Navigation Links
Avastin Achieves Impressive Rate of Curative Surgery in Patients with Advanced Colorectal Cancer
Date:9/23/2007

oval of the metastatic lesions (R0 resection) was achieved in 170 patients, an impressive success rate of 79%. The best outcomes as expected were achieved in the subgroup of patients with metastatic disease confined to the liver only (n=704). In this subgroup, 102 (14.5%) patients underwent surgical removal of their liver metastases in curative intent with successful complete (R0) resection achieved in 81 patients.

No increase in wound-healing complications or bleeding incidents was observed compared with historical controls underlining the favourable safety profile of Avastin in this setting.

Colorectal cancer is the third most common cancer with approximately one million new cases worldwide every year. It is estimated that over 50% of people diagnosed with colorectal cancer will die of the disease(1).

About First BEAT

First BEAT is an international phase IV trial which has enrolled 1965, community based patients from 41 countries worldwide. Patients diagnosed with unresectable metastatic disease received Avastin in combination with standard first line chemotherapy; the most common regimens were FOLFOX, XELOX, FOLFIRI and Xeloda (capecitabine). The dose of Avastin used was equivalent to 2.5 mg/kg/week (5 mg/kg every 2 weeks with 5-FU-based regimens and 7.5 mg/kg every 3 weeks with capecitabine-based regimens).

First BEAT completed recruitment in February 2006. The primary endpoint was safety. General efficacy and surgery with curative intent were preplanned secondary endpoints and data were collected in a prospective fashion. Efficacy data from the BEAT trial are continuing to be evaluated with further data presentations expected at upcoming oncology conferences.

Additional information

- Roche in Oncology: http://www.roche.com/pages/downloads/company/pdf/mboncology05e_b.pdf

- Roche Health Kiosk, Cancer:

SOURCE Roche
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Biotheras Imprime PGG Enhanced Effectiveness of Avastin in Cancer Study
2. FDA MedWatch: Avastin (bevacizumab) and Formation of Tracheoesophageal Fistula in a Recent Clinical Study in Patients with Limited-stage Small Cell Lung Cancer
3. Data Presented at AACR Meeting Shows Peregrines Selective Anti-VEGF Antibodies are as Effective as Avastin(R) in Preclinical Cancer Models
4. Cethromycin Achieves Primary Endpoint in Pivotal Phase 3 Pneumonia Clinical Trial
5. Hypertension Vaccine CYT006-AngQb Achieves Strong Blood Pressure Reduction During Important Early Morning Period When Most Adverse Cardiovascular Events Occur
6. Ontak (denileukin diftitox) Achieves 49.1% Overall Response Rate in Phase III Trial of Cutaneous T-Cell Lymphoma (CTCL)
7. Micromet Achieves Milestone in BiTE Research Collaboration with MedImmune
8. Addex Achieves Statistically Significant Outcome in Phase IIa Clinical Trial With ADX10059 in Gastro-Esophageal Reflux Disease
9. Vicals Vaxfectin Adjuvant Achieves Dose-Sparing Effect With Seasonal Influenza Vaccine
10. Mymetics HIV Vaccine Achieves Research Breakthrough, Eliciting Protective Antibody Response in Mucosal Tissues of Non-Human Primate Model
11. Integrated Biopharmas Proprietary Vaccine Technology Achieves Strong Positive Results
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... EASTON, Mass. , July 22, 2014 ... or the "Company") and Parabase Genomics ("Parabase"), ... entered into a strategic research and development ... the collaboration, PBI will develop a front-end, ... molecular diagnostics and newborn confirmatory testing process. ...
(Date:7/22/2014)... WASHINGTON, New York , July ... Neue Partnerschaft für umfassenden Schutz ... Medikamenteneinwirkungen in Österreich    ... Anbieter von geschlossenen Transfersystemen (Closed System Transfer Devices, CSTDs) ... Medikus , einen Vertriebshändler und Hersteller ...
(Date:7/21/2014)... , July 21, 2014  Champions Oncology (OTC: CSBR), ... solutions and services to personalize the development and use ... financial and operational results for the fourth quarter and ... 24, 2014, after market close. The company ... that day at 4:30 p.m. EDT (1:30 p.m. PDT). ...
Breaking Medicine Technology:Pressure BioSciences to Develop Front-end Sample Preparation for Parabase Genomics' Targeted Next Generation Sequencing Testing Platform 2Pressure BioSciences to Develop Front-end Sample Preparation for Parabase Genomics' Targeted Next Generation Sequencing Testing Platform 3Pressure BioSciences to Develop Front-end Sample Preparation for Parabase Genomics' Targeted Next Generation Sequencing Testing Platform 4Equashield ernennt Medikus zu seinem exklusiven österreichischen Vertriebspartner für seine geschlossenen Arzneimitteltransfersysteme 2
... 2011 MedShape Solutions, the industry leader in innovative ... been named as a graduate of Georgia Tech,s Advanced ... at the 2011 ATDC Startup Showcase to be held ... Conference Center, where emerging technology company members and graduate ...
... NEW YORK, March 28, 2011 Havas Drive, the ... launch of patient-centric services geared toward persons with disabilities ... Kel Smith—a nationally recognized authority on Web accessibility with ... the Pentagon Library, Kent State,s Knowledge Management program and ...
Cached Medicine Technology:MedShape Solutions, Inc. Named ATDC Graduate 2MedShape Solutions, Inc. Named ATDC Graduate 3Havas Drive Launches New Services Aimed at Improving Digital and Web Accessibility 2
(Date:7/22/2014)... 2014 The Latin America Drilling fluid and ... and completion fluid market in Latin America with analysis and ... in Latin America is estimated to grow from around $0.93 ... CAGR of 9.2%, for the given period. , Browse through ... fluid Market Report, to get an idea of the in-depth ...
(Date:7/22/2014)... 22, 2014 The Middle East Drilling fluid ... fluid and completion fluid market in Middle East with analysis ... market in Middle East is estimated to grow from around ... a CAGR of 5.7%, for the given period. , Browse ... completion fluid Market report, to get an idea of the ...
(Date:7/22/2014)... Dimension One Spas’ retailers across the ... all models during the “Let’s Take This Outside” Summer ... http://www.d1spas.com/financing for more information and to apply. ... offers a wide variety of outdoor hot tubs with ... music, customizable massage, and personal controls. , ...
(Date:7/22/2014)... Marine threats from human or natural agents such ... international criminal and piracy threats have created more ... Due to this the worldwide revenue of the ... and is expected to reach $20.87 billion in ... to grow at a CAGR of 8.40%. , ...
(Date:7/22/2014)... 22, 2014 Location-based services (LBS) ... on location-based data. The retail and food and ... to reduce transportation costs. Due to these factors, ... reached $8.12 billion in 2014, and is expected ... calculated CAGR of 37.50% during this period. Top ...
Breaking Medicine News(10 mins):Health News:Latin America Drilling Fluid & Completion Fluid Market is Expected to Reach $1.45 Billion in 2018 - New Report by MicroMarket Monitor 2Health News:Latin America Drilling Fluid & Completion Fluid Market is Expected to Reach $1.45 Billion in 2018 - New Report by MicroMarket Monitor 3Health News:Latin America Drilling Fluid & Completion Fluid Market is Expected to Reach $1.45 Billion in 2018 - New Report by MicroMarket Monitor 4Health News:Latin America Drilling Fluid & Completion Fluid Market is Expected to Reach $1.45 Billion in 2018 - New Report by MicroMarket Monitor 5Health News:Latin America Drilling Fluid & Completion Fluid Market is Expected to Reach $1.45 Billion in 2018 - New Report by MicroMarket Monitor 6Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 2Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 3Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 4Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 5Health News:Middle East Drilling Fluid & Completion Fluid Market is Expected to Reach $740 Million in 2018 - New Report by MicroMarket Monitor 6Health News:North America Maritime Security Market is Expected to Reach $4.76 billion in 2019 - New Report by MicroMarket Monitor 2Health News:North America Maritime Security Market is Expected to Reach $4.76 billion in 2019 - New Report by MicroMarket Monitor 3Health News:North America Maritime Security Market is Expected to Reach $4.76 billion in 2019 - New Report by MicroMarket Monitor 4Health News:North America Location Based Services (LBS) Market is Expected to Reach $13.10 Billion in 2019 - New Report by MicroMarket Monitor 2Health News:North America Location Based Services (LBS) Market is Expected to Reach $13.10 Billion in 2019 - New Report by MicroMarket Monitor 3Health News:North America Location Based Services (LBS) Market is Expected to Reach $13.10 Billion in 2019 - New Report by MicroMarket Monitor 4Health News:North America Location Based Services (LBS) Market is Expected to Reach $13.10 Billion in 2019 - New Report by MicroMarket Monitor 5
... Inc. (Nasdaq: HOLX ), a leading developer, manufacturer ... products dedicated to serving the healthcare needs of women, today ... results on Monday, February 2, 2009 after market close. In ... on Monday, February 2, 2009 at 5:00 p.m. (eastern). , ...
... mental rotation, which is the ability to identify how ... Now, a University of Iowa study shows a connection ... parietal lobe, the brain region that controls this type ... to differ between men and women, with women,s parietal ...
... the nonprofit,organ and tissue recovery organization for Northeast Ohio, ... announcing the first,near total face transplant in the United ... following statement is from LifeBanc Chief Executive Officer Gordon,Bowen. ... with LifeBanc,s mission of helping to improve and save ...
... Fifteen-year old Musa was only two when he became an orphan after ... , After their death, Musa first went to live ... too young to fully understand who his parents were then, he is ... , Every year, more than 600,000 children are orphaned by ...
... Hospitals to Meet Joint Commission Compliance through Patient Engagement , ... In an effort to improve patient safety and ... Interactive Patient Care (IPC) solutions, is enabling King,s Daughters Medical ... National Patient Safety Goal (NPSG) 16 through GetWellNetwork,s interactive ...
... et al. released this week and scheduled to be published ... Internal Medicine , concluded that while screening colonoscopy is associated ... limited to deaths from cancer developing in the left side ... as a screening test and clarifies a possible weakness: ...
Cached Medicine News:Health News:Hologic, Inc. to Release First Quarter Fiscal 2009 Operating Results on Monday, February 2, 2009 2Health News:Sex difference on spatial skill test linked to brain structure 2Health News:LifeBanc Assists Cleveland Clinic in First Near Total Face Transplant in the United States 2Health News:CCF Connects Parents With Their Children Through the Power of a Memory 2Health News:King's Daughters Medical Center Leverages Unique Bedside Interactive Technology to Meet Requirements of Patient Safety Goal 16 2Health News:King's Daughters Medical Center Leverages Unique Bedside Interactive Technology to Meet Requirements of Patient Safety Goal 16 3Health News:Annals colonoscopy study underscores importance of quality standards 2
Jography angiographic catheter has a new material combination, a patented angled weld, a flat wire braid design with a XXL lumen. It also has an atraumatic soft tip....
Femoral selective diagnostic catheter.The material used is polyurethane (DUCOR). All selective shapes have thrulumen design. Guidewire campatibility is 0.038". Packaging 5/Box....
... The INFINITI 4F, ... of diagnostic catheters is ... These products incorporate state-of-the-art ... nylon to deliver better ...
The advanced center-of-the-arc system allows an infinite choice of trajectories. The system's lightweight durable frame provides accuracy, simplicity, patient mobility and accessibility....
Medicine Products: