through Five Years of Treatment in Nucleoside-naive Chronic Hepatitis B Patients
Date:3/24/2008

gap of less than or equal to 35 days.

Viral load reduction in chronic hepatitis B patients treated with BARACLUDE(R) (entecavir) in nucleoside-naive and lamivudine-refractory studies was also evaluated.

Data Results

Results from these studies prior to this year five analysis were previously announced on April 14, 2007.

Nucleoside-naive data

-- The incidence of BARACLUDE resistance in patients in

nucleoside-naive studies over time is low, with a cumulative

probability of genotypic BARACLUDE resistance of 1.2 percent

through five years.

-- No nucleoside-naive patient developed resistance (n=108) in year

five.

-- 93 percent of the nucleoside-naive patients taking BARACLUDE were

able to achieve and maintain an undetectable viral load

(HBV DNA <300 copies/mL) through year five (n=108).

Lamivudine-refractory data

-- The results in lamivudine-refractory patients in years one through

five were consistent with the finding that the pre-existence of

lamivudine-resistant substitutions resulted in an increase in the

emergence of BARACLUDE resistance, with a cumulative probability of

genotypic resistance of 51 percent through five years.

-- In year five, 43 percent of lamivudine-refractory patients had

virologic breakthrough with BARACLUDE resistance (n=33).

-- During this resistance monitoring program, 68 of the 187

lamivudine-refractory patients achieved undetectable viral load

(<300 copies/mL) and of these, one patient developed virologic

breakthrough due to BARACLUDE resistance.

Indication and Important Safety Information About BARACLUDE(R) (entecavir) 0.5 mg/1 mg Tablets

BARACLUDE(R) (entecavir) is a prescription medicine used for chronic infection with hepatitis B virus (HBV) in adults where the virus is multiplying and
'/>"/>

SOURCE Bristol-Myers Squibb
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Carpet One Floor & Home Continues Making Dramatic Strides in Funding Breast Cancer Research and Awareness
2. Nuvelo Announces Phase 2 SONOMA-3 Trial Did Not Meet Target Product Profile and Discontinues Alfimeprase Development
3. New Trial Presented at AAAAI Reports that the Growth of Children 2-5 Years Old with Year-Round Allergic Rhinitis Continued According to Normal Age-Adjusted Distribution Over a 6-Month Treatment with Nasacort AQ
4. Phase I and Phase I/II DCVax(R)-Brain Data Continues to Show Significantly Improved Survival Rates for Brain Cancer Patients
5. Bone Mineral Content Continues to Increase in Obese Adolescents During Weight Loss
6. Raven Announces Continued Enrollment of Phase 1/2a Clinical Trial of RAV12 Therapeutic Antibody for Treatment of Adenocarcinomas
7. The OrthoGlide(TM) Medial Knee Implant Continues to be Accepted as an Alternative to Total Knee Replacement
8. Abbotts XIENCE(TM) V Everolimus Eluting Coronary Stent Shows Continued Superiority to TAXUS Stent in Reducing Major Adverse Cardiac Events in SPIRIT III Clinical Trial
9. Boston Scientific PROMUS(TM) and TAXUS(R) Stents Continue Strong Performance in Safety and Efficacy Measures
10. Facet Solutions Enjoys Continued Clinical Success With the Anatomic Facet Replacement System (AFRS(TM))
11. FDA Advisory Committees Recommend Continued U.S. Marketing Authorization for Trasylol(R)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2015)...  iMD Companies, Inc. (ICBU) has repositioned itself as a holding ... a foothold in the hydroponic, hemp and medical marijuana sectors. ... in the sector, and recently partnering with the Chippewa Tribe ... medical marijuana, iMD is committing to bring its vision to ...
(Date:1/23/2015)... MONMOUTH JUNCTION, N.J. , Jan. 23, 2015 ... immunotherapy company commercializing its CytoSorb® extracorporeal cytokine adsorber ... surgery patients, announced the receipt of $385,642, net ... approved participant of the Technology Business Tax Certificate ...
(Date:1/23/2015)... Tianyin Pharmaceutical Inc. (NYSE Amex: TPI ), ... sale of patented biopharmaceutical medicine, modernized traditional Chinese medicine ... announced the business and development progress at its Jiangchuan ... the September 2014 JCM application (No. 51268) for the ...
Breaking Medicine Technology:iMD Companies Poised to Make Impact in Multi-Billion Dollar Medical Marijuana Sector With Recent Investments and Strategic Partnerships 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3TPI's JCM Updates on Import Registration for International Clients 2TPI's JCM Updates on Import Registration for International Clients 3TPI's JCM Updates on Import Registration for International Clients 4
... Modulator Administered in Dual Cord Blood Transplant for Hematologic MalignancyLA ... announced today that the first patient has been ... small molecule Stem Cell Modulator (SCM) designed to increase hematopoietic ... key pathways that guide cell fate. The study, which ...
... delivers Germ-Free cleaning, extending life, efficiency and healthiness of ... are almost neurotic about washing their hands and using ... at their computer and put their hands all over ... ground for these persistent little bugs, which are known ...
Cached Medicine Technology:Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 2Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 3Fate Therapeutics Announces First Patient Treated in Phase 1b Clinical Trial of FT1050 for Hematopoietic Stem Cell Support 4GreenBytes Wards Off Germs and Costly Computer Repairs 2GreenBytes Wards Off Germs and Costly Computer Repairs 3
(Date:1/22/2015)... Woodloch Pines, an all-inclusive family resort ... TripAdvisor as the number one best large hotel for families ... world for their annual Travelers’ Choice Awards. , TripAdvisor ... website is home to millions of unbiased and honest traveler ...
(Date:1/22/2015)... Angelweddingdress is a famous wedding dress company offering many ... it on Facebook, Twitter, and Pinterest. The fans will have ... a lottery every week. , Moreover, the company has extended ... Angelweddingdress homepage for more information. , Angelweddingdress ...
(Date:1/22/2015)... TX (PRWEB) January 22, 2015 A ... issue of experience and person-centeredness in the long-term care ... towards action across the continuum. The paper, “The Power ... Continuum,” engages perspectives and practices of the patient, resident ...
(Date:1/22/2015)... 2015 Joan Lunden, award-winning American journalist, ... the upcoming 32nd Annual Miami Breast Cancer Conference ... Resource®, LLC (PER®) , shares that “a fast-growing, virulent” ... if she had not followed up her clean mammogram ...
(Date:1/22/2015)... Four years since the release of their debut recording Love ... of Avasa & Matthew Love – the duo are pleased to ... through White Swan Records on February 24, 2015. , THE ROAD ... available to all of us to walk out of the mire ...
Breaking Medicine News(10 mins):Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6Health News:THE ROAD by Avasa & Matthew Love -- A New Album 2Health News:THE ROAD by Avasa & Matthew Love -- A New Album 3Health News:THE ROAD by Avasa & Matthew Love -- A New Album 4
... health, social skills in the process, experts say , FRIDAY, ... mean days spent at the beach or lake, afternoon bike ... is more likely to be lived in the not-so-great indoors, ... "human" contact. , The indoor child phenomenon concerns health experts ...
... A twice weekly hip strengthening regimen performed for six ... some cases eliminating -- knee pain referred to as ... study by Tracy Dierks, assistant professor in the Department ... based on the theory that stronger hips would correct ...
... ... better ROI , ... Rochester, NY and Piscataway NJ (PRWEB) June 4, 2010 -- UniteU Technologies, Inc., a ... optimizing solutions for online stores, are announcing the availability of Filtered Navigation Search Express ...
... Theurer Cancer Center at Hackensack University Medical Center announced ... the American Society of Clinical Oncology (ASCO) annual meeting ... Research highlights include a comparison of first-line treatments for ... of a new genetically engineered cancer therapy, and the ...
... Blood Institute (NHLBI) has stopped a clinical trial evaluating a ... children with sickle cell anemia and iron overload because of ... than the existing treatment. The 26-site trial, Stroke ... between the ages of 5 and 18 who had already ...
... role in the aging process appears to play a role ... according to researchers from the Center for Stem Cell Biology ... Jefferson University. In the study, published online in ... protein interaction that controls the silencing of Oct4, a key ...
Cached Medicine News:Health News:Move Childhood Back Outdoors This Summer 2Health News:Move Childhood Back Outdoors This Summer 3Health News:Hip exercises found effective at reducing, eliminating common knee pain in runners 2Health News:UniteU and Celebros Launch Dynamic Cross-Sell and New Version of Filtered Navigation Search 2Health News:UniteU and Celebros Launch Dynamic Cross-Sell and New Version of Filtered Navigation Search 3Health News:John Theurer Cancer Center experts present new cancer research at ASCO Annual Meeting 2Health News:John Theurer Cancer Center experts present new cancer research at ASCO Annual Meeting 3Health News:John Theurer Cancer Center experts present new cancer research at ASCO Annual Meeting 4Health News:Stroke prevention study in children with sickle cell anemia, iron overload stopped early 2Health News:Stroke prevention study in children with sickle cell anemia, iron overload stopped early 3Health News:Gene related to aging plays role in stem cell differentiation 2
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: