Navigation Links
BARACLUDE(R) (entecavir) Data Continue to Demonstrate Low Incidence of Resistance Through Five Years of Treatment in Nucleoside-naive Chronic Hepatitis B Patients
Date:3/24/2008

gap of less than or equal to 35 days.

Viral load reduction in chronic hepatitis B patients treated with BARACLUDE(R) (entecavir) in nucleoside-naive and lamivudine-refractory studies was also evaluated.

Data Results

Results from these studies prior to this year five analysis were previously announced on April 14, 2007.

Nucleoside-naive data

-- The incidence of BARACLUDE resistance in patients in

nucleoside-naive studies over time is low, with a cumulative

probability of genotypic BARACLUDE resistance of 1.2 percent

through five years.

-- No nucleoside-naive patient developed resistance (n=108) in year

five.

-- 93 percent of the nucleoside-naive patients taking BARACLUDE were

able to achieve and maintain an undetectable viral load

(HBV DNA <300 copies/mL) through year five (n=108).

Lamivudine-refractory data

-- The results in lamivudine-refractory patients in years one through

five were consistent with the finding that the pre-existence of

lamivudine-resistant substitutions resulted in an increase in the

emergence of BARACLUDE resistance, with a cumulative probability of

genotypic resistance of 51 percent through five years.

-- In year five, 43 percent of lamivudine-refractory patients had

virologic breakthrough with BARACLUDE resistance (n=33).

-- During this resistance monitoring program, 68 of the 187

lamivudine-refractory patients achieved undetectable viral load

(<300 copies/mL) and of these, one patient developed virologic

breakthrough due to BARACLUDE resistance.

Indication and Important Safety Information About BARACLUDE(R) (entecavir) 0.5 mg/1 mg Tablets

BARACLUDE(R) (entecavir) is a prescription medicine used for chronic infection with hepatitis B virus (HBV) in adults where the virus is multiplying and
'/>"/>

SOURCE Bristol-Myers Squibb
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Carpet One Floor & Home Continues Making Dramatic Strides in Funding Breast Cancer Research and Awareness
2. Nuvelo Announces Phase 2 SONOMA-3 Trial Did Not Meet Target Product Profile and Discontinues Alfimeprase Development
3. New Trial Presented at AAAAI Reports that the Growth of Children 2-5 Years Old with Year-Round Allergic Rhinitis Continued According to Normal Age-Adjusted Distribution Over a 6-Month Treatment with Nasacort AQ
4. Phase I and Phase I/II DCVax(R)-Brain Data Continues to Show Significantly Improved Survival Rates for Brain Cancer Patients
5. Bone Mineral Content Continues to Increase in Obese Adolescents During Weight Loss
6. Raven Announces Continued Enrollment of Phase 1/2a Clinical Trial of RAV12 Therapeutic Antibody for Treatment of Adenocarcinomas
7. The OrthoGlide(TM) Medial Knee Implant Continues to be Accepted as an Alternative to Total Knee Replacement
8. Abbotts XIENCE(TM) V Everolimus Eluting Coronary Stent Shows Continued Superiority to TAXUS Stent in Reducing Major Adverse Cardiac Events in SPIRIT III Clinical Trial
9. Boston Scientific PROMUS(TM) and TAXUS(R) Stents Continue Strong Performance in Safety and Efficacy Measures
10. Facet Solutions Enjoys Continued Clinical Success With the Anatomic Facet Replacement System (AFRS(TM))
11. FDA Advisory Committees Recommend Continued U.S. Marketing Authorization for Trasylol(R)
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/21/2015)...  Cardica, Inc. (Nasdaq: CRDC ) today announced that ... the company,s vice president of operations, was granted an option ... a per share exercise price of $0.43, the closing trading ... pursuant to Cardica, Inc.,s Inducement Plan, which was approved by ... 5653(c)(4) of the Nasdaq Global Market for equity grants to ...
(Date:5/21/2015)... , 21. Mai 2015 /PRNewswire/ ... DPRX ), ein Unternehmen für Arzneimittel ... die Entwicklung und Vermarktung von Locilex® ... kündigte heute eine wissenschaftliche Posterpräsentation an, ... des Unternehmens vorstellt, OneStep-1 und OneStep-2, ...
(Date:5/21/2015)... WASHINGTON , May 21, 2015 ... Century Cures legislation by the House Energy ... (SCPC) thanked the Committee for recognizing the unique ... providers, and for including bill language exempting Part ... settings from a proposed medication management "lock-in" provision. ...
Breaking Medicine Technology:Cardica Announces New Employment Inducement Grant 2Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 2Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 3Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 4Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 5Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 6Dipexium kündigt eine Präsentation auf dem 7. International Symposium on the Diabetic Foot an 7SCPC Applauds Unanimous House Panel Passage of 21st Century Cures Bill Recognizing Unique Challenges Facing Long Term Care (LTC) Pharmacy Patients, Providers 2
... (Hologic or the Company) (Nasdaq: HOLX ), ... medical imaging systems and surgical products dedicated to serving ... release its fourth quarter fiscal 2010 operating results on ... with the release, management will host a conference call ...
... Reportlinker.com announces that a new market ... US Pharmaceutical Market Overview ... patent cliff set to impact Pharma ... IntroductionThe US prescription pharmaceutical market was ...
Cached Medicine Technology:Hologic to Release Fourth Quarter Fiscal 2010 Operating Results on Monday, November 8, 2010 2Reportlinker Adds US Pharmaceutical Market Overview - Healthcare reform, economic pressures and the patent cliff set to impact Pharma 2Reportlinker Adds US Pharmaceutical Market Overview - Healthcare reform, economic pressures and the patent cliff set to impact Pharma 3
(Date:5/24/2015)... 2015 The federal court overseeing ... has scheduled its next monthly Case Management Conference ... According to court documents filed in the U.S. ... will be convened on June 2, 2015, at ... Liability Litigation - MDL No. 2545) , “Our ...
(Date:5/24/2015)... Indiana Fiber Network, LLC (IFN), the leading Indiana ... Inc. (MTA) has selected IFN as a fiber transport ... Sales Manager, fiber route diversity and network redundancy are ... MTA with the diverse fiber transport from their Merrillville ... voice carriers located at Henry Street in Indianapolis, IN. ...
(Date:5/24/2015)... 24, 2015 ... - The students were selected ... the fourth annual A Day of ... Geneva National in Lake Geneva. , ... High School,         Jonathan Alfonso,         Bridget Keefe, ...
(Date:5/23/2015)... 23, 2015 On Saturday, May 23, 2015, ... playground for Branches Florida City exactly five years to the ... in 2010. , A large fire tore through the Branches ... 23, 2010 in the middle of the night as neighbors, ... later declared arson even though it is suspected that the ...
(Date:5/23/2015)... Dr. David Benvenuti, an experienced plastic surgeon who practices ... article to his website that takes an in-depth look ... in the fascinating blog, he has recently had several young ... as “gauging,” the technique involves placing larger and larger gauge ... eventually stretch the holes out to incredible sizes. As the ...
Breaking Medicine News(10 mins):Health News:Testosterone Lawsuit Attorneys at Bernstein Liebhard LLP Look Ahead to June Conference in Federal Multidistrict Litigation 2Health News:Testosterone Lawsuit Attorneys at Bernstein Liebhard LLP Look Ahead to June Conference in Federal Multidistrict Litigation 3Health News:Indiana Fiber Network, LLC Enables Midwest Telecom of America with Fiber Route Diversity 2Health News:Mercy Foundation Honors 16 Students for Making a Difference - Mercy Health System Javon Bea 2Health News:Five Years After Fire, Branches Rebuilds Playground 2Health News:Dr. Benvenuti, a Plastic Surgeon in Newport Beach, CA, Posts New Article about Repairing Ear Gauges 2
... students for careers in high-demand fieldsMINNEAPOLIS, Feb. 16 ... of online degrees, is offering three new degree programs ... the fields of nursing, instructional design and technology, and ... Science in Nursing, B.S. in Instructional Design and Technology, ...
... 16 my 1HIE, LLC (My ... million e-Prescriptions have been sent from over 700 affiliated ... with physicians to help them actively adopt the usage ... Portal. Working with its member physicians organizations, my ...
... Familiar products. Same flavors. Fewer caloriesFORT WORTH, ... lead the Hispanic baking industry by becoming ... complete line of 100 Calorie products. Building ... moderation, the 100 Calorie line offers the ...
... Inc. (NYSE:MDT) and Envisionier Medical Technologies, Inc., a privately held company, ... and marketing of the endogo® system to the ENT (ear, nose, ... ... (PRWEB) February 16, 2009 -- Envisionier is the developer of the ...
... - Two current members step down to become ... a leading provider of wireless, handheld barcode ... that Ms. Margaret Laub, Chief Executive Officer of ... joined the IntelliDOT Board of Directors. (Logo: ...
... their electroplating, anodizing, and electropolishing plant. , ... Toccoa, ... completion of their new 16, long, 27 station aluminum anodizing line. ... works for some time now and even though the economy is ...
Cached Medicine News:Health News:Walden University Offers a New M.S. in Leadership Degree and New Bachelor's Degrees in Instructional Design and Technology and in Nursing 2Health News:Walden University Offers a New M.S. in Leadership Degree and New Bachelor's Degrees in Instructional Design and Technology and in Nursing 3Health News:my1HIE Reaches 1 Million e-Prescriptions 2Health News:Marinela USA(R) Launches 100 Calorie Product Line 2Health News:Envisionier and Medtronic Announce Agreement 2Health News:Margaret Laub Appointed to IntelliDOT Board of Directors 2Health News:Margaret Laub Appointed to IntelliDOT Board of Directors 3Health News:Margaret Laub Appointed to IntelliDOT Board of Directors 4
Greenberg micro instrument holder is a flexbar arm used to hold micro instruments used repeatedly within retracted fields. Holds instruments with shafts up to 1/8 in diameter....
Greenberg universal retractor case, with four compartments to hold various components....
Length-9 (229 mm) Tapered retractor blades....
Kit is supplied with four secondary bars. Secondary bars attach to primary bar. Length 12 (305 mm)....
Medicine Products: