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Avanafil Data Presented at the European Society of Sexual Medicine Meeting
Date:12/5/2011

MOUNTAIN VIEW, Calif., Dec. 5, 2011 /PRNewswire/ -- VIVUS, Inc. (NASDAQ: VVUS) today announced that multiple abstracts were presented over the weekend at the 2011 European Society of Sexual Medicine (ESSM) Meeting in Milan, Italy.  The ESSM is the largest gathering of medical professionals specializing in sexual dysfunction and treatment in Europe.

The specific abstracts that were presented on December 3rd, 2011 include:

A moderated poster presentation by Laurence H. Belkoff, DO, FACOS, Chairman of the Department of Specialty Surgeries and the Division of Urology at the Philadelphia College of Osteopathic Medicine, entitled:

An Open-label, Long-term Evaluation of the Safety and Tolerability of Avanafil in Males with Erectile Dysfunction

Dr. Belkoff reported that in the study (TA-314) avanafil met all endpoints by demonstrating sustained improvement from baseline in erectile function as measured by the Sexual Encounter Profile (both SEP 2 and SEP 3) and improvements in the International Index of Erectile Function (IIEF).  The study also suggested a favorable side effect profile and successful intercourse (as measured by SEP 3) in as little as 15 minutes in some patients, without any restrictions on food or alcohol intake.  More than 88% of subjects study-wide responded to treatment with avanafil 100mg or 200mg.

A moderated poster presentation by Run Wang, MD, Associate Professor of Surgery in the Division of Urology and holder of the Cecil M. Crigler, MD Chair in Urology at the University of Texas Health Science Center in Houston, entitled:

Avanafil, a Highly Selective Phosphodiesterase Type 5 Inhibitor for the Treatment of Erectile Dysfunction: Selectivity for Eleven PDE Isozymes, in Comparison With Sildenafil, Tadalafil and Vardenafil

Dr. Wang shared his analysis of avanafil selectivity for the ele
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SOURCE VIVUS, Inc.
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